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Blood biomarkers for the prediction of outcome after cardiac arrest : an international prospective observational study within the Targeted Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial

BACKGROUND: Prognostication of recovery in patients who are unconscious following cardiac arrest can be guided by concentrations of brain injury biomarkers in the blood. The optimal biomarker and cutoff concentrations for the prediction of outcome remain unknown. In this study, we aimed to evaluate which biomarker of brain injury is most accurate for predicting functional outcome after cardiac arr

The Case of Sillanpää : Translation, the Nobel Prize, and a Neighbor in Distress

This article explores the intricate relation between translation and the Nobel Prize in Literature through the lens of a special case: the 1939 award to Finnish novelist Frans Eemil Sillanpää. The discussions in the Nobel committee, and the decision of the Swedish Academy to select Sillanpää for the prize, were deeply affected by the long and complicated political and cultural history of neighbors

Multidisciplinary monitoring of an in-situ remediation test of chlorinated solvents

Pollutions on and within the underground poses risks for groundwater contamination and is a widespread global problem. Common remediation methods based on digging and removal can be expensive and have limitations, while in-situ remediation is an attractive alternative. However, there is a need to develop tools to monitor the effectiveness both in terms of the successful injection of remediation fl

VINTERGATAN-GM : How do mergers affect the satellite populations of MW-like galaxies?

We investigate the impact of a galaxy’s merger history on its system of satellites using the new VINTERGATAN-GM suite of zoom-in hydrodynamical simulations of Milky Way-mass systems. The suite simulates five realizations of the same halo with targeted ‘genetic modifications’ of a z ≈ 2 merger, but resulting in the same halo mass at z = 0. We find that differences in the satellite stellar mass func

Habitual Coffee, Tea, and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity

CONTEXT: Cardiometabolic multimorbidity (CM) is an increasing public health concern. Previous observational studies have suggested inverse associations between coffee, tea, and caffeine intake and risks of individual cardiometabolic diseases; however, their associations with CM and related biological markers are unknown.METHODS: This prospective study involved 172 315 (for caffeine analysis) and 1

Licence to Regulate: Article 114 TFEU as Choice of Legal Basis in the Digital Single Market

This chapter discusses Article 114 TFEU as the choice of legal basis in the Digital Single Market. It argues that the EU’s competence in the internal market has developed into a default option for harmonising measures in digitalisation, exacerbated by the Union’s new regulatory approach. With particular reference to the area of competition law and the recently introduced Digital Markets Act, Artic

DICHOTOMY RESULTS FOR EVENTUALLY ALWAYS HITTING TIME STATISTICS AND ALMOST SURE GROWTH OF EXTREMES

Suppose (f,X, μ) is a measure preserving dynamical system and φ: X → R a measurable function. Consider the maximum process Mn := max{X1, ,Xn}, where Xi = φ ○ fi-1 is a time series of observations on the system. Suppose that (un) is a non-decreasing sequence of real numbers, such that μ(X1 > un) → 0. For certain dynamical systems, we obtain a zero- one measure dichotomy for μ(Mn ≤ un i.o.) dependin

Economic Organizations and the Transformation Towards Degrowth

Degrowth seeks to achieve a sustainable society in the future. It implies overcoming capitalist norms and structures. Economic organizations have found little attention in degrowth scholarship. The existing literature focuses on degrowth compatibility without the wider structural and societal consideration that degrowth implies. Further, it is riddled with incoherences, such as a supposed compatib

A new mass and radius determination of the ultra-short period planet K2-106b and the fluffy planet K2-106c

Ultra-short period planets (USPs) have orbital periods of less than 1 d. Since their masses and radii can be determined to a higher precision than long-period planets, they are the preferred targets to determine the density of planets which constrains their composition. The K2-106 system is particularly interesting because it contains two planets of nearly identical masses. One is a high-density U

Sweden, Russia, and the 1617 Peace of Stolbovo

In 1617, after seven years of war between Sweden and Russia and talks facilitated by English and Dutch diplomats, the peace treaty of Stolbovo was signed. This important but little-studied document was to form the basis for relationships between Sweden and Russia for the next one hundred years, before it was replaced by the Peace of Nystad in 1721, and it had a huge influence on the lives of the p

Real-Time Minimum-Time Lane Change Using the Modified Hamiltonian Algorithm

A minimum-time lane change maneuver is executed under friction-limited conditions using (1) the Modified Hamiltonian Algorithm (MHA) suitable for real-time control and (2) numerical optimization for comparison. A key variable is the switching time of the acceleration reference in MHA. Considering that MHA is based on an approximate vehicle model to target real-time control, it cannot exactly match

Longer and heavier road freight vehicles in Sweden

PurposeLonger and heavier road freight vehicles, so called High Capacity Vehicles (HCVs) are likely to be implemented by the Swedish government in the near future. This paper analyses the effects on tonne-kilometres, vehicle-kilometres, CO2 and socio-economics of three possible implementation strategies (HCVs on all roads, a designated road network, a designated road network with km-based truck ch

MOCCA-SURVEY database I. Accreting white dwarf binary systems in globular clusters - IV. Cataclysmic variables - properties of bright and faint populations

We investigate here populations of cataclysmic variables (CVs) in a set of 288 globular cluster (GC) models evolved with the MOCCA code. This is by far the largest sample of GC models ever analysed with respect to CVs. Contrary to what has been argued for a long time, we found that dynamical destruction of primordial CV progenitors is much stronger in GCs than dynamical formation of CVs, and that

Heard But Not Seen—Swedish Opera Choristers’ Thoughts on Occupational Environment and Vocal Health, an Explorative Qualitative Study

Objective: Professional operatic singing is vocally demanding, making the maintenance of professional vocal health a paramount concern for the opera chorister. Occupational environment has been shown to affect vocal health for other vocally dependent professions. Hence, the objective of the current study was to explore what occupational environment factors affect the professional vocal health of S