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Glutamic acid decarboxylase 65 (GAD65) and autoantibodies specific for GAD65 (GADA) are associated with autoimmune diseases including Stiff Person Syndrome (SPS) and Type 1 diabetes (T1D). GADA is recognized as a biomarker of value for clinical diagnosis and prognostication in these diseases. Nonetheless, it remains medically interesting to develop sensitive and specific assays to detect GAD65 pre
Solar cells based on organometal halide perovskites have seen rapidly increasing efficiencies, now exceeding 15%. Despite this progress, there is still limited knowledge on the fundamental photophysics. Here we use microwave photoconductance and photoluminescence measurements to investigate the temperature dependence of the carrier generation, mobility, and recombination in (CH3NH3)PbI3. At temper
The concept of disaster risk reduction has gained more and more attention since the end of the 20th century due to the exponential increased loss of human lives and material losses, without any evidence of increased number of hazardous events. Instead of just managing disastrous events, a greater emphasis has been put on prevention efforts; an understanding of underlying drivers and vulnerabilitie
Trade costs and sunk export costs play a crucial role in defining trade flows between countries and, directly, affect firms’ strategic decisions in terms of international expansion. Trade costs include all the costs attached to a delivery of good to a final user and, thus, incorporate transportation costs, policy barriers, information costs, contract costs and currency costs. Sunk costs include co
The aim of this thesis is to analyze the extent to which policy integration and project coordination has been achieved and what the effects of these two factors have been in relation to the fisheries sector in the Lake Victoria region in the East African Community (EAC). Theories pertaining to benefits of policy integration and project coordination are utilized as well as the theory of the "T
The aim of this thesis is to give a clearer empirical picture of innovations and its connection to economic growth. As a point of departure we use an endogenous growth model, the Romer model, to theoretically develop this connection. This is shown through a modified equation for accumulation of technology. The model was extended with a modified variable for research productivity and a new variable
HLA DR4-DQ8 and DR3-DQ2 haplotypes account for 89% of newly diagnosed cases of type 1 diabetes (T1D) in Sweden. The presence of a single copy of DQ6 confers protection. The aim of the present study is to evaluate whether the risk conferred by high risk HLA DR and DQ to T1D is similar in all regions of Sweden and see whether there are any significant regional differences. The subjects comprised 799
Autoimmune diabetes is a consequence of immune-cell infiltration and destruction of pancreatic β-cells in the islets of Langerhans. We analyzed the cellular composition of the insulitic lesions in the autoimmune-prone non-obese diabetic (NOD) mouse and observed a peak in recruitment of plasmacytoid dendritic cells (pDCs) to NOD islets around 8-9 weeks of age. This peak coincides with increased spo
Streptococcus pneumoniae (the pneumococcus) is a common colonizer of the human nasopharynx. Despite a low rate of invasive disease, the high prevalence of colonization results in millions of infections and over one million deaths per year, mostly in individuals under the age of 5 and the elderly. Colonizing pneumococci form well-organized biofilm communities in the nasopharyngeal environment, but
The active phase of Pd during methane oxidation is a long-standing puzzle, which, if solved, could provide routes for design of improved catalysts. Here, density functional theory and in situ surface X-ray diffraction are used to identify and characterize atomic sites yielding high methane conversion. Calculations are performed for methane dissociation over a range of Pd and PdOx surfaces and reve
In order to increase reuse, a number of product versions may be)", developed based on the same software platform. The platform must, however, be managed and updated according to new requirements if it should be reusable in a series of releases. This means that the platform is constantly changed during its lifecycle, and changes can result in degradation of the platform. In this paper, a measuremen
While the inventor is often the driver of an invention in the early stages, he/she needs to move between different social networks for knowledge in order to create and capture value. The main objective of this research is to propose a literature-based framework based on innovation network theory and complemented with C-K theory, in order to analyze the invention/innovation process of inventors and
