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State-copying and Recomputation in Parallel Constraint Programming with Global Constraints

In this paper we discuss parallelization and distribution of problems modeled in a constraint programming (CP) framework. We focus on parallelization of depth-first search methods, since search is the most time-consuming task in CP. The current hardware development is moving towards multi-core processors and the cost of building distributed systems is shrinking. Hence, parallelization and distribu

Carsim: A System to Visualize Written Road Accident Reports as Animated 3D Scenes

This paper describes a system to create animated 3D scenes of car accidents from reports written in Swedish. The system has been developed using news reports of varying size and complexity. The text-to-scene conversion process consists of two stages. An information extraction module creates a structured representation of the accident and a visual simulator generates and animates the scene. We firs

Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development.

Although bone marrow (BM) represents the main site for postnatal NK cell development, recently a distinct thymic-dependent NK cell pathway was identified. These studies were designed to investigate the role of cytokines in regulation of thymic NK cells and to compare with established regulatory pathways of BM-dependent NK cell compartment. The common cytokine receptor gamma-chain (Il2rg) essential

Electrochemical Investigation of Nickel Pattern Electrodes in H-2/H2O and CO/CO2 Atmospheres

In this study, nickel pattern electrodes were electrochemically investigated in a three-electrode setup, operating both with H-2/H2O and CO/CO2 atmospheres. Heating introduced structural differences in the nickel layer among the pattern electrodes, which appear to affect the electrode performance. Both dense and porous nickel pattern electrodes were formed by heating. Holes appeared in the nickel

Late Ordovician-Early Silurian delta C-13 chemostratigraphy in the Upper Mississippi Valley: implications for chronostratigraphy and depositional interpretations

A pioneer study of the previously unknown delta C-13 chemostratigraphy in the Ordovician/Silurian boundary interval in eastern Iowa and northeastern Illinois resulted in the discovery of the Hirnantian Isotope Carbon Excursion (HICE). The presence of this major isotope excursion in the Mosalem Formation in Iowa and the Wilhelmi Formation in Illinois, which indicates that the excursion interval in

Mortality results from the Goteborg randomised population-based prostate-cancer screening trial

Background Prostate cancer is one of the leading causes of death from malignant disease among men in the developed world. One strategy to decrease the risk of death from this disease is screening with prostate-specific antigen (PSA); however, the extent of benefit and harm with such screening is under continuous debate. Methods In December, 1994, 20 000 men born between 1930 and 1944, randomly sam

Membrane protein identification: N-terminal labeling of nontryptic membrane protein peptides facilitates database searching

Membrane proteins are fairly refractory to digestion especially by trypsin, and less specific proteases, such as elastase and pepsin, are much more effective. However, database searching using nontryptic peptides is much less effective because of the lack of charge localization at the N and C termini and the absence of sequence specificity. We describe a method for N-terminal-specific labeling of

Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men - The MrOS study in Sweden

Objectives This study sought to determine whether serum levels of testosterone and estradiol associate with lower extremity peripheral arterial disease (PAD) in a large population-based cohort of elderly men. Background Few studies have explored the relationship between serum sex steroids and lower extremity PAD in men. Methods The Swedish arm of the MrOS (Osteoporotic Fractures in Men) study (n =

Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas

P>Toll-like receptors (TLRs) are increasingly implicated in the pathogenesis of cancer. The present study describes TLR expression and function in healthy and malignant airway epithelial cells. The squamous cell carcinoma cell line Detroit-562 was compared with the healthy bronchial epithelial cell line NL-20 and primary human nasal epithelial cells (HNECs). TLR2, TLR3 and TLR5 were present in pri

Critical Role of P-Selectin and Lymphocyte Function Antigen-1 in Radiation-Induced Leukocyte-Endothelial Cell Interactions in the Colon.

Purpose Radiation therapy is frequently used in treating different types of tumors, although associated with serious side effects, such as fibrosis and complicated diarrhea. This study was designed to define the adhesive mechanisms behind radiotherapy-induced leukocyte recruitment in the colon. Methods All mice, except control animals, were radiated with a single dose of 20 Gy. Mice were pretreate

Retinoic acid receptor signaling levels and antigen dose regulate gut homing receptor expression on CD8(+) T cells

Recent studies have highlighted a central role for intestinal dendritic cells (DCs) and vitamin A metabolite retinoic acid (RA) in the generation of alpha 4 beta 7(+) CCR9(+) "gut tropic" effector T cells. Here, using RA-responsive element reporter mice, we demonstrate that both splenic and mesenteric lymph node (MLN) DCs enhanced retinoic acid receptor (RAR) signaling in CD8(+) T cells; however,

A digitally controlled PLL for digital SOCs

A fully integrated digitally controlled PLL used as a clock multiplying circuit is designed and fabricated. The PLL has no off-chip components and it is made from standard cells found in most digital standard cell libraries. It is therefore portable between processes as an IP-block. Using a 0.35 μm standard CMOS process and a 3.0 V supply, the PLL has a frequency range of 152 MHz to 366 MHz and oc

Lyme borreliosis reinfection: might it be explained by a gender difference in immune response?

Lyme borreliosis is a tick-borne disease often manifesting as a circular skin lesion. This cutaneous form of the disease is known as erythema migrans. In a 5-year follow-up study in southern Sweden, 31 of 708 individuals initially diagnosed with erythema migrans and treated with antibiotics were found to be reinfected with Borrelia burgdorferi. Although men and women were tick-bitten to the same e

Predicted properties of eclipsing binaries observable by Gaia

Using a population synthesis model we estimate the fraction of stars of different types that are likely to show eclipses, as a function of the period. The population model is based on the bse-code from Hurley et al. (2002) which is a rapid binary evolution code that include all common effects in close binaries such as mass transfer, tidal locking, wind etc. We use this to evolve millions of system