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Background: Galectins are a group of carbohydrate-binding proteins that are involved in neoplastic development and progression. In a previous mass spectrometry-based study, we identified galectin 4 as a down-regulated protein in short-term survivors of pancreatic cancer. This study was performed to validate the prognostic value of galectin 4 in a larger cohort of pancreatic cancer patients undergo

The antimicrobial peptide LL-37 is anti-inflammatory and proapoptotic in human periodontal ligament cells. J Periodont Res 2011; doi: 10.1111/j.1600-0765.2011.01436.x. © 2011 John Wiley & Sons A/S Background and Objective: The antimicrobial peptide LL-37 is expressed in periodontal tissue, and variations in LL-37 levels have been associated with periodontal disease. The effects of LL-37 on per

In skin, hemidesmosomal protein complexes attach the epidermis to the dermis and are critical for stable connection of the basal epithelial cell cytoskeleton with the basement membrane (BM). In muscle, a similar supramolecular aggregate, the dystrophin glycoprotein complex links the inside of muscle cells with the BM. A component of the muscle complex, dystroglycan (DG), also occurs in epithelia.

The study can statistically certify that there exists a negative relationship between EV/EBIT-ratio and returns among stocks on the OMX Copenhagen Exchange between 2011-2021. It can also be concluded that EV/EBIT should not be used as the single factor when making investment decisions due to a low r-squared value. Portfolios consisting of low EV/EBIT companies managed to outperform high EV/EBIT po

Prominent in the sky, but not visible to humans, is a pattern of polarized skylight formed around both the Sun and the Moon. Dung beetles are, at present, the only animal group known to use the much dimmer polarization pattern formed around the Moon as a compass cue for maintaining travel direction. However, the Moon is not visible every night and the intensity of the celestial polarization patter

In this paper we argue that the emergence of the dominant model of university organization, which is characterized by a large agglomeration of many (often loosely affiliated) small research groups, might have an economic explanation that relates to the features of the scientific production process. In particular, we argue that there are decreasing returns to scale on the level of the individual re

BACKGROUND AND PURPOSE: The breast cancer susceptibility genes BRCA1 and BRCA2 interact with Rad51, one of the central components in the homologous recombination repair pathway. This study evaluates the prognostic and predictive role of BRCA1, BRCA2 and Rad51, individually and as a complex, in breast cancer.MATERIALS AND METHODS: Expression of BRCA1, BRCA2 and Rad51 was investigated using immunohi