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BACKGROUND: Diesel engine exhaust causes adverse health effects. Meanwhile, the impact of renewable diesel exhaust, such as hydrotreated vegetable oil (HVO), on human health is less known. Nineteen healthy volunteers were exposed to HVO exhaust for 3 h in a chamber with a double-blind, randomized setup. Exposure scenarios comprised of HVO exhaust from two modern non-road vehicles with 1) no aftert
Aim: Early identification of patients at risk of serious adverse events (SAEs) is of vital importance, yet it remains a challenging task. We investigated the predictive power of National Early Warning Score (NEWS) 2, as compared to NEWS, among patients assessed by a Rapid response team (RRT).Methods: Prospective, observational cohort study on 898 consecutive patients assessed by the RRTs in 26 Swe
Background: Production of second-generation bioethanol and other bulk chemicals by yeast fermentation requirescells that tolerate inhibitory lignocellulosic compounds at low pH. Saccharomyces cerevisiae displays high plasticitywith regard to inhibitor tolerance, and adaptation of cell populations to process conditions is essential for reachingefficient and robust fermentations.Results: In this stu
Modelling tools used in impact assessment procedures can be regarded as tools for communication between science and policy. In order to create an integrated system for modelling not only the scientific components have to be in place but also the science/policy interfaces in the assessment procedures have to be identified and their social dynamics understood.To make a system like SEAMLESS Integrate
There is a long history of avian studies investigating the impacts of urbanization. While differences in several life-history traits have been documented, either between urban and rural populations or across generalized urbanization gradients, a detailed understanding of which specific environmental variables cause these phenotypic differences is still lacking. Here, we quantified several local en
The respiratory epithelium consists of multiple, functionally distinct cell types and is maintained by regionally specific progenitor populations that repair the epithelium following injury. Several in vitro methods exist for studying lung epithelial repair using primary murine lung cells, but isolation methods are hampered by a lack of surface markers distinguishing epithelial progenitors along t
Achieving CRISPR Cas9-based manipulation of mitochondrial DNA (mtDNA) has been a long-standing goal and would be of great relevance for disease modeling and for clinical applications. In this project, we aimed to deliver Cas9 into the mitochondria of human cells and analyzed Cas9-induced mtDNA cleavage and measured the resulting mtDNA depletion with multiplexed qPCR. In initial experiments, we fou
The breakup of the L-chondrite parent body (LCPB) in the asteroid belt at 466 Ma ago is the largest asteroid breakup documented in Earth's geological record for the past ca. three billion years. Recovery of abundant macroscopic fossil L chondrites in mid-Ordovician marine sediments as well as reconstructions of the flux of micrometeoritic chrome spinel through the ages have given much new informat
Översiktlig artikel om hur spanska sjukan 1918 drabbade Lunds universitet och särskilt dess studenter samt om hur vissa professorer i medicin förhöll sig till den nya smittan.
This research is triggered by the emerging ‘power by the hour’® paradigm, in which aero engines are effectively leased to airlines, with the manufacturing company remaining responsible for their maintenance and repair throughout their service life. By incorporating knowledge about the performance of existing products into the design phase of new products, it is hoped to tackle some of the in-servi
The problem of planning a trajectory for robots starting in an initial state and reaching a final state in a desired interval of time is tackled. We consider Model Predictive Control as an approach to the problem of point-to-point trajectory generation. We use the developed strategy to generate trajectories for transferring the state of the robot, fulfilling computational real-time requirements. E
Blind people may detect objects from the information in reflected sounds, echolocation. Detection as a function of the number of clicks compared to a continuous noise was tested by presenting clicks of 5 ms with rates from 1 to 64 clicks during a 500 ms period and a 500-ms continuous white noise. The sounds were recorded in an ordinary room through an artificial binaural head. The reflecting objec
