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3-Bromo-2-(bromomethyl)propyl (dibromoisobutyl or DIB) mono- to tetrasaccharide glycosides were prepared in moderate to high yields by treatment of the corresponding 1-0-acetyl saccharides with 3-bromo-2-(bromo-methyl)propanol (DIBOL) and boron trifluoride etherate. Treatment of the DIB glycosides with alkyl- and ω-methoxycarbonylalkyl thiols gave the corresponding bis-sulfide glycolipids and spac
Type 2 diabetes (T2D) is a polygenic disease and studies to understand the etiology of the disease have required selectively bred animal models with polygenic background. In this review, we present two models; the Goto-Kakizaki (GK) rat and the Oikawa-Nagao Diabetes-Prone (ON-DP) and Diabetes-Resistant (ON-DR) mouse. The GK rat was developed by continuous selective breeding for glucose tolerance f
A meshless collocation method based on radial basis function (RBF) interpolation is presented for the numerical solution of Maxwell's equations. RBFs have attractive properties such as theoretical exponential convergence for increasingly dense node distributions. Although the primary interest resides in the time domain, an eigenvalue solver is used in this paper to investigate convergence properti
The ATLAS physics program at the High Luminosity LHC (HL-LHC) calls for a precision in the luminosity measurement of ±1%. A larger uncertainty would represent the dominant systematic error in some precision measurements, including the Higgs sector. To fulfil such requirement in an environment characterized by up to 140 simultaneous interactions per bunch crossing (200 in the ultimate scenario), AT
BackgroundResting pulse is robustly and inversely associated with the risk for externalizing disorders and may be positively associated with internalizing disorders. We know little about the causal nature of these associations.MethodsWe examined resting pulse at conscription examination in 369 301 males born 1960-80 with a mean (s.d.) follow-up of 29.1 (7.7) years. From pulse rates, we predicted,
Viable city logistics are built on a sound business model that considers the financial viability and performance, and the role of externalities and stakeholders. To this end, the purpose of this dissertation is to increase understanding of how a business model can contribute to achieving viable city logistics initiatives.The research presented is qualitative and consists of three studies and five
Accidents nearby work zones are a persistent road safety problem in many European countries. The Conference of European Directors of Roads (CEDR) has initiated and finances the IRIS project (Incursion Reduction to Increase Safety in road work zones) with the aim to collect and share information about best practices in temporary traffic management at road works. An analysis of work zone accidents a
Marine mammals and coastal fisheries are two features commonly associated with thriving marine environments, but it is also a case of wildlife impact on human interests. This paper analyses the seal-fisheries encounter in a Swedish Baltic Sea fishery. The problem concerns seals eating fish from the fishing gear which causes considerable economic losses to small-scale fishermen. This mixed-method s
A Soft X-ray FEL (the SXL) is currently being designed at the MAX IV Laboratory. In the work to adapt the FEL to the scientific cases several advanced options are being studied for coherence enhancement, generation of short pulses and two-color pulses. We will discuss the current status and initial results of the schemes studied, especially regarding the FEL performance with the features of the MA
BACKGROUND: The objective of the Swedish cleft lip and palate (CLP) registry is to promote quality control, research and improvement of treatment, by comparison of the long-term results of surgery, orthodontics and speech from all six Swedish CLP centres. The purpose of the study was to investigate the coverage and reporting degree of the Swedish CLP registry, and to describe the design of the reg
Recent data resulting from studies of two-nucleon transfer reaction on 11Li, analyzed through a unified nuclear-structure-direct-reaction theory have provided strong direct as well as indirect confirmation, through the population of the first excited state of 9Li and of the observation of a strongly quenched ground state transition, of the prediction that phonon-mediated pairing interaction is the
Mafic dykes and dyke swarms in continental settings provide information on the evolution of the subcontinental mantle and can be key elements in the reconstruction of paleo-geographic settings of now separated crustal terranes. This study focuses on the petrogenesis and geochronology of mafic dykes of the WNW (~125°) trending Bhanupratappur swarm in the central Bastar Craton, central India. Dykes
The provision and administration of high quality urban public green spaces intertwines issues of planning, design, management and maintenance with governance. The benefits of such spaces are often tied to social justice, public health and recreation, biodiversity and helping cities to deal with climate change. International policies and changes in public administration have encouraged user partici
Smart cyber-physical systems (S-CPSs) are complex engineered systems empowered by cyber-physical computing and equipped with the capability of reasoning, learning, adapting, and evolving. As an outcome of data-driven dynamic computing, reasoning capabilities, and the run-time obtained own knowledge, nonlinear and emergent behavior of S-CPSs whilst in operation is an open issue, not experienced in
A search for the production of three massive vector bosons in proton–proton collisions is performed using data at s=13 TeV recorded with the ATLAS detector at the Large Hadron Collider in the years 2015–2017, corresponding to an integrated luminosity of 79.8 fb−1. Events with two same-sign leptons ℓ (electrons or muons) and at least two reconstructed jets are selected to search for WWW→ℓνℓνqq. Eve
