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Popular Abstract in Swedish Ärfltiga faktorer orsakar ledgångsreumatism Reumatoid artrit (RA) även kallat ledgångsreumatism är en ledsjukdom som drabbar 1% av befolkningen, framförallt kvinnor. Orsaken till sjukdommen är inte känd, men man tror att det finns en ärftlig faktor som avgör om en viss individ kan utveckla reumatoid artrit eller inte. Den genetiskassociationen man idag vet om är till mThe immune pathology and MHC association of chronic arthritis was studied in three rat models for reumatoid arthritis (RA). Susceptible rat strains develop a T cell dependent chronic disease after immunization with rat collagen type II (CII). The LEW rat does not develop arthritis after immunization with rat CII, but a heterologous immune response to pepsin can break the tolerance to CII and rende

The measured water vapour resistances of clothing ensembles differ among laboratories particularly for impermeable clothing. Due to the moisture transfer in the clothing ensemble, evaporative heat losses in initial, transient and steady state phases are different. The purpose of this study was to investigate moisture absorption inside underwear and outer layer as a function of time, to quantify th

The purpose of this research is to examine the implications of the provisions in the Swedish Code of Corporate Governance (the Code) concerning auditor attestation of the internal control report. We will focus on how the auditors’ augmented responsibilities will affect the efficiency in the audit process.Our research indicates that the main benefit from reviewing the internal control report is ach

Syftet med vår studie är att undersöka de problem som kan uppstå vid en överföring av ett styrinstrument, innehållande Key Performance Indicators, från en organisation till en annan i samband med förvärv. Uppsatsen utgår från en fallstudie av ett företag i kemibranschen. I vår fallstudie använder vi ett abduktivt angreppssätt och en kvalitativ metod. I den teoretiska referensramen utgår vi ifrån t

The results of a theoretical study of the ground state, 1(1)A(g), and of the lowest B-1(u) states of trans-stilbene are presented. The vertical and adiabatic excitation energies of the lowest B-1(u) states have been computed using multiconfigurational SCF theory, followed by second-order perturbation. theory. It is shown that the two lowest excited states are separated by a small energy gap in the

Invariant NKT cells (iNKT cells) are characterized by a semi-invariant TCR comprising an invariant a-chain paired with beta-chains with limited BV gene usage which are specific for complexes of CD1d and glycolipid Ags like a-galactosylceramide (a-GalCer). iNKT cells can be visualized with a-GalCer-loaded CD1d tetramers, and the binding of mouse CD1d tetramers to mouse as well as to human iNKT cell

Secretagogin is a newly identified calcium-binding protein selectively expressed in neuroendocrine tissue and pancreatic beta-cells. The function of secretagogin is unknown, but it has been suggested in beta-cells to influence calcium-influx, insulin secretion and proliferation, and has been observed downregulated in diabetes-prone BB rat islets exposed to cytokines. In the present study, we ident

Although interactions in biological systems occur in the presence of a large number of charged species, the binding of charged ligands to different biomolecules is often analyzed in a simplified model focusing only upon the receptor, ligand, and added salt. Here we demonstrate that the presence of charged macromolecules can affect binding to the receptor in an unexpected way. Experimental studies

A fluorescence lidar measurement has been performed on the castle Övedskloster in Sweden. A mobile system from the Lund University was placed at ~40 m distance from the sandstone façade. The lidar system, which uses a frequency-tripled Nd:YAG laser with a 355-nm pulsed beam, induces fluorescence in each target point. Areas were studied by using whisk-broom scans. The possibility of detecting biode

The normal approach to digital control is to sample periodically in time. Using an analog of integration theory we can call this Riemann sampling. Lebesgue sampling or event based sampling is an alternative to Riemann sampling. It means that signals are sampled only when measurements pass certain limits. In this paper it is shown that Lebesgue sampling gives better performance for some simple syst

We report on studies of the formamidinium lead triiodide (FAPbI3) perovskite film using time-resolved terahertz (THz) spectroscopy (TRTS) and flash photolysis to explore charge carriers generation, migration, and recombination. The TRTS results show that upon femtosecond excitation above the absorption edge, the initial high photoconductivity (∼75 cm(2) V(-1) s(-1)) remains constant at least up to

We have recently reported Monte Carlo simulations for a system of two infinite like-charged plates in a dipolar fluid solvent (Pegado et al 2008 J. Chem. Phys. at press). The pressure as a function of plate separation qualitatively reproduces the ion-ion correlation attraction picture seen in primitive model studies, where the solvent only enters the picture implicitly through its dielectric const

The G-protein coupled receptor associated protein β-arrestin-1 is crucial for the regulation of numerous biological processes involved in cancer progression, such as intracellular signaling and cell motility. The encoding gene ARRB1 is harbored in the same chromosomal region as the CCND1 gene (11q13). Amplification of CCND1, frequently encountered in breast cancer, often involves coamplification o

Two basic routes for planetesimal formation have been proposed over the last decades. One is a classical 'slow-growth' scenario. Another one is particle concentration models, in which small pebbles are concentrated locally and then collapse gravitationally to form planetesimals. Both types of models make certain predictions for the size spectrum and internal structure of newly born planetesimals.

This paper studies the importance of the interdependences within platform-based markets. Specifically, the work examines the influence of complementary product portfolios on the adoption of platforms by individuals. The study analyzes data from a panel of 17 video game platforms in three regions (the US, Japan and Europe) for the period between 1989 and 2011. The results suggest that platform adop

BACKGROUND: The dual mobility acetabular cup (DMC) was designed to reduce prosthetic instability and has gained popularity for both primary and revision total hip arthroplasty (THA). We compared the risk of revision of primary THA for primary osteoarthritis between patients treated with a DMC and those who received a metal-on-polyethylene (MoP) or ceramic-on-polyethylene (CoP) bearing. METHODS: A

Dynamic glucose-enhanced (DGE) imaging uses chemical exchange saturation transfer magnetic resonance imaging to retrieve information about the microcirculation using infusion of a natural sugar (D-glucose). However, this new approach is not yet well understood with respect to the dynamic tissue response. DGE time curves for arteries, normal brain tissue, and cerebrospinal fluid (CSF) were analyzed

In the aggregate industry the use of geophysical measuring is rare. The aim of this project is to investigate how geophysical instruments can be a tool in prospecting for rock quarries, and also how they can be a help in which direction they should expand in. To have control over the quality of the aggregates is important and therefore to know when the rock mass is changing is of interest for the