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To describe the Avodart after Radical Therapy for prostate cancer Study (ARTS), investigating the use of dutasteride (a dual 5 alpha-reductase inhibitor that suppresses intraprostatic dihydrotestosterone, reduces tumour volume and improves other markers of tumour regression in prostate cancer) to prevent or delay disease progression in patients with biochemical recurrence after therapy with curati
Att härleda ett internationellt illegalt handlande till en viss stat och hålla denna ansvarig är ett komplext problem i folkrätten. Det oklara rättsläget kompliceras ytterligare när aspekter av cyberoperationer introduceras med den snabba globala teknologiska utvecklingen. Rättsläget som det ser ut just nu är baserat på doktrin och sekundärrätt, där vikt läggs vid den tekniska bevisningen för att Attributing internationally wrongful acts to a particular State and liability is a complex problem in international law. The already unclear legal situation is further complicated when aspects of cyber operations are introduced with the rapid global technological development. To hold a State liable for the actions of non-State actors in cyberspace, we can only use secondary law and doctrine. The l
In Sweden, the food and agricultural sector is highly concentrated, especially in the food refinement and retail sectors, with a few major actors holding significant market power. This concentration poses challenges for smaller agri-food companies in Skåne, Sweden. This thesis aims to in depth exploring the challenges smaller agri-food companies face today. The thesis employs a case study approach
The situation for the environment is in many ways dire. However, amidst all the negative environmental developments it is easy to neglect the successes that have actually happened. With the aim of better understanding what factors facilitated such a success this thesis analyses one such case, namely emissions of dioxins and chlorinated waste from the pulp and paper industry in Sweden. Dioxins were
Popular Abstract in Swedish Svår alfa-1antitrypsinbrist (AAT-brist), s.k. PiZZ, är ett ärftligt tillstånd som har en hög förekomst i Sverige, cirka 1/1600. Bristen innebär ökad risk för utveckling av kroniskt obstruktiv lungsjukdom (KOL), speciellt hos rökare. Leversjukdom är också relativt vanlig och kan förekomma såväl i barndomen som i hög ålder. Levercirros (skrumplever) och levercancer är öveSevere alpha-1 antitrypsin deficiency (AATD) is a genetic disorder associated with increases risk of developing of chronic obstructive lung disease and liver disease. The Swedish National Registry for individuals with severe AATD was started 1991.Up to October 2008, a total of 1349 individuals were included in the registry. The aims of the studies in this thesis which bases on AATD registry are to
Popular Abstract in Swedish Sköldkörtelhormoner och bröstcancer Insjuknandet i sköldkörtelsjukdomar är liksom bröstcancer vanligast hos kvinnor efter klimakteriet och ett eventuellt samband har diskuterats i över ett sekel. Experimentella studier har visat att sköldkörtelhormoner påverkar både utveckling av normala bröstceller och tillväxt av bröstcancerceller. Det finns också belägg för att sköThyroid hormones and breast cancer-prospective studies on incidence, mortality and prognostic factors The aim of this thesis was to investigate in a prospective design, thyroid hormones in relation to breast cancer risk, mortality and prognostic factors. The association between total triiodothyronine (T3) levels and breast cancer risk was studied in 2185 women with146 incident breast cancer cas
A search is presented for the direct pair production of a chargino and a neutralino [Formula: see text], where the chargino decays to the lightest neutralino and the [Formula: see text] boson, [Formula: see text], while the neutralino decays to the lightest neutralino and the 125 GeV Higgs boson, [Formula: see text]. The final states considered for the search have large missing transverse momentum
The productivity of agricultural and forest ecosystems in regions at higher latitudes is to a large extent governed by low temperature and moisture conditions. Environmental conditions are acting both above- and below-ground and regulating carbon fluxes and evapotranspiration. However, the understanding of various feedbacks between vegetation and environmental conditions is still unclear. In this
Uppsatsen behandlar mäns våld mot kvinnor och beskriver hur fenomenet har utvecklats från att betraktas som en privat angelägenhet till ett samhällsproblem. Genom statliga satsningar för att motverka mäns våld mot kvinnor har ett målgruppsanpassat samverkanskoncept mellan myndigheter utvecklats, under samma tak i Malmö. På denna verksamhet ska de utsatta individernas behov sättas i fokus, vilket f
This study aims to gain a deeper understanding of how school counselors collaborate with social services in cases where children are suspected of being at risk. The focus is on how professional roles and power dynamics influence cooperation and decision-making processes. To address this purpose, the study explores the following research questions: How do school counselors and social services colla
Background and problem: In October 2010 the European Commission issued a Green Paper on Audit Policy in which they set out to draw lessons of the auditors’ role in the recent financial crisis. The European Commission considers the function of the audit to be a key contributor to investor confidence and suggests a number of controversial measures with the aim of ensuring financial stability in the
Med anledning av kammarrättens dom i mål nr 4468-19 av den 20 novem-ber 2020 har tidpunkten för när en ansökan om upptagande till handel ska anses vara inlämnad på den reglerade marknaden Nasdaq Stockholm, och således när marknadsmissbruksförordnigen (”MAR”) blir tillämplig i en noteringsprocess, fastställts till tidpunkten för när Nasdaq Stockholms Admission Form B lämnas in. Detta innebär i prakAs a result of the Swedish Administrative Court of Appeal’s judgment in case no. 4468-19 of 20 November 2020, the time for when an application for admission to trading shall be considered to have been submitted to the regulated market Nasdaq Stockholm, and thus when the market abuse regu-lation (“MAR”) becomes applicable in a listing process, has been decided to the time of submission of Nasdaq St
Denna studies syfte är att undersöka hur användare av plattformen TikTok uppfattar att kvinnliga ideal konstrueras på plattformen med ett fokus på det aktuella mediafenomet “Clean Girl”. Studien ämnar även att urskilja fenomenets eventuella påverkan på dess användare på både en samhällelig och individuell nivå. Vi har valt att utgå från en kvalitativ metod där vi med hjälp av fokusgrupper har inte
Cambodia is now facing alarming issues concerning occupational safety and health in the construction sector. According to the ILO, in 2009, every day four people in Cambodia were killed due to occupational accidents which this amounted to more than 1500 death of the construction workers. Based on the union leaders in Cambodia, those accidents and illnesses were seen and occurred at the constructio
China is a mega-diversity country with abundant natural resources, and the richness of these resources is demonstrated to be relevant with the local people’s historical interactions between biophysical and sociocultural systems. If we are to maintain biodiversity and strike a balance between human well-being and ecosystem service, it is important to incorporate the local people and their tradition
In England saltmarshes account for less than 0.5% of the land area, however they have a very high biodiversity value and provide significant economic and social worth. Climate change, continuous coastal urbanisation, and port development are a serious concern for coastal protection planners, city councils and the government. It is a challenge for these decision makers to balance the social, econom
Objective To explore healthcare providers’ perceptions of the current postpartum care (PPC) practice and its potential for improvement at governmental health institutions in low-resource suburbs in Dar es Salaam, Tanzania. Design Qualitative design, using focus group discussions (8) and qualitative content analysis. Setting Healthcare institutions (8) at three levels of governmental healthcare in
BACKGROUND AND OBJECTIVES: Degarelix is a gonadotropin-releasing hormone antagonist registered for the treatment of advanced hormone-dependent prostate cancer. Treatment causing androgen deprivation is associated with QT prolongation and this study investigated whether degarelix at supratherapeutic concentrations has an intrinsic effect per se on cardiac repolarisation and the QT interval.METHODS:
