Filtyp
This paper is devoted to a discussion of Catford's and Fischer-Jørgensen's defence of the classical vowel articulation model (1, 2, 3). Objections to the model are not directed at Bell's personality, but at the theoretical structure of his model: critical functions of the model are contradicted by empirical data and by acoustical theory. Nor are the ojections only relevant for amendments introduce
The present thesis investigates the usage of cultural heritage resources on the web. In recent years cultural heritage objects has been digitalized and made available on the web for the general public to use. The thesis addresses to what extent the digitalized material is used, and how findable it is on the web. On the web resources needs to be findable in order to be visited and used. The study i
The ATLAS experiment is one of the four experiments at the Large Hadron Collider (LHC), which is supposed to be operational in early 2007. Proton-proton collisions at an unprecedented center-of-mass energy of 14 TeV will probe new frontiers of the universe, hopefully providing a better understanding of the laws governing our universe. Although the ATLAS detector has been optimized to search for th
This paper examines mass media coverage of Taiwanese high-level political visits to Japan and critically analyzes the phenomenon of nostalgic repetition as a narrative formula in such sources. Stressing its elements of pathos, nostalgia, and sentimental reassurance, I argue that the repetition formula presents an avenue of immense strategic advantage for visiting pro-independence politicians vis-à
A total synthesis of transtaganolide E and F, proposed intermediates in the biosynthesis of the potent transtaganolides, including an Ireland-Claisen rearrangement and a high-pressure intramolecular Diels-Alder cycloaddition reaction of an unactivated 2-pyrone derivative, is reported. The implication of the results to the proposed transtaganolides biosynthesis is discussed.
BACKGROUND Linomide, Figure 1, produces robust and consistent in vivo growth inhibition of prostate cancer models via its anti-angiogenic activity and inhibition of autoimmune encephalomyelitis models of multiple sclerosis (MS). MS clinical trials were discontinued because of unacceptable toxicity, due to dose-dependent induction of proinflammation. METHODS Therefore, linomide analogs were initia
We present a rate equation model for the TGF-beta pathway in endothelial cells together with novel measurements. This pathway plays a prominent role in inter- and intracellular communication and subversion can lead to cancer, fibrosis vascular disorders, and immune diseases. The model successfully describes the kinetics of experimental data and also correctly predicts the behavior in experiments w
The CBP gene at 16p13 fuses to MOZ and MLL as a result of the t(8;16)(p11;p13) in acute (myelo)monocytic leukemias (AML M4/M5) and the t(11;16)(q23;p13) in treatment-related AML, respectively. We show here that a novel t(10;16)(q22;p13) in a childhood AML M5a leads to a MORF-CBP chimera. RT-PCR using MORF forward and CBP reverse primers amplified a MORF-CBP fusion in which nucleotide 3103 of MORF
Previous research has been inconclusive as regards the effect of outward foreign direct investment (FDI) on domestic investments. In this article, we show that this inconclusiveness can be explained at a disaggregated level as a function of the way industries are organized. Based on a simple theoretical framework including monitoring and trade costs, we argue that a complementary relationship can
The evolutionary history of the common chloroplast (cp) genome of the allotetraploid Arabidopsis suecica and its maternal parent A. thaliana was investigated by sequencing 50 fragments of cpDNA, resulting in 98 polymorphic sites. The variation in the A. suecica sample was small, in contrast to that of the A. thaliana sample. The time to the most recent common ancestor (T-MRCA) of the A. suecica cp
