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Personlig assistans i praktiken : Beredskap initiativ och vänskaplighet

Popular Abstract in Swedish Personlig assistans i praktiken Beredskap, initiativ och vänskaplighet Bakgrund, syfte och perspektivval Denna avhandling handlar om hur det går till att realisera personlig assistans, en insats för människor med omfattande funktionsnedsättningar. Serviceformen personlig assistans, som myntades av den amerikanska Independent Living –rörelsen i slutet av 1960 talet, uPersonal assistance is a user-directed service that was founded by a section of the disability movement, namely the American Independent Living movement, in the late 1960s. Today, the concept and ideology of personal assistance services (PAS) has spread worldwide, and constitutes a part of the support system for people with disabilities in many countries. The service differs from several other pub

Cobalt-mediated solid phase synthesis of 3-O-alkynylbenzyl galactosides and their evaluation as galectin inhibitors

Methyl beta-D-galactoside was converted to the corresponding 3,4-O-stannylene acetal, which was selectively benzylated with 3-iodobenzyl bromide and coupled to a polymer-bound propargylic ether via a Sonogashira reaction. The polymer-bound carbohydrate substrate was cleaved from the resin with different carbon nucleophiles in a cobalt-mediated Nicholas reaction. The product 3-O-alkynylbenzyl galac

Nonlinear harmonic generation in free-electron laser oscillators

Nonlinear harmonic generation has been described theoretically, and observed, in free-electron laser (FEL) amplifiers. The mechanism relies on the nonlinear, higher-order bunching when the fundamental reaches high intensities, and can also be expected in high-power FEL oscillators. We use the 3D polychromatic simulation code MEDUSA to study the nonlinear harmonic generation in FEL oscillators. Str

Should the acceptable noise level be considered to be an acceptable noise range?

The acceptable noise level (ANL) test is used to quantify the amount of competing background noise (BNL) that a listener is willing to accept when listening to speech at the most comfortable level (MCL). ANL is calculated by subtracting the BNL from the MCL. Most studies show large intersubject ANL variability and a few also demonstrate large intrasubject variability. Very few predictor variables

Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells.

Several microbial pathogens have been reported to interact with glycosaminoglycans (GAGs) on cell surfaces and in the extracellular matrix. Here we demonstrate that M protein, a major surface-expressed virulence factor of the human bacterial pathogen, Streptococcus pyogenes, mediates binding to various forms of GAGs. Hence, S. pyogenes strains expressing a large number of different types of M prot

Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83?000 women with breast cancer from 16 countries

BACKGROUND: The Collaborative Group on Hormonal Factors in Breast Cancer has brought together the worldwide epidemiological evidence on the possible relation between breast cancer and previous spontaneous and induced abortions. METHODS: Data on individual women from 53 studies undertaken in 16 countries with liberal abortion laws were checked and analysed centrally. Relative risks of breast cancer

The solar neighborhood age-metallicity relation - Does it exist?

We test the hypothesis that the spread in the age-metallicity plot of the solar neighborhood is due to a mixture of stars belonging to kinematically different sub-populations of the Galactic disk, i.e., the thin and the thick disk. We use a kinematic subsample of similar to 600 stars from a sample of similar to 6000 dwarf and subgiant stars from the Hipparcos catalog. All of these stars have a ful