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The determination of drug-protein binding and free drug concentration in plasma applying the equilibrium sampling through membrane (ESTM) technique has been studied using supported liquid membrane extraction in a single hollow fibre without any membrane carrier. In the extraction setup, the donor phase (plasma or buffer) was placed in the vial, into which was immersed the hollow fibre with the acc
Sixty-nine consecutive patients ( median age 54 years) were prospectively enrolled in a single-institution protocol for allogeneic transplantation with adjusted non-myeloablative fludarabine - melfalan-based conditioning including cyclosporin A and MMF, and one of three modes of serotherapy. Thirty-one donors (45%) were unrelated. The first cohort of 29 had ATG (Thymoglobulin 2 mg/kg x 3 days), th
The genetic variation of Duddingtonia flagrans, which has become a promising biocontrol agent of animal parasitic nematodes, was investigated in a worldwide collection of 22 isolates. We analysed the sequence variation in four nuclear genes, tubA (beta-tubulin), CMD1 (calmodulin), EF1alpha (translation elongation factor 1alpha), and PII (extracellular serine protease). 1428 aligned base pairs (bp)
Background: Female urinary incontinence is a prevalent condition, but only about one-third of women seek treatment. Objectives: To describe the health care provision for women with urinary incontinence from a European perspective, selecting France, Germany, Spain, Sweden, and the United Kingdom as examples, and to investigate whether specific barriers for treatment exist. Methods: Available health
Experiments were performed in the temperature range of 294 - 1143 K in pure CO2 using high-resolution rotational coherent anti-Stokes Raman spectroscopy (CARS), in the dual-broadband approach. Experimental single-shot spectra were recorded with high spectral resolution using a single-mode Nd:YAG laser and a relay imaging lens system on the exit of a 1 m spectrometer. A theoretical rotational CARS
Oxidative addition of the silanes R3SiH (R3= Ph3, Et3, EtMe2) to the unsaturated cluster [Os3(µ-H){µ3-Ph2PCH2PPh(C6H4)}(CO)8] leads to the saturated clusters [Os3(µ-H)(SiR3)(CO)9(µ-dppm)](SiR3= SiPh31, SiEt32 and SiEtMe23) and the unsaturated clusters [Os3(µ-H)2(SiR3){µ3-Ph2PCH2PPh(C6H4)}(CO)7](SiR3= SiPh34, SiEt35 and SiEtMe26). Structures are based on spectroscopic evidence and a XRD structure o
The clinical applicability of the revised McDonald diagnostic criteria of primary progressive multiple sclerosis (PPMS) was assessed in 17 patients with a longstanding PPMS diagnosis (mean 15 years). All patients were re-evaluated with clinical examinations, magnetic resonance imaging (MRI) of the brain and the spinal cord, extensive laboratory tests, and 12 patients underwent cerebrospinal fluid
Threshold stress, σth, for reorientation of hydrides in cold worked and stress-relieved (CWSR) Zr–2.5Nb pressure tube material was determined in the temperature range of 523–673 K. Using tapered gage tensile specimen, mean value of σth was experimentally determined by two methods, half thickness method and area compensation method. The difference between local values of σth measured across the thi
The main purpose with this study is to examine if there has been any changes in the governtment directive to the swedish social insurance agency(Försäkringskassan) about care assistans and examine how the swedish social insurence agency and the volunteer organisations respond to the directives. Another aim with the study is to compare the goverment and the swedish social insurence agencys opinions
Abstrakt. Bakgrund: Genom Platt reformen och barnkonventionen samt NOBABs föreskrifter har nu barnet rätt till att ha sin förälder hos sig på sjukhuset dygnet runt, från att det tidigare inte var tillåtet för en förälder att vara hos sitt barn. Genom att involvera hela familjen utifrån ett familjecentrerat perspektiv stärks barnets trygghet och välbefinnande. Barn i olika åldrar har olika behov a
Adaptation of modern Unmanned Aerial Vehicle (UAV) and multispectral sensor technology in agriculture can enhance the capacity to accurately monitor crops. But these technologies come with its own set of challenges. The major challenge is the understanding of radiometric distortions, which is particularly important while comparing data over different lighting conditions. The study developed and as
