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Summary. The optimal mode of delivery of a haemophilia carrier expecting a child is still a matter of uncertainty and debate. The aim of this commentary/review is to suggest that normal vaginal delivery should be the recommended mode of delivery for the majority of carriers, based on review of studies on obstetric aspects of haemophilia. About 2.0-4.0% of all haemophilia boys born in countries wit
Human cystatin C is considered the physiologically most important inhibitor of endogenous papain-like cysteine proteases. We present here an unexpected function of cystatin C. Instead of acting as an inhibitor, cystatin C acts as a facultative, endogenous cofactor for the papain-like IgG-cleaving enzyme IdeS of the human pathogen Streptococcus pyogenes. IdeS activity is not dependent on cystatin C
Professor Kontaktinformation E-post: tomas [dot] hellstrom [at] fek [dot] lu [dot] se Telefon: +46 46 222 80 27Organisation Strategi Rumsnummer: Alfa 5,6 rum B423 Hämtställe: 10 WebbplatsTomas Hellströms profil i Lunds universitets forskningsportalAndra roller Facklig förtroendeman ST vid Lunds universitet Professor CIRCLE Publikationer Visar av publikationer. Sorterade efter år och sen titel. Fil
https://www.ehl.lu.se/tomas-hellstrom - 2026-07-17
The construction sector provides the direct means to the development and expansion of economic activities, but is at the same time a major consumer of physical and natural resources and a polluter of the environment. Over the last decades, the environmental impact of construction activities has grown dramatically due to the increase in the world population and greater industrial and human activity
We examine the case of Denmark - a country which historically had next to no domestic energy resources - for which we present new historical energy accounts for the years 1800-1913. We demonstrate that Denmark’s take off at the end of the nineteenth century was relatively energy dependent. We relate this to her well-known agricultural transformation and development through the dairy industry, and
Oncogenic c-Kit mutations have been shown to display ligand-independent receptor activation and cell proliferation. A substitution of aspartate to valine at amino acid 816 (D816V) is one of the most commonly found oncogenic c-Kit mutations and is found in >90% of cases of mastocytosis and less commonly in germ-cell tumors, core-binding factor acute myeloid leukemia and mucosal melanomas. The mecha
Metal-halide perovskite semiconductors are certainly one of the hottest topic in solar energy conversion. Optimization of both the absorber material and device architecture has led to an astoundingly rapid increase in the reported device efficiencies. Initially developed in the context of dye-sensitized solar cell research, metal-halide perovskite devices now reach efficiency values and hence need
Enzymes play a key role in almost all biological processes, accelerating a variety of metabolic reactions as well as controlling energy transduction, the transcription, and translation of genetic information, and signaling. They possess the remarkable capacity to accelerate reactions by many orders of magnitude compared to their uncatalyzed counterparts, making feasible crucial processes that woul
This article explores the emergence of PV adoption practices among non-residential property owners in Sweden to deepen insights into PV diffusion and accelerate a renewable electricity transition. It applies a social practice theory approach to show how different practice elements need to come together to establish a PV adoption practice.Twenty-five semi-st
Kraft lignin is an underutilized resource from the pulp and paper industry with the potential of being a key raw material for renewable fuels and chemicals. The separation of high-molecular-weight lignin from black liquor by ultrafiltration has been widely investigated, while the permeate containing low-molecular-weight lignin has received little attention. Nanofiltration can concentrate the low-m
PurposeThe purpose of this paper is to analyse the impact of six energy consumption factors (unsold products, product returns, packaging, freight transport, passenger transport and buildings) on the total energy consumption in three types of distribution channels for e-commerce and conventional trade.Design/methodology/approachThe study uses a quantitative calculation model where input data for th
Despite new energy-efficient technologies in buildings, discrepancies between predicted and actual energy use continue to occur, mainly due to the complexity and variability of users' behaviour(s). Users' interactions with energy-efficient solutions need to be studied holistically to better understand the complexity of their behaviour. This systematic literature review was conducted to identify wh
This study focuses on the introduction of new nuclear, particularly Small Modular Reactors (SMRs) in Sweden. The Swedish Government has decided on a revival for nuclear energy where SMRs are an important contribution to reach the goal of a total output of at least 2 500 MW by 2035. In this stage when much is unclear about the re-introduction and SMRs are under development media is an important age
In the pursuit of CO₂-neutral renewable energy solutions, biofuels have emerged as one of the key strategies. However, biodiesel production generates a surplus of crude glycerol (GL), creating a need for efficient valorization pathways. The conversion of GL into value-added chemicals represents a sustainable approach to address this issue. Metal nanoclusters (NCats) embedded within metal-organic f
A simple and efficient approach for profiling the greenness of high performance liquid chromatography (HPLC) methods is presented. This environmental assessment tool (EAT) takes into consideration the environmental, health and safety issues for all solvents involved in the chromatographic method, and calculates a total score that can be used for comparison of the greenness of different methods. A
Developing countries are giving increasing attention to industry development in renewable energy industries. Previous research highlights the influence of technology characteristics on such catching-up policies, distinguishing between complex products produced in small batches, and mass-produced simple products. We suggest that catching-up policies should move beyond this binary distinction betwee
