Filtyp
Objective: To study if a modified triage system at an Emergency Department (ED) combined with educational efforts resulted in reduced time to antibiotics and decreased length of hospital stay (LOS) for patients with severe infection. Methods: A retrospective, observational study comparing patients before and after the start of a new triage model at the ED of a University Hospital. After the implem
Adult hippocampal neurogenesis is strongly impaired in Alzheimer's disease (AD). In several mouse models of AD, it was shown that adult-born neurons exhibit reduced survival and altered synaptic integration due to a severe lack of dendritic spines. In the present work, using the APPxPS1 mouse model of AD, we reveal that this reduced number of spines is concomitant of a marked deficit in their neur
Under 2012–2014 organiserade VIWAFU, ett nätverk för internationellt och interdisciplinärt forskarsamarbete i Norden och Baltikum, fyra seminarier för master-studenter, doktorander och post-docs. Var och ett av seminarierna hade ett tema, t.ex. VA-branschens reglering och styrning, infrastruktur för dricksvatten, innovativ utveckling inom kommunala vattenfrågor samt vattenhantering Viable Water Management and Governance for Futures (VIWAFU), a professional network for international and interdisciplinary collaboration amongst researchers from the Nordic and Baltic countries, was built for providing and sharing knowledge on water management and governance for future policy and decision making during the years 2012–2014. VIWAFU organized four workshops for MSc stud
Background: Smoking is reported to affect the risk of a number of chronic disorders, including rheumatic diseases. Previous cross-sectional studies have shown a lower frequency of smoking in patients with primary Sjögren's syndrome (pSS). The aim of this study was to investigate the impact of smoking and socioeconomic status on the risk of subsequent diagnosis of pSS in a nested case-control study
Background: Data are lacking from general population studies on how to define changes in lung function after bronchodilation. This study aimed to analyze different measures of bronchodilator response of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and slow vital capacity (SVC). Materials and methods: Data were derived from the Swedish Cardiopulmonary Bioimage Study (SCA
OBJECTIVE:: To compare the rates of abdominal surgery during pregnancy among women with previous bariatric surgery (women in the case group) and women with first-trimester body mass index (BMI) greater than 35 and no previous bariatric surgery (women in the control group). METHODS:: We conducted a national cohort study, merging data from the Swedish Medical Birth Registry and the Swedish National
Background: The glomerular filtration rate (GFR) is the most important measure of kidney function and chronic kidney disease (CKD). This study aims to validate commonly used equations for estimated GFR (eGFR) based on creatinine (cr), cystatin C (cys), β-trace protein (BTP), and β2-microglobulin (B2M) in older adults. Method: We conducted a validation study with 126 participants aged between 72 an
Background: There is a need for a prehospital stroke test that in addition to high sensitivity for stroke, also is able to communicate stroke severity similar to the National Institute of Health Stroke Scale (NIHSS). Methods: The PreHospital Ambulance Stroke Test (PreHAST), an eight item test based on NIHSS, which scores stroke severity from 0-19 points, was designed and adapted for the ambulance
Background/Aims: Men with terminal renal failure are often infertile. Anti-müllerian hormone (AMH), a marker of Sertoli cell function, is decreased among men with chronic kidney disease (CKD). Recently, a microRNA, miR-155, has been shown to be a potential marker for subfertility. We studied miR-155 and semen parameters in patients with CKD who were not yet on dialysis. We also aimed to study poss
Objective: Healthcare professionals (HCPs) are required to assess and train patients in the correct use of inhalers but are often unable to demonstrate correct technique themselves. We sought to assess the level of training required for HCPs to master and maintain device mastery when using two different dry powder inhalers (DPIs). Methods: We conducted a randomized, un-blinded, crossover study in
The present study aims at exploring the influence of voice quality on listening effort in children performing a language comprehension test with sentences of increasing difficulty. Listening effort is explored in relation to gender ( = cisgender). The study has a between-groups design. Ninety-three mainstreamed children aged 8;2 to 9;3 with typical language development participated. The children w
Purpose: A gold standard for evaluation of aesthetic outcome after breast-conserving therapy (BCT) is still lacking. The BCCT.core software has been developed to assess aesthetic result in a standardised way. We aimed to study how the result of BCCT.core after BCT is associated with quality of life, measured with the BREAST-Q™, a validated questionnaire. Methods: Women eligible for BCT were consec
Background: To investigate the risk of first-time acute coronary syndrome (ACS), stroke and venous thromboembolism (VTE) in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) and undifferentiated spondyloarthritis (uSpA), compared to each other and to the general population (GP). Methods: This is a prospective nationwide cohort study. Cohorts with AS (n = 6448), PsA (n = 16,063)
We studied the relative contribution of each sex and total effort expended in feeding nestlings in the great tit Parus major in relation to artificially altered brood size. A recent model suggests that feeding frequency should reflect the optimal trade-off between parental and fledgling survival, the former being negatively, the latter positively, influenced by high feeding frequencies. In both se
This study reports an aviary experiment aimed at determining what affects social dominance in the great tit (Parus major), especially why older birds (adults) in nature normally dominate younger ones (juveniles). When birds were matched with respect to age, prior residency determined dominance. Without a difference in prior residency older birds dominated younger ones. However, when juvenile birds
A cross-fostering experiment demonstrated that tarsus length of European starlings (Sturnus vulgaris) was heritable. The tarsus length of the foster-parent had no effect. A full-sib resemblance analysis showed that sibs were much more similar in tarsus length than explained by heritability alone. This was partly due to an effect of female mating status on offspring tarsus length. When nestling gro
In this paper we show that nestling mass hierarchies in the European Starling (Sturnus vulgaris) are due to asynchronous hatching. The parents may, by starting to incubate the day the penultimate egg is laid, or earlier, affect the degree of hatching asynchrony and thereby the nestling weight hierarchy. Intra-clutch variation in egg size had no effect on nestling weight hierarchies, explaining onl