Utländska studier på militära veteraner visar på att psykiska sjukdomar, såsom Posttraumatiskt stressyndrom (PTSD) till följd av missionen förekommer. Samtidigt som studier på svenska militära utlandsveteraner uppvisat en lägre frekvens av PTSD. Den här studien undersökte kvantitativt hur det psykologiska stödet ser ut och hur det påverkar förekomsten av PTSD hos de svenska militära veteranerna. SInternational studies of military veterans display that psychological illnesses, like Posttraumatic Stress Syndrome (PTSD), exists as a result of the missions. Studies of Swedish military veterans indicates a lower frequency of PTSD, than foreign military veterans. This study used a quantitative method to investigate how the psychological supportive functions by the Swedish armed forces affect the
Inadequate water infrastructural development and high costs of water are few of the many challenges that affect water access in Kibera. Consequently, many alternatives to piped water grew out of necessity to meet the needs of residents. The aim of this thesis is to examine the conditions that have led to poor water provision in Kibera and how transitions to improved water access can be achieved by
Based on data from the past, predictive analytics can give a competitive advantage for companies when it is used to forecast the future. Specifically, predictive analytics can be used to aid decision makers in strategic planning. As the construction industry faces challenges with both more costly and complicated projects, predictive analytics can support decision makers in the industry in the most
The United States has the highest incarceration rate in the world. The phenomenon of mass incarceration largely confines minorities and people living in poverty. More than 600,000 prisoners are released yearly to face barriers of reentering society. Struggles of finding employment, housing, and being denied social services, due to their criminal record, generate a system where former inmates becom
Internetanvändare exponeras dagligen för reklam och i sociala medier flödar reklam anpassad för att tilltala varje enskild individ. Internetreklam är svårare att identifiera, undvika och förhålla sig kritisk till jämfört med reklam i traditionella medier då internetreklam ofta är inbäddad i icke-kommersiellt innehåll. På internet är det tillåtet att rikta reklam till barn i alla åldrar, för tv ochEvery day, internet users are exposed to advertising, and social media advertising feeds are tailored to appeal to the interests of the individual user. Advertising on the internet is more difficult to identify, avoid, and critique compared to advertising in traditional media, this is because much of the advertising on the internet is embedded in non-commercial content such videos on internet plat
Hälso- och sjukvårdspersonal har varit en av de yrkesgrupper som först fick vaccinera sig mot covid-19. Smittspridningen inom yrkesgruppen har dock fortsatt varit stor. För att minska smittspridning och trygga patientsäkerheten har regioner i Sverige infört vaccinationskrav för hälso- och sjukvårdspersonal. Med stöd av den rättsdogmatiska metoden utreder uppsatsen följderna beslutet att inte vacciHealthcare professionals have been one of the first occupational groups that got vaccinated against covid-19. Nevertheless, the spread of infection within the occupational group have continued to be high. To reduce the spread of infection and to safeguard patient safety regions in Sweden have introduced vaccine mandates towards its healthcare professionals. With support from the legal dogmatic met
Det straffrättsliga regelverket för lagöverträdare i åldersgruppen 18-20 år, så kallade unga myndiga lagöverträdare, genomgick vid årsskiftet stora förändringar. Under flera sekel var unga myndiga lagöverträdare i Sverige föremål för straffrättslig särbehandling i form av en ungdomsreduktion. Den tidigare regleringen innebar att för brott någon begått innan han eller hon fyllt 21 år skulle dennes Criminal law regarding offenders in the age group 18 to 20 years old, so called juvenile offenders, was changed extensively at the turn of the year. For a long time, Swedish juvenile offenders were subject to differential treatment due to their age, in the form of a reduced sentencing. Previous legislation meant that crimes committed before the age of 21 was to take the offender's young age in
