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BACKGROUND: Cell membrane interactions rely on lipid bilayer constituents and molecules inserted within the membrane, including specific receptors. HAMLET (human alpha-lactalbumin made lethal to tumor cells) is a tumoricidal complex of partially unfolded alpha-lactalbumin (HLA) and oleic acid that is internalized by tumor cells, suggesting that interactions with the phospholipid bilayer and/or spe
Anti-phospholipid (aPL) antibodies are important contributors to development of thrombosis in patients with the autoimmune rheumatic disease systemic lupus erythematosus (SLE). The underlying mechanism of aPL antibody-mediated thrombosis is not fully understood but existing data suggest that platelets and the complement system are key components. Complement activation on platelets is seen in SLE p
The Energy using products (EuP) directive proposed by the European Commission is often referred to as "the first Integrated Product Policy (IPP) directive". The main purpose of the directive is to ensure the free movement of EuP in the internal market as well as to improve the environmental performance of products throughout their life cycle. Product groups likely to be addressed through the direc
Galectins, a lectin family, have shown binding affinities towards b-galactosides. Galectins have been proposed to be involved in a wide range of functions like for example, cell growth, adhesion, migration, chemo taxis and apoptosis. They have also been associated with various cancer types. However, the detailed functions of galectins are still very much unknown. High affinity inhibitors towards t
The question of the relation between the collective and the individual has had a long but patchy history within both philosophy and psychology. In this chapter we consider some arguments that could be adopted for the primacy of the we, and examine their conceptual and empirical implications. We argue that the we needs to be seen as a developing and dynamic identity, not as something that exists fu
Certain strains of group A streptococci are known to bind IgA and/or IgG via a cell surface receptor, which may act as a virulence factor. The distribution of such receptors among routine clinical isolates was studied, using a total of 225 strains and an assay based on the binding of radiolabelled immunoglobulins. Among 194 throat strains isolated during three different time periods in two differe
Deviances in early event-related potential (ERP) components reXecting auditory and phonological processing are well-documented in children at familial risk for dyslexia. However, little is known about brain responses which index processing in other linguistic domains such as lexicon, semantics and syntax in this group. The present study investigated eVects of lexical-semantic priming in 20- and 24
Historien kring autism och pedagogik, samt referenser.
Crises or emergencies have drawn attention to the need of good emergency management capability in affected organizations or regions. An ongoing subproject in a Swedish multidisciplinary research programme aims at identifying areas or processes that are potentially important to include in the work of developing and improving an organization’s resilience and emergency management capability. This pap
In the early seventies Paola Zancani Montuoro suggested that a large paved structure, which had recently been uncovered at the site of Sybaris/Thourioi in southern Italy, was the remains of an ancient neosoikos, or shipshed. This idea quickly gained widespread acceptance and is still often repeated, despite some objections having been raised. In this paper it is argued that the structure, which ca
The aim of this study was to investigate the effect of absent CD40-CD40 ligand interactions in patients with X-linked hyper-IgM syndrome (XHIGM) on the generation of Th1 and Th2 immunity. Whole blood from patients and sex- and age-matched controls was stimulated with phorbol myristate acetate (PMA) and calcium ionophore A23187 in the presence of Brefeldin A. After 5 h, cellular production of inter
