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Identification and validation of NFIA as a novel prognostic marker in renal cell carcinoma

Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). Although tumour stage and grade can provide important information, they fail to consider patient- and tumour-specific biology. In this study, we set out to find a novel molecular marker of RCC by using hepatocyte nuclear factor 4A (HNF4A), a transcription factor implicated in RCC pro

A pilot study of methods for prediction of poor outcome by head computed tomography after cardiac arrest

Introduction: In Sweden, head computed tomography (CT) is commonly used for prediction of neurological outcome after cardiac arrest, as recommended by guidelines. We compare the prognostic ability and interrater variability of routine and novel CT methods for prediction of poor outcome. Methods: Retrospective study including patients from Swedish sites within the Target Temperature Management afte

The effect of metamorphism on the aggregate properties of gabbroic rocks

Granitic rocks are durable materials sought after for the production of road and railroad aggregates. Granitic bedrock commonly, however, includes gabbroic components, which may enhance or decrease the aggregate performance. This study evaluates the variation in resistance to fragmentation (Los Angeles value, LA) and wear/abrasion (micro-Deval value, MDE) for the fraction 10/14 mm of gabbro in dif

Measuring Up to the Humanities : Navigating the Epistemological Advantage of Classical Humanism in Nineteenth-Century Scholarly Periodicals

This chapter analyzes the epistemological hierarchy around the middleof the nineteenth century in Sweden through efforts to mobilize supportfor natural science in scholarly periodicals. It is argued that scholarlycommunication was key to achieving legitimacy for natural science, butthat such efforts were mitigated by a dominant view of the humanitiesin general and classical humanism in particular

Extremal states and coupling properties in electroelasticity

Electroelastic materials possess properties most attractive for the design of smart devices and systems such as actuators and sensors. Typical polymers show changes in shape under the action of an electric field, and vice versa, together with fast actuation times, high strain levels and low elastic moduli. This paper deals with an Ogden model inspired framework for large deformation electroelastic

Host Immunity-Microbiota-Virus Interactions at the Intestinal Mucosal surface in Health and Disease

The presence of viral immune triggers at the intestinal mucosa can have multipleglobal effects on intestinal integrity, including relative protection fromsubsequent inflammatory bowel disease. During the last century, the westernworld has achieved a remarkable success in preventing infectious diseases,which increased the general life expectancy dramatically. However, theincidence and prevalence of

A resilience approach to DMO communication during the COVID-19 pandemic.

This article addresses how urban Destination Management Organisations (DMOs) in Sweden, have understood their communicative role, developed communicative strategies and tactics in relation to stakeholders during the COVID-19 pandemic. The aim of this research is to explore communication strategies for urban destination resilience. DMOs have a key role in balancing the interest of stakeholders, the

Test Scheduling for 3D Stacked ICs under Power Constraints

This paper addresses Test Application Time (TAT) reduction for core-based 3D Stacked ICs (SICs). Applying traditional test scheduling methods used for non-stacked chip testing where the same test schedule is applied both at wafer test and at final test to SICs, leads to unnecessarily high TAT. This is because the final test of 3D-SICs includes the testing of all the stacked chips. A key challenge

The comparative relationships between locations of the papillary muscles and electrophysiologic QRS axis in patients with atrioventricular septal defect and common as opposed to separate orifices in the valve guarding the common atrioventricular junction

Background: Knowledge regarding factors that influence deviation of the QRS axis is important when seeking to differentiate between physiological and pathological changes. We hypothesised that, in contrast to those patients with an atrioventricular septal defect and common atrioventricular junction permitting only atrial shunting, those associated with ventricular shunting would show no relationsh

Amorphous silica transport in the Ganges basin: Implications for Si delivery to the oceans

Rivers transport similar to 6 x 10(12) mol yr(-1) of dissolved Si (DSi) from the continents to the oceans. They also carry amorphous silica (ASi), solid phases likely to dissolve in seawater. Unfortunately, the magnitude of this flux is poorly constrained at a global scale. We present 92 new ASi values from suspended particulate matter (SPM) from the Ganges basin. Bulk SPM is 1.2% ASi, and mean AS

Hijacking Banksy : a discussion about ethical research practice within the street art world

Taking as its point of departure an article entitled "Tagging Banksy: using geographic profiling to investigate a modern art mystery" which was published in Journal of Spatial Science in March 2016, the present keynote paper aims to open up a discussion about ethical research practice within the street art world and the implications for street art researchers when such practice is violated.

Learning to draw with the HIPP application

In this paper, we describe an audio-haptic drawing application prototype that has recently been tested by five pupils who are 8-13 years. The application has been used by pupils, assistants and teachers to access graphics and create graphics that are accessible for pupils with severe visual impairment or blindness. We have observed a spread in the actual use of the system that seems to depend, for