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Background: There has been a global increase in the number of people who are dying of old age. This development implies a need for good palliative care among older persons at the end of life. Here nursing homes have an important role to play. However, the principles of palliative care have not been sufficiently applied in nursing homes, and there is a need to increase the implementation of palliat

This chapter focuses on the diplomatic, security, and defence dimensions of EU foreign policy. Developments in the last decade, not least Russia's annexation of Crimea, China's increasing global political - and not only economic - prevalence, and America's reoriented foreign policy all speak to this dynamic - and also render the EU a more challenging position in international relations. Recognitio

This chapter reviews the most important beginning with the long tradition of prescriptive tracts, offering observations and advice concerning the conduct of diplomacy. Authors from du Rosier to Nicolson were practitioners, who not only aimed at describing and explaining diplomacy but also had a clear prescriptive bent, offering recommendations as to the best conduct of diplomacy. War and military

This study addresses a one-to-one relation between articulation and acoustics at segment boundaries. The study focuses on Swedish word accents and how a rising or falling tone affect vowel segment duration. The paper explains how segment boundaries are a result of rapid movements of the articulators. In the acceleration profile, this is identified as peak acceleration, which can be measured. The t

Recent years has seen an unprecedented growth in emerging technologies like Additive manufacturing (AM), augmenting the manufacturing capabilities through a multitude of opportunities while also introducing unique constraints, such as support structures, and post-processing requirements. Taking full advantage of the potential of AM demands product designs to be optimised for both opportunities and

This article suggests a model for lexical verb semantics that unifies Halliday’s model for transitivity with Langacker’s concept of base and profile and also with a model for situation type (cf. Smith 1997). It is claimed that verbs adhere to one of four macro domains: the material, the social, the mental or the relational domain. Within these domains there are numerous types of verbs, such as mot

Trust is an important aspect of learning. However, there is little published research on how students perceive its value. In this article, we report on engineering students’ perceptions of the role of trust in their learning and their experiences of what teachers do in their courses that builds trust. Nine students participated in semi-structured interviews and 477 student replies to a survey sent

BakgrundFör att tackla den rådande SARS-COV-2-pandemin har det ställts höga krav på en snabb utveckling och utvärdering av nya antivirala läkemedel. Bland några av de antivirala läkemedelskandidaterna finns imiquimod, en TLR7 agonist normalt administrerad för behandling av könsvårtor och basalcellscarcinom. Eftersom det har påvisats att imiquimod kan öka den antivirala responsen, är vår hypotes at

In the 1930s and 1940s, Ukraine experienced political violence on an unprecedented scale. Political violence by the Soviet government and the German occupation authorities resulted in the death of millions, through starvation, deportations, and massacres, and left wounds which still have not fully healed. Independently of the Soviets and Nazis, mass political violence was carried out also by the O

Long life requires individuals to defend themselves against pathogens over prolonged periods of time whilst minimising damage to themselves. In vertebrates, pathogen defence is provided by two integrated systems, innate and adaptive immunity. Innate immunity is relatively nonspecific, resulting in collateral damage to hosts, and does not involve canonical immunological memory. In contrast, adaptiv

Ligand selectivity among the highly conserved galectins has been an ever-challenging objective. For galectin-8, a protein prevalent in both pathology and tissue distribution, we report phthalazinone-galactals that show excellent selectivity for the galectin-8N-terminal domain. A dissection of structure–activity relationships of the phthalazinone and an extensive molecular dynamics meta-analysis ac

Despite decades of research on the pathophysiology of depression, the development of new therapeutic interventions has been slow, and no biomarkers of treatment response have been clinically implemented. Several lines of evidence suggest that the clinical and biological heterogeneity among patients with major depressive disorder (MDD) has hampered progress in this field. MDD with low-grade inflamm

Background: Young adults with autism often have problems with body awareness, also acknowledged by physiotherapists. This may interfere with various physiological and psychological responses, expressed in reduced movement quality. Basic Body Awareness Therapy (BBAT) may be suitable to address these difficulties, to enhance body awareness and movement quality to manage everyday life. Body Awareness

This chapter presents a simulation model for the optimization of a reservoir system that is being developed. Simulation studies were carried out, firstly to determine the best (and by how much) irrigation facilities to provide in the proposed new scheme, and secondly, to see the applicability of simulation in reservoir planning. A computer simulation model using MATLAB has been developed to analyz

Haemoproteus blood parasites of birds are thought to be relatively benign. Recent findings show that infections may develop in the brain of birds, possibly distorting their orientation sense. Misdirected migration may lead migrants outside their range where they are recognized as vagrants and can transmit parasites to novel hosts.