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Improving Predictive Models of In-Stream Phosphorus Concentration Based on Nationally-Available Spatial Data Coverages

Spatial data are playing an increasingly important role in watershed science and management. Large investments have been made by government agencies to provide nationally-available spatial databases; however, their relevance and suitability for local watershed applications is largely unscrutinized. We investigated how goodness of fit and predictive accuracy of total phosphorus (TP) concentration m

An official American Thoracic Society workshop report : Stem cells and cell therapies in lung biology and diseases

The University of Vermont College of Medicine and the Vermont Lung Center, in collaboration with the NHLBI, Alpha-1 Foundation, American Thoracic Society, European Respiratory Society, International Society for Cell Therapy, and the Pulmonary Fibrosis Foundation, convened a workshop, "Stem Cells and Cell Therapies in Lung Biology and Lung Diseases, " held July 29 to August 1, 2013 at the Universit

Quantitative assessment of the impact of climate change on creep of concrete structures

Creep of concrete structures is in most cases regarded as a serviceability problem that may have impacts on maintenance and repair costs but cannot lead to structural collapse. However, several structural collapses during the past decades have been, at least partly, attributed to excessive creep deformations. Recent studies suggest that concrete creep may be further exacerbated by climate change.

Blended and Online Learning Environments : Motivations, Contradictions, and Influencing Factors

Blended and online learning environments continue to grow, transforming higher education. The motivation behind this study is to explore blended and online learning environments, from the perspective of students, through the lens of Activity Theory (AT). Based on 12 virtual semi-structured interviews with Master's (MSc) students at one University in England, the paper sheds light onto some of the

Effects of temperature in the estimation of inhomogeneous magnetic transfer (ihMT) in post-mortem human brain

Inhomogeneous magnetic transfer (ihMT) is more sensitive to myelin macromolecules than standard MT proxies. Measuring ihMT in the multi-parameter mapping protocol allows calculating ihMT from MT saturation (MTsat) maps and thus inherently correct for the undesired dependencies on flip angle and the longitudinal relaxation rate. Further validation of this new ihMT metric requires measurement of MPM

Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk

Diabetes is a complex and multifactorial disease that affects millions of people worldwide, reducing the quality of life significantly, and results in grave consequences for our health care system. In type 2 diabetes (T2D), the lack of β-cell compensatory mechanisms overcoming peripherally developed insulin resistance is a paramount factor leading to disturbed blood glucose levels and lipid metabo

Osteopontin and malaria : no direct effect on parasite growth, but correlation with P. falciparum-specific B cells and BAFF in a malaria endemic area

Background: The dysregulation of B cell activation is prevalent during naturally acquired immunity against malaria. Osteopontin (OPN), a protein produced by various cells including B cells, is a phosphorylated glycoprotein that participates in immune regulation and has been suggested to be involved in the immune response against malaria. Here we studied the longitudinal concentrations of OPN in in

Bedazzled by technology

This paper is about the socio-technical findings of a project that was carried out for an organisation in the educational sector. The main aim of the project was to explore the possibilities of developing a mobile Augmented Reality authoring tool that educators would use to create AR experiences in attempt to improve their teaching methods. A novel ‘solution’ was designed and prototyped, which ini

Systemic sustainability analysis in small and medium-sized enterprises (Smes)

Sustainability is rarely implemented in employee work practices in small and medium-sized enterprises (SMEs). The authors note that SMEs should implement sustainability practices as integrated part of work activities to ensure long term success. This paper describes an empirical study of SMEs sustainability on employee real work practices. A relevant perspective is offered by the triple bottom lin

On the construction of authentication codes with secrecy and codes withstanding spoofing attacks of order L ≥ 2

We present an analysis of some known cartesian authentication codes and their modification into authentication codes with secrecy, with transmission rate R = r/n, where n = 2, 3, …, and 1 ≤ r ≤ n - 1 using (n - r)(r + 1) q-ary key digits. For this purpose we use a grouping technique. Essentially the same key grouping technique is used for the construction of codes that withstand spoofing attacks o

IL-15 Upregulates Telomerase Expression and Potently Increases Proliferative Capacity of NK, NKT-Like, and CD8 T Cells

Interleukin-15 (IL-15) is a cytokine that has been shown to expand CD8 T cell and natural killer (NK) cell populations, and therefore has potential for potentiating adoptive immune cell therapy for cancer. Previously, IL-15 has been shown to induce proliferation of CD8 memory T cells through activation of telomerase. Here, we investigated whether telomerase is also activated during the IL-15 media

Bone Marrow Neutrophils of Multiple Myeloma Patients Exhibit Myeloid-Derived Suppressor Cell Activity

Activated normal density granulocytes (NDGs) can suppress T-cell responses in a similar way as myeloid-derived suppressor cells (MDSCs). In this study, we tested the hypothesis that NDGs from blood and bone marrow of multiple myeloma (MM) patients have the ability to suppress T-cells, as MDSC. MM is an incurable plasma cell malignancy of the bone marrow. Like most malignancies, myeloma cells alter

Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months : follow-up of a longitudinal clinical study

Chronic breathlessness is a dominating symptom that restricts daily life for many people with cardiorespiratory disease [1]. Different dimensions of the symptom, such as the intensity, sensory qualities and emotional responses, can be assessed using the instruments Dyspnea-12 (D-12) [2] and the Multidimensional Dyspnea Profile (MDP) [3], which share similarities in the underlying constructs of wha

Clinical characterization and identification of rare genetic variants in atypical hemolytic uremic syndrome : a Swedish retrospective observational study

INTRODUCTION: Complement-mediated atypical hemolytic uremic syndrome (aHUS) is an ultra-rare renal disease primarily caused by genetic alterations in complement proteins. The genetic work-up required for confirmation of diagnosis is complicated and not always logistically accessible. The aim of the present study was to apply a diagnostic scheme compliant with the ACMG guidelines to investigate the

En studie om sambandet mellan priselasticitet och konsumenters lojalitet för livsmedel i Sverige

Vår studie visade att det fanns ett samband mellan marknadsandel och lojalitet. Vidare vad gäller sambandet mellan lojalitet och priselasticitet samt pris och lojalitet hittades inget samband eftersom denna var väldigt svag.Our study showed that there is a relationship between market share and loyalty. Regarding the relationship between loyalty and price elasticity and price and loyalty, the study shows a very weak correlation. Thus the conclusion that there is no correlation .

Pop-up Stores: The Attraction of Ephemeral Experiences - A phenomenological study on consumers' experiences in pop-up stores

The purpose of this paper is to contribute with a new understanding of pop-up stores through a phenomenological perspective by examining how consumers experience pop-up stores. The study also aims to look at a micro and macro perspective to better understand how this phenomenon links to and is shaped by macro level trends of the contemporary consumer culture. Given the purpose and aim of the repor

Water use efficiency in agricultural irrigation in Egypt: A qualitative study on the complexities of utilising fossil groundwater resources in the face of water scarcity

This study examines the adaptive capacity of desert farming in Egypt to imminent water scarcity and discusses the sustainability of fossil groundwater extraction. Through qualitative semi-structured expert interviews, the study identifies clear research and data gaps related to the Nubian Sandstone Aquifer System (NSAS) and highlights the need for a nuanced approach to fossil groundwater extractio