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Background: There has been a notable decrease in antibiotic prescribing in the last thirty years in Sweden. Little is known about factors influencing antibiotic prescribing over several years. Objective: To compare primary care physicians who, over time, reduced their antibiotic prescribing for respiratory tract infections with those who remained either high or low prescribers regarding potentiall
The present study collected a wide range of experimental data samples, including 855 records from various types of cylindrical weirs under diverse hydraulic conditions, setting the stage for an in-depth analysis for modeling of discharge coefficient. For this purpose, the prediction capability of four kernel-based methods (SVM, GPR, KELM, and KRR) and four neural network-based methods (FFBP, CFBP,
In November 2022 the European Commission launched a new regulatory framework proposal for packaging and packaging waste, EU Packaging and Packaging Waste Regulation, which includes mandatory reuse and refill targets of packed food products. With specific focus on perishable liquid food products, such as dairy, plant-based beverages, juices, and nectars, which are currently primarily available in s
Titan aluminium alloys belong to the group of α–β-alloys, which are used for many applications in industry due to their advantageous mechanical properties, e.g. for laser powder bed fusion (PBF-LB) processes. However, the composition of the crystal structure and the respective magnitude of the solid fraction highly influences the material properties of titan aluminium alloys. Specifically, the the
The Horizon 2020 project EU 1.5°C Lifestyles aims to mainstream lifestyles aligned with the aspirational target of the Paris Agreement. The project analyzes lifestyle perspectives at the household level and links them to studies of relevant political and socio-economic structures at various levels of government. Within this project, Citizen Thinking Labs were organized in five EU countries to expl
Preventing and mitigating damage to the surroundings arising from process safety incidents is an important aspect of process safety. Risk-informed or risk-based decision-making are cornerstones in most countries’ regulatory regimes for land-use planning. However, the design and implementation of the regulations vary significantly - from countries that have chosen a highly standardized set of rules
Remote sensing (RS) data provide large-scale observations to measure water quality parameters (WQPs) like turbidity (Turb), which indicates the haziness of the water. Accurately estimating these parameters solely from RS data is inherently complex due to various factors, necessitating the use of advanced models capable of capturing the intricate relationships between RS spectral bands as an input
A search for high-mass resonances decaying into a Formula Presented-lepton and a neutrino using proton-proton collisions at a center-of-mass energy of Formula Presented is presented. The full run 2 data sample corresponding to an integrated luminosity of Formula Presented recorded by the ATLAS experiment in the years 2015-2018 is analyzed. The Formula Presented-lepton is reconstructed in its hadro
Background: Childhood cancers affect about 350 children every year in Sweden and are life-threatening diseases. During the treatment period, situations arise that can become morally challenging for the child. When knowing children’s values and morally challenging situations in childhood cancer care, targeted ethics support could be developed and used in care. Aim: To explore children’s values and
Background: Parkinson's disease (PD) is characterized by alpha-synuclein (α-Syn) pathology, neurodegeneration and neuroinflammation. Human leukocyte antigen (HLA) variants associated with PD and α-Syn specific CD4+ T lymphocytes in PD patients highlight the importance of antigen presentation in PD etiology. The class II transactivator (CIITA) regulates major histocompatibility complex class II (MH
A combination of searches for a new resonance decaying into a Higgs boson pair is presented, using up to 139 fb^{-1} of pp collision data at sqrt[s]=13 TeV recorded with the ATLAS detector at the LHC. The combination includes searches performed in three decay channels: bb[over ¯]bb[over ¯], bb[over ¯]τ^{+}τ^{-}, and bb[over ¯]γγ. No excess above the expected Standard Model background is observed
Background: With the approval of disease-modifying treatments (DMTs) for early Alzheimer’s disease (AD), there is an increased need for efficient and non-invasive detection methods for cerebral amyloid-β (Aβ) pathology. Current methods, including positron emission tomography (PET) and cerebrospinal fluid (CSF) analysis, are costly and invasive methods that may limit access to new treatments. Plasm
Accurate monitoring of daily precipitation is essential for many applications, such as simulation and prediction of watershed water-related disasters. However, precipitation data from satellite and gauge-based precipitation products face challenges in capturing true observations because of their large uncertainties. To improve daily precipitation estimates, this study proposed a new merging framew
Agriculture faces a major challenge in meeting the world’s growing demand for food in a sustainable manner in the face of increasing environmental pressures, in particular the growing impact of climate change. Agriculture is also a major contributor to climate change. Digital technologies in agriculture can contribute to climate change adaptation and mitigation. This paper examines the interaction
Syndromic testing for lower respiratory tract infections with BioFire® FilmArray® Pneumonia Panel Plus (BF) detects 27 pathogens with a turn-around-time of one hour. We compared the performance of BF with culture. Samples from 298 hospitalized patients with suspected pneumonia routinely sent for culture were also analyzed using BF. Retrospectively, patients were clinically categorized as having "p
Iran has yet to be the subject of research looking into the gaps in the nationality law, which, could create and perpetuate statelessness. There were however, several pre-identified populations, some members of which are believed to be affected by statelessness, as well as gender discrimination in the nationality law - which causes and increases the risk of rendering children stateless. Therefore,
BackgroundThere is a need to enhance access to and support for self-management of activities in everyday life after a stroke. Internet-based solutions have the potential to contribute to this development. Consequently, an internet-based intervention called Strategies for Empowering Activities in Everyday Life (SEE) was developed. The intervention aims to assist clients in developing management str
Time-series of high throughput gene sequencing data intended for gene regulatory network (GRN) inference are often short due to the high costs of sampling cell systems. Moreover, experimentalists lack a set of quantitative guidelines that prescribe the minimal number of samples required to infer a reliable GRN model. We study the temporal resolution of data vs. quality of GRN inference in order to
Purpose: We present a comprehensive investigation into the organizational, social, and ethical impact of implementing digital breast tomosynthesis (DBT) as a primary test for breast cancer screening in Italy. The analyses aimed to assess the feasibility of DBT specifically for all women aged 45–74, women aged 45–49 only, or those with dense breasts only. Methods: Questions were framed according to
