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Perspectives on MOOC Quality-An account of the EFQUEL MOOC Quality Project

Massive Open Online Courses (MOOC) represent a recent stage in open education. In more and more institutions they are moving from an early entrepreneurial stage into the reality. The rapidly rising participation levels, high visibility and a growing community worldwide prompt a number of important questions. The MOOC Quality Project, an initiative of the European Foundation for Quality in E-Learn

Modelling significant wave height in the North Atlantic

The surface of the ocean, and so such quantities as the significant wave height, can be thought of as a random surface in space which develops over time. In this paper, we explore certain types of random fields (in space and time) as models for the significant wave height and fit these models to data obtained from the TOPEX-Poseidon satellite. The data consist of observations along different one-d

Inhibition of Galectins with Small Molecules

Evidence that the galectin family of proteins plays crucial roles in cancer, inflammation, and immunity has accumulated over the last decade. The galectins have consequently emerged as interesting drug targets. A majority of galectin functions occurs by means of cross-linking glycoproteins and by doing so controlling gly-coproteirl cellular localization and residence times. The glycoprotein cross-

Kristina Fjelkestam, Det sublimas politik: emancipatorisk estetik i 1800-talets konstnärsromaner

The review of Kristina Fjelkestam’s Det sublimas politik: emancipatorisk estetik i 1800-talets konstnärsromaner [Sublime politics: emancipatory aesthetics in nineteenth-century Künstlerromane] focuses on how the author makes use of the sublime as a means to connect three women writers use of the Künstlerromane in their political, emancipatory projects. On the other hand, the review also deals with

Bracketing the Age of Magmatic-Hydrothermal Activity at the Cerro de Pasco Epithermal Polymetallic Deposit, Central Peru: A U-Pb and Ar-40/Ar-39 Study

The Cerro de Pasco epithermal Cordilleran base metal deposit in central Peru consists of two mineralization stages which are spatially and genetically related to a mid-Miocene diatreme-dome complex. In order to constrain the duration of the magmatic-hydrothermal system at Cerro de Pasco, U-Ph age determinations and Hf isotope determinations have been conducted on single zircon grains. Biotite from

Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3.

Rational drug design is predicated on knowledge of the three-dimensional structure of the protein-ligand complex and the thermodynamics of ligand binding. Despite the fundamental importance of both enthalpy and entropy in driving ligand binding, the role of conformational entropy is rarely addressed in drug design. In this work, we have probed the conformational entropy and its relative contributi

Andean Speciation and Vicariance in Neotropical Macrocarpaea (Gentianaceae-Helieae)

The pains Macrocarpaea (Griseb.) Gilg (Gentianaceae. Helieae) is among the largest woody genera of tropical gentians, with most of its species occurring in the wet mountainous forest., of the Andes. Phylogenetic and dispersal-vicariance analyses (DIVA) of 57 of the 105 currently recognized species in the genus. Using two data sets front nuclear DNA (ITS and 5S-NTS sequences) and morphology. show i

Måltiden en het potatis för barnfamiljer

Måltiderna ska lösas intellektuellt, praktiskt och emotionellt. Flera gånger varje dag. Hur hittar unga familjer matinspiration under vardagens tidspress? Och hur klarar de vardagens ”hot spot” mellan 17 och 18? Att handla mat och komponera vardagens måltider är en ständigt pågående problemlösningsprocess. Den som har ansvaret behöver idéer, inte alltid nyskapande och dramatiska, men ändå någon

Markov Regime Switching in Economic Time Series

Popular Abstract in Swedish Avhandlingens bidrag ligger inom området för Markov regimskiftesmodeller i tidsserieanalys. Den består av fem separata uppsatser som specifikt undersöker två statistiska frågeställningar, samt applicerar metodologin på fyra olika makroekonomiska områden. De två huvudsakliga statistiska bidragen rör (i) utvecklandet av ett flexibelt test baserat på simulering för att utrThis dissertation studies statistical properties and applications of the Markov switching models for economic time series in five separate papers. The two main statistical themes are (i) the task of choosing the number of states to use in the model, and (ii) inference on time-varying transition probabilities. Our empirical applications span a wide array of topics in international finance and macro

I vilken utsträckning kan elcyklar (och elmopeder) ersätta dagens biltrafik?

Gruppen om använder elcykel är enligt datamaterialet främst män med tillgång till bil. Innehavet är ganska jämnt fördelat över 35 år. Elcyklisterna är teknikintresserade samtidigt verkar miljöintresset vara ett drivande motiv till varför elcykel införskaffades. Minskad restid verkar ha en viss betydelse speciellt för den yngre åldersgruppen. Majoriteten av de svarande instämmer i påståendet att el

Influence of fiber degradation and concentration of fermentable sugars on simultaneous saccharification and fermentation of high-solids spruce slurry to ethanol

Background: Saccharification and fermentation of pretreated lignocellulosic materials, such as spruce, should be performed at high solids contents in order to reduce the cost of the produced bioethanol. However, this has been shown to result in reduced ethanol yields or a complete lack of ethanol production. Previous studies have shown inconsistent results when prehydrolysis is performed at a high

Computational Aero-acoustics of the coaxial flow exhaust system of gas turbine engine

Jet engine noise is an environmental problem that needs to be addressed. Several methods to reduce the jet noise have been proposed in the last decades. The main issue is to find methods that reduce noise without causing considerable loss of thrust. Experimental and computational tools are mandatory in successfully reducing jet engine noise emissions. One of the challenging issues of computing the

Pressure Sensitivity of HCCI Auto-Ignition Temperature for Oxygenated Reference Fuels

The current research focuses on creating a homogeneous charge compression ignition (HCCI) fuel index suitable for comparing different fuels for HCCI operation. One way to characterize a fuel is to use the auto-ignition temperature (AIT). The AIT can be extracted from the pressure trace. Another potentially interesting parameter is the amount of low temperature heat release (LTHR) that is closely c

CEFLE and Direkt Profil: a new computer learner corpus in French L2 and a system for grammatical profiling

Abstract in UndeterminedThe importance of computer learner corpora for research in both second language acquisition and foreign language teaching is rapidly increasing. Computer learner corpora can provide us with data to describe the learner's interlanguage system at different points of its development and they can be used to create pedagogical tools.In this paper, we first present a new computer

Attentatet på Dramaten. En studie av Alf Sjöbergs uppsättning av Marika Stiernstedts drama. The Outrage at the Royal Dramatic Theatre in Stockholm. A studie of Alf Sjöberg's stageing of Marika Stiernstedt's drama.

Popular Abstract in Swedish Avhandlingen behandlar den svenska författarinnan Marika Stiernstedts drama Attentatet och regissören Alf Sjöbergs uppsättning av det på Dramaten 1944. Produktionsprocessen följs från dramats tillkomst till uppsättningens möte med publiken. Avhandlingen undersöker vad dramat och uppsättningen berättar om tidens oro och om politiska och etiska motsättningar. Fokus liggerThe thesis deals with the Swedish author Marika Stiernstedt's drama The Outrage and Alf Sjöberg's production of it at the Royal Dramatic Theatre in 1944. The production process is followed from the birth of the drama to the production's encounter with the audience. The thesis examines what the drama and the production tell about the unrest of those times and about political and ethical antagonisms

On Computational Heat Transfer in Industrial Applications

Industrial energy systems involve many components where fluid flow, heat and mass transfer are the important transport processes. For design and development as well as investigation of innovative ideas, computational methods are of vital importance. Since the early pioneering works (by, e.g., the Spalding group) in the 1960s and 1970s, the development has been tremendous and nowadays CFD (computat