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γ-aminobutyric acid and taurine release in the striatum of the rat during hypoglycemic coma, studied by microdialysis

Extracellular levels of striatal γ-aminobutyric acid (GABA) and taurine were monitored during insulin-induced hypoglycemia using microdialysis. At the onset of isoelectricity in the electroencephalogram (EEG), a transient 5-fold increase in the levels of GABA occurred. Taurine levels increased 5 min following the onset of isoelectricity and continued to increase during the entire isoelectric perio

Svenska rådet för HLR ska öka överlevnaden vid hjärtstopp

It is estimated that about 30 000 people a year are successfully resuscitated after having suffered an out-of-hospital cardiac arrest in Europe. The number of patients that are successfully resuscitated after an in-hospital cardiac arrest is not known, but it can be assumed that this figure is even higher than that after an out-of-hospital cardiac arrest. The aim of the Swedish Resuscitation Counc

Enzymatic peptide synthesis in organic media : a comparative study of water-miscible and water-immiscible solvent systems

Peptide synthesis was carried out in a variety of organic solvents with low contents of water. The enzyme was deposited on the support material, celite, from an aqueous buffer solution. After evaporation of the water the biocatalyst was suspended in the reaction mixtures. The chymotrypsin-catalyzed reaction between Z-Phe-OMe and Leu-NH2 was used as a model reaction. Under the conditions used ([Z-P

Potential Rebound Effects of 1.5° Lifestyles

Understanding how lifestyles should and could change to meet the terms of the Paris Agreement is the aim of the project ‘EU 1.5° Lifestyles’. It focuses on lifestyle options compatible with a 1.5°C target and explores the structural barriers and enablers to implementing these. Many of these lifestyle options relate to circular strategies such as sharing, reusing and repairing products.However, eve

"but at this disjuncture we know what is what" : Kevin Beasley, Banu Cennetoğlu, John Greyson, Amy Ching-Yan Lam, Ghislaine Leung, Sara Leydon, Mahshid Rafiei

Cuttings of text and image come together to form Sara Leydon’s Baroness de Lancinena (1990) and Alice Kyteler (1990). Each a reference to a woman either identified or accused of practicing witchcraft, these two collages are part of a series first shown in a 1990 solo exhibition titled Conviction at Artspeak. Their history in this city is considerable, living long-term in the collection of Christos

The Role of Repair as a Resource for Resilience : Case Studies on the Effects of Repair Outcomes of Essential Products

In both the US and EU, policymakers and government agencies are acknowledging theimportance of having access to repair options, particularly for vulnerable product users who depend on their products. As such, repair can play an important role as a resource for resilience, but research is missing. We propose that repair can act as a resource for resilience. A comprehensive, structured way to unders

Narrow and broad functions of negation in a miniature artificial language

Negated forms have been shown to cause a higher processing cost for language comprehension in the form of higher error rates and longer processing times. Studies that tested prefixal negation (e.g. unhappy) found conflicting results as to whether these forms are processed as negated forms or as single lexical items without any processing cost (Hoosain, 1973; Sherman, 1976, 1973). The present study

AI-Driven Drug Response Prediction for Personalized Cancer Medicine

Artificial intelligence (AI) has been used to develop drug sensitivity prediction models, raising the opportunity of using it for personalized cancer medicine. This chapter describes recent advancements in drug response prediction methods using machine learning algorithms. Pharmacogenomic datasets come with different types of biological data including genetic mutations, gene expression, copy numbe

Customisable 3D printed microfluidics for integrated analysis and optimisation

The formation of smart Lab-on-a-Chip (LOC) devices featuring integrated sensing optics is currently hindered by convoluted and expensive manufacturing procedures. In this work, a series of 3D-printed LOC devices were designed and manufactured via stereolithography (SL) in a matter of hours. The spectroscopic performance of a variety of optical fibre combinations were tested, and the optimum path l

Environmental Rights of Indigenous Peoples in Post-Conflict

The paper examines the legal framework protecting the rights of indigenous peoples in post-conflict and whether the latest session of the International Law Commission (2016) has contributed to progressively expand this framework. The Special Rapporteur for the topic Protection of the Environment in relation to Armed Conflict suggested in her third report that the Commission should adopt a draft pr

Arsenic adsorption by iron-aluminium hydroxide coated onto macroporous supports : Insights from x-ray absorption spectroscopy and comparison with granular ferric hydroxides

The arsenic adsorption characteristics of a macroporous polymer coated with coprecipi-tated iron-aluminium hydroxides (MHCMP) is evaluated in this study. The MHCMP had a maximum adsorption capacity of 82.3 and 49.6 mg As/g adsorbent for As(III) and As(V) ions respectively. Extended X-ray Absorption Fine Structure (EXAFS) confirmed that binding of As(III) ions took place on the iron hydroxides coat

Syntactic Representations Considered for Frame-Semantic Analysis

We address the question of which syntactic representation is best suited for FrameNet-based semantic analysis of English text. We compare analyzers based on dependencies and constituents, and a dependency syntax with a rich set of grammatical functions with one with a smaller set. Our study demonstrates that dependency-based and constituent-based analyzers give roughly equivalent performance, and

Fluorescence polarization as an analytical tool to evaluate galectin-ligand interactions.

Galectins are a family of β-galactose binding lectins associated with functions such as immunological and malignant events. To study the binding affinity of galectins for natural and artificial saccharides and glycoconjugates we have developed an assay using fluorescence polarization. A collection of fluorescein-conjugated saccharides was synthesized and used as probes with galectins-1 and -3 and

Never My Daughters: A Qualitative Study Regarding Attitude Change Toward Female Genital Cutting Among Ethiopian and Eritrean Families in Sweden

To explore attitudes toward female genital cutting (FGC) in a migration perspective, qualitative interviews were conducted with men and women from Ethiopia and Eritrea in Sweden. We found firm rejection of all forms of FGC and absence of a guiding motive. Informants failed to see any meaning in upholding the custom. We conclude that children of Ethiopian or Eritrean parents resident in Sweden run