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The determination of drug-protein binding and free drug concentration in plasma applying the equilibrium sampling through membrane (ESTM) technique has been studied using supported liquid membrane extraction in a single hollow fibre without any membrane carrier. In the extraction setup, the donor phase (plasma or buffer) was placed in the vial, into which was immersed the hollow fibre with the acc
Sixty-nine consecutive patients ( median age 54 years) were prospectively enrolled in a single-institution protocol for allogeneic transplantation with adjusted non-myeloablative fludarabine - melfalan-based conditioning including cyclosporin A and MMF, and one of three modes of serotherapy. Thirty-one donors (45%) were unrelated. The first cohort of 29 had ATG (Thymoglobulin 2 mg/kg x 3 days), th
The genetic variation of Duddingtonia flagrans, which has become a promising biocontrol agent of animal parasitic nematodes, was investigated in a worldwide collection of 22 isolates. We analysed the sequence variation in four nuclear genes, tubA (beta-tubulin), CMD1 (calmodulin), EF1alpha (translation elongation factor 1alpha), and PII (extracellular serine protease). 1428 aligned base pairs (bp)
Background: Female urinary incontinence is a prevalent condition, but only about one-third of women seek treatment. Objectives: To describe the health care provision for women with urinary incontinence from a European perspective, selecting France, Germany, Spain, Sweden, and the United Kingdom as examples, and to investigate whether specific barriers for treatment exist. Methods: Available health
Experiments were performed in the temperature range of 294 - 1143 K in pure CO2 using high-resolution rotational coherent anti-Stokes Raman spectroscopy (CARS), in the dual-broadband approach. Experimental single-shot spectra were recorded with high spectral resolution using a single-mode Nd:YAG laser and a relay imaging lens system on the exit of a 1 m spectrometer. A theoretical rotational CARS
Oxidative addition of the silanes R3SiH (R3= Ph3, Et3, EtMe2) to the unsaturated cluster [Os3(µ-H){µ3-Ph2PCH2PPh(C6H4)}(CO)8] leads to the saturated clusters [Os3(µ-H)(SiR3)(CO)9(µ-dppm)](SiR3= SiPh31, SiEt32 and SiEtMe23) and the unsaturated clusters [Os3(µ-H)2(SiR3){µ3-Ph2PCH2PPh(C6H4)}(CO)7](SiR3= SiPh34, SiEt35 and SiEtMe26). Structures are based on spectroscopic evidence and a XRD structure o
The clinical applicability of the revised McDonald diagnostic criteria of primary progressive multiple sclerosis (PPMS) was assessed in 17 patients with a longstanding PPMS diagnosis (mean 15 years). All patients were re-evaluated with clinical examinations, magnetic resonance imaging (MRI) of the brain and the spinal cord, extensive laboratory tests, and 12 patients underwent cerebrospinal fluid
Threshold stress, σth, for reorientation of hydrides in cold worked and stress-relieved (CWSR) Zr–2.5Nb pressure tube material was determined in the temperature range of 523–673 K. Using tapered gage tensile specimen, mean value of σth was experimentally determined by two methods, half thickness method and area compensation method. The difference between local values of σth measured across the thi
Protokoll Campus husstyrelse Närvarande Charlotta Johnsson Jerker Jacobsson Veronica Åberg Mozhgan Zachrison Anders Heyden Magdalena Unosson Magnus Svensson Lars Olsson Dick Lindroos Nathalie Regestad Jesper Strand Protokoll Sammanträdesdatum 2022-09-21 rektor, Campus Helsingborg admin. chef, utvecklingsenheten lokalansvarig, Inst f service management och tjänstevetenskap prefekt, Inst f strategis
https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2023-11/Husstyrelsen%202022-09-21%20protokoll.pdf - 2026-06-25
The evidence for the existence of a chemical mechanism in surface-enhanced resonance Raman scattering (SERRS) of rhodamine 6G (R6G) adsorbed on colloidal silver excited at 1064 nm is reported on the basis of experimental and theoretical analyses. A weak absorption peak at around 1060 nm for R6G-functionalized silver nanoparticles was observed, which is not present in the individual spectra of R6G
Background Few authors have investigated function and pain after surgical treatment of patients with bone metastases. In 1999 the Scandinavian Sarcoma Group (SSG) initiated the Skeletal Metastasis Registry as a multi-centric, prospective study to provide a scientific basis for recommendations of treatment. Patients and methods We have analyzed function and pain in 530 patients (mean age 65 yr) ope
A study on diffusion measurements of the protein lysozyme in liquids and agarose gels, at different pH and ionic strengths, has been performed using holographic laser interferometry. The measurements showed that the diffusive flux was very dependent on pH and ionic strength when the protein was not at its isoelectric point or when the charge of the lysozyme molecules was not screened by ions in th
Beslut Klarspråk Sida 1 av 3 Rektor BESLUT Diarienummer STYR 2024/1794 Datum 2024-09-05 Klarspråk: tillgängliga digitala texter Bakgrund Språklagens (2009:600) 11:e paragraf dikterar att ”språket i offentlig verksamhet ska vara vårdat, enkelt och begripligt”. Denna så kallade klarspråksparagraf innebär i praktiken att offentliga verksamheter är skyldiga att bedriva ett aktivt klarspråksarbete. Var
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Städer är nyckelarenor där sociala, ekonomiska och ekologiska samhällsutmaningar hanteras. Social inkludering och hållbar utveckling betraktas som två huvudutmaningar för europeiska samhällen och städer. Trots det saknas kunskap och forskning om hur städer hanterar potentiella konflikter och synergier mellan en politik för miljömässigt hållbara och socialt inkluderande samhällen. I det här projekt
Universitetslektor Kontaktinformation E-post: thomas [dot] pugh [at] mgeo [dot] lu [dot] se Mobil: +46 46 222 86 97Organisation Miljö- och geovetenskapliga institutionen (MGeo) Rumsnummer: 363 Hämtställe: 16 WebbplatsThomas Pughs profil i Lunds universitets forskningsportalAndra roller Universitetslektor Institutionen för naturgeografi och ekosystemvetenskap Medlem i Strategiskt forskningsområde B
https://www.nateko.lu.se/sv/thomas-pugh - 2026-06-25
Follow-up methods must be easy for young people to handle. We examine Interactive Voice Response (IVR) as a method for collecting self-reported data. Sixty inpatients were recruited from a child and adolescent psychiatric emergency unit in Malmö, Sweden and called every second (N = 30) or every fourth (N = 30) day from discharge until first visit in outpatient care. A pre-recorded voice asked them
Dijet angular distributions from the first LHC pp collisions at center-of-mass energy root s = 7 TeV have been measured with the ATLAS detector. The dataset used for this analysis represents an integrated luminosity of 3.1 pb(-1). Dijet chi distributions and centrality ratios have been measured up to dijet masses of 2.8 TeV, and found to be in good agreement with Standard Model predictions. Analys
Background and purpose. The purpose of this study was to evaluate the performance of gantry angle optimisation (GAO) compared to equidistant beam geometry for two inverse treatment planning systems (TPSs) by utilising the information obtained from a range of treatment plans. Material and methods. The comparison was based on treatment plans generated for four different head and neck (H&N) cance
