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Pneumococcal surface protein C (PspC) is a major virulence factor of Streptococcus pneumoniae and interferes with complement activity by binding complement factor H (fH). In this study, protection against experimental sepsis caused by pneumococci carrying different PspC variants was evaluated by immunisation with the fH-binding fragment of PspC. The mechanisms of protection mediated by antibodies
Poor water quality and lack of access to improved water services continue to be problems in developing countries such as Peru, with a stronger vulnerability in rural communities. Aiming to enhance practical knowledge through a case study in the rural community of Cuncani, this thesis explores why this community has not been able to obtain a sustainable and safe water supply and how a water solutio
A robot should follow a given path as accurately as possible. There are however almost always deviations from the desired path, and when the deviations become too large it may be a problem. Some of the deviations stem from transmissions of the robot, and the deviations become more pronounced when there are process forces and gravitational forces present, that affect the transmissions. When positio
Title: The Carbon Impact of Component Production in China: Investigating the Impact of Carbon Border Adjustment Policies for a Global Manufacturing Company Authors: Fabian Bergman & Spiros Pavlidis Supervisor: Eva Berg, Lecturer at Engineering Logistics, Faculty of Engineering (LTH) at Lund University Examiner: Louise Bildsten, Associate Lecturer at Engineering Logistics, Faculty of Enginee
Den nuvarande ökningen av icke-statliga aktörer som bedriver kommersiell verksamhet i rymden har lett till juridiska frågor om bland annat ansvar. Är det nuvarande internationella rättsliga ramverket för yttre rymden tillräckligt etablerat för att hantera övergången från ett rättsområde som en gång dominerades av stater, till ett område som idag drivs av privata ekonomiska intressen? I denna uppThe important rise of non-state actors performing commercial activities in outer space has resulted in legal issues regarding inter alia responsibility. The question is whether the current international legal framework on outer space is sufficiently established to cope with a continuously shifting legal area once dominated by States to one today driven by private economic interests. This essay i
This thesis explores the underlying reasons for recent protests in Peru that began after the ousting of President Pedro Castillo in December of last year. The research is an explorative case study based on the thematic analysis of news articles. By drawing on decolonial theory, social movement theorising, as well as the concepts of identity and place, it examines the context of the protests and th
Sweden’s grocery distribution is routed through a limited number of upstream hubs and relies on corridors and ferry links. When disruptions affect a hub or a critical link, reallocations propagate fast and travel times increase, with some areas losing coverage temporarily. Decentralising the whole system is costly, so targeted resilience options must be evaluated. The purpose of this thesis is to
A key aspect of imperialism, colonialism, and capitalism is frontier-making. Frontiers are essential for ambitions of appropriation and extraction. This paper explores the discursive practices of frontier-making in Scandinavia including the conceptualization of parts of this region as empty space and ripe for exploitation, as wild, unruly and in need of domestication. These regions have historical
Stable carbon isotope curves derived from Lower Triassic carbonate rocks from three Iranian sections are established to investigate changes in the carbon cycle during the Early Triassic in this area. The sections are located in the south-center (Abadeh), north (Amol), and northwest (Zal) of Iran. All three curves show a similar pattern starting out with high δ13C values in the uppermost Permian de
This Letter presents a search for highly ionizing magnetic monopoles in (Formula presented) of ultraperipheral (Formula presented) collision data at (Formula presented) collected by the ATLAS detector at the LHC. A new methodology that exploits the properties of clusters of hits reconstructed in the innermost silicon detector layers is introduced to study highly ionizing particles in heavy-ion dat
Numerical models of meteorite delivery from impacts on the Moon have demonstrated that the impact event forming the lunar crater Tycho (~85 km diameter; ca. 109 Ma age) would have delivered considerable amounts of ejected material to Earth. The ejecta, containing lunar Ti- and V-rich chrome spinels, would have been distributed globally and admixed with seafloor sediments over a few meters of a typ
The current novel study aims was to development and characterization of gum based (guar gum: almond gum) composite formulations with or without addition of oregano essential oils to extend the shelf life of okra at ambient condition. In this study, the optimized composite of guar gum: almond gum (75:25 V/V) prepared with addition of different concentrations (0.05, 0.1 and 0.15 % (V/V) of oregano e
A search for leptoquarks decaying into the bτ final state is performed using Run 2 proton-proton collision data from the Large Hadron Collider, corresponding to an integrated luminosity of 139 fb −1 at s = 13 TeV recorded by the ATLAS detector. The benchmark models considered in this search are vector leptoquarks with electric charge of 2/3e and scalar leptoquarks with an electric charge of 4/3e.
(1) Background: The Berlin questionnaire (BQ) is a widely used survey to predict obstructive sleep apnea (OSA). Considering the confounding effect of obesity and hypertension on the clinical course of COVID-19, we have recently developed a modified BQ (mBQ) based on the subscales snoring intensity/frequency, witnessed apneas and morning/daytime tiredness, and demonstrated that patients with high-r
A search for a WZ resonance, in the fully leptonic final state (electrons or muons), is performed using 139 fb - 1 of data collected at a centre-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. The results are interpreted in terms of a singly charged Higgs boson of the Georgi–Machacek model, produced by WZ fusion, and of a Heavy Vector Triplet, with the resonance produc
The major form of complement component C4b-binding protein, a regulator of the complement system, is composed of seven identical 70-kDa alpha chains, each containing a binding site for the complement protein C4b. We recently showed that C4b-binding protein also contains a unique 45-kDa beta chain. It is disulfide-linked to the central core and contains a binding site for the vitamin K-dependent pr
OBJECTIVES: The Swedish surveillance system aiming to reveal undetected Hand-Arm Vibration Syndrome (HAVS) in workers exposed for vibrations is regulated by the provision AFS 2019:3. The goal for the surveillance system is to diagnose HAVS, as well as to find workers at risk for developing HAVS due to other conditions. The national guidelines stipulate examination using at least two out of four ha
