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Ultra-high-frequency ultrasound (UHFUS) has a reported potential to differentiate between aganglionic and ganglionic bowel wall, referred to as histoanatomical differences. A good correlation between histoanatomy and UHFUS of the bowel wall has been proven. In order to perform more precise and objective histoanatomical morphometrics, the main research objective of this study was to develop a compu
GJ 367 is a bright (V ≈ 10.2) M1 V star that has been recently found to host a transiting ultra-short period sub-Earth on a 7.7 hr orbit. With the aim of improving the planetary mass and radius and unveiling the inner architecture of the system, we performed an intensive radial velocity follow-up campaign with the HARPS spectrograph—collecting 371 high-precision measurements over a baseline of nea
A search for pair-produced vector-like quarks using events with exactly one lepton (e or μ), at least four jets including at least one b-tagged jet, and large missing transverse momentum is presented. Data from proton–proton collisions at a centre-of-mass energy of s= 13 TeV , recorded by the ATLAS detector at the LHC from 2015 to 2018 and corresponding to an integrated luminosity of 139 fb - 1 ,
Background: The ongoing Pan-European Real Life (PEARL) phase 4 study is evaluating fremanezumab effectiveness and safety for the prevention of episodic and chronic migraine. This interim analysis reports primary, secondary and exploratory endpoints from when 500 participants completed at least six months of treatment. Methods: Adults with episodic migraine or chronic migraine maintaining daily hea
Adjuvant bacillus Calmette-Guérin (BCG) instillations represent a cornerstone in the treatment of non–muscle-invasive bladder cancer. Instillation schedule and dose modifications have been evaluated in efforts to reduce the incidence of adverse events (AEs), but none so far has the same treatment efficacy as the full-dose recommended schedule. It has been shown that prophylactic quinolone use in c
Decentralized water reuse technologies are increasingly being explored as a transformative approach for complementing centralized water and wastewater infrastructure. A transition to onsite water reuse requires a better understanding of how urban infrastructures are governed. While governance tends to be discussed within ideal types─i.e., hierarchy, market, and network─researchers increasingly rec
Background and purpose: Early this century, the high risk strategy of primary stroke and cardiovascular disease (CVD) prevention for individuals shifted away from identifying (and treating, as appropriate) all at-risk individuals towards identifying and treating individuals who exceed arbitrary thresholds of absolute CVD risk. The public health impact of this strategy is uncertain. Methods: In our
This paper accounts for the development and initial validation of a yes/no vocabulary test of North Sámi called North Sámi Vocabulary Test (NSVT). North Sámi (NS) is an Indigenous language spoken in northern Scandinavia. Being an endangered language, NS is in need of revitalisation efforts. One contribution is the provision of proficiency assessment tools. We administered a 75-item NSVT version (5
Studies on patients with bladder outflow obstruction who have undergone surgery for benign prostatic hyperplasia, successfully relieving the obstruction, have revealed a persistence of storage symptoms associated with detrusor overactivity (DO) in 20% to 40% of patients. To study the underlying mechanisms, we have used a common rat model of obstruction/de-obstruction, assuming that non-voiding con
Introduction: Whether and under what conditions scientific knowledge provided by experts actually leads to political action is a question that academic research in various fields have focused on at length, without reaching a definitive answer. The position of expertise is especially delicate within the global environmental governance sphere containing multiple values, worldviews and epistemologica
Critical constructive feedback (CCF), is said to be a key ingredient in learning. However, if and how learners engage in CCF is rarely studied in collaborative learning situations. This study aims to filling this research gap by analyzing data logs from dyads of middle school students using an educational game in history, evaluating their inclination to dismiss or attend to feedback when making er
OBJECTIVE: An increasing number of human in vivo magnetic resonance imaging (MRI) studies have focused on examining the structure and function of the subfields of the hippocampal formation (the dentate gyrus, CA fields 1-3, and the subiculum) and subregions of the parahippocampal gyrus (entorhinal, perirhinal, and parahippocampal cortices). The ability to interpret the results of such studies and
ObjectivesThis study aimed to develop and externally validate a model for predicting insufficient future liver remnant (FLR) hypertrophy after portal vein embolization (PVE) based on clinical factors and radiomics of pretreatment computed tomography (CT)Patients and methodsClinical information and CT scans of 241 consecutive patients from three Swedish centers were retrospectively collected. One c
Observations of polarization position angle (θ) standards made from 2014 to 2023 with the High Precision Polarimetric Instrument (HIPPI) and other HIPPI-class polarimeters in both hemispheres are used to investigate their variability. Multiband data were first used to thoroughly recalibrate the instrument performance by bench-marking against carefully selected literature data. A novel co-ordinate
Objective: Women with current or previous drug use (WCPDU) have an increased risk of poor cervical and breast cancer outcomes, and low participation in screening for these cancer forms. The aim of this study was to assess self-reported barriers to and facilitators of cervical and breast cancer screening, among WCPDU. Methods: A survey based on results from a previous qualitative study about WCPDUs
Objective Systemic sclerosis Impact of Disease (ScleroID) is the first comprehensive patient-reported outcome measure (PROM) specifically developed for systemic sclerosis (SSc). We investigated the performance of ScleroID in patients with diffuse cutaneous SSc (dcSSc), as a prerequisite for its use in randomised controlled trials (RCTs) testing potentially disease-modifying drugs. Methods All pati
Background: Immune checkpoint inhibitors are now a part of the treatment arsenal for triple-negative breast cancer (TNBC) but refinement of PD-L1 as a prognostic and predictive biomarker is a clinical priority. We aimed to evaluate the relevance of novel PD-L1 immunohistochemical (IHC) thresholds in TNBC with regard to PD-L1 gene expression, prognostic value, tumor infiltrating lymphocytes (TILs),
Intermediate crops (ICs) are grown on large areas in Sweden and elsewhere for their function as cover or catch crops and to increase soil fertility, and they are usually soil-incorporated. The aim of this study was to investigate if aboveground biomass from ICs can be a sustainable source of biofuel feedstock. For that, the biomass yield of fertilized and unfertilized ICs was studied in field expe
Introduction Nutritional education intervention during pregnancy is the process of teaching pregnant women about the importance of a healthy diet and how to make healthy food choices. It is an important part of public health and vital to preventing adverse birth outcomes. Therefore, synthesising available evidence on the effect of nutritional education intervention on birth outcomes is essential f
