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The spread and clinical impact of ST14CC-PBP3 type IIb/A, a clonal group of non-typeable Haemophilus influenzae with chromosomally mediated β-lactam resistance-a prospective observational study

Objectives: Increasing incidences of non-typeable Haemophilus influenzae (NTHi) with β-lactam resistance mediated through mutations in penicillin-binding protein 3 (BLNAR or rPBP3) have been observed in the past decades. Recently, an rPBP3 NTHi sequence type (ST) 14 with PBP3 type IIb/A caused a disease outbreak in a nursing home in Sweden with severe outcomes, indicating increased bacterial virul

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Abstract: This thesis examines the non-dominant and self-subversive aspects of visuality in Roberto Bolaño’s 2666 through the lens of the philosophical discussion on representation, particularly in its post-structuralist context. The present research is grounded in the conviction that 2666 embodies the 20th-century crisis of representation and approaches the novel through an analysis of different

Laparoscopic Roux-en-Y gastric bypass in adolescents with severe obesity (AMOS) : a prospective, 5-year, Swedish nationwide study

BACKGROUND: Severe obesity in adolescence is associated with reduced life expectancy and impaired quality of life. Long-term benefits of conservative treatments in adolescents are known to be modest, whereas short-term outcomes of adolescent bariatric surgery are promising. We aimed to compare 5-year outcomes of adolescent surgical patients after Roux-en-Y gastric bypass with those of conservative

Automated selection of bone texture regions on hand radiographs : Data from the Osteoarthritis Initiative

Manual selection of finger trabecular bone texture regions on hand X-ray images is time-consuming, tedious, and observer-dependent. Therefore, we developed an automated method for the region selection. The method selects square trabecular bone regions of interest above and below the second to fifth distal and proximal interphalangeal joints. Two regions are selected per joint (16 regions per hand)

Oscillator strengths for high-excitation Ti II from laboratory measurements and calculations

This work reports new experimental radiative lifetimes of six 3d2(3F)5s levels in singly ionized titanium, with an energy around 63 000 cm-1 and four 3d2(3F)4p odd parity levels where we confirm previous investigations. Combining the new 5s lifetimes with branching fractions measured previously by Pickering et al., we report 57 experimental log gf values for transitions from the 5s levels. The lif

Bias network and diode parasitics of a reconfigurable stacked microstrip patch antenna at 60 GHz

We present results on the implementation of switches for a reconfigurable antenna at 60 GHz. The switches are realized by diodes, which are characterized by measurements on a coplanar waveguide test bed. From the measurements, we extract different circuit models. The models are used as lumped elements in a full wave simulation of a reconfigurable antenna, where it is shown that the different model

Framework for research on improved life quality

The Sound Environment Center at Lund University has for over ten years hosted interdisciplinary research on sound environment issues promoting an exchange of ideas between researchers through research projects, interdisciplinary symposiums and publications. The center aims at developing a holistic view to a field that is scientifically fragmented. Ranging from acoustics, noise abatement and sounds

Quantitative mass spectrometry to study inflammatory cartilage degradation and resulting interactions with the complement system

Joint diseases are often characterized by inflammatory processes that result in pathological changes in joint tissues, including cartilage degradation and release of components into the synovial fluid. The complement system plays a central role in promoting the inflammation. Because several cartilage proteins are known to interact with complement, causing either activation or inhibition of the sys

Thyroid and islet autoantibodies predict autoimmune thyroid disease already at Type 1 diabetes diagnosis

CONTEXT: Screening of autoimmune thyroid disease in children and young adults with Type 1 diabetes is important but vary greatly between clinics.OBJECTIVE: The aim was to determine the predictive value of thyroid autoantibodies, thyroid function, islet autoantibodies, and HLA- DQ at diagnosis of Type 1 diabetes for autoimmune thyroid disease during subsequent follow-up.SETTING: 43 Paediatric Endoc

Reporting on the State of the Environment: South African Experiences

The past few decades have seen an increasing demand for environmental information on which to make more informed decisions, strengthened by several international calls for improving available environmental information. In a democratic South Africa, the involvement of people in policy and decision-making processes has led to an even greater need for accessible information. In response to this deman

The pig as a model for premature infants - The importance of immunoglobulin supplementation for growth and development

Preterm human neonates, contrary to preterm piglets, obtain immunoglobulins from their mothers via the placenta during intrauterine development. However, one should note that the majority of trans-placental transfer of immunoglobulins in humans takes place during the last trimester of pregnancy. It is also known that the feeding of limited amounts of colostrum or systemic infusion of small amounts

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Inledning I Sverige lever idag 1,5 miljoner – eller mer än en femtedel av den vuxna befolkningen – med en funk­ tionsnedsättning. Många av dessa personer har drabbats av en skada eller sjukdom i hjärnan, ryggmärgen, nerver eller muskler, antingen i barn­ domen eller senare i livet. Skadan eller sjukdomen ger inte bara upphov till ett funktionshinder med påverkan på vardagen utan ökar också risken

https://www.vetenskaphalsa.se/wp-content/uploads/2010/01/05.JanLexell_friskv%C3%A5rd-f%C3%B6r-funktionshindrade.pdf - 2026-05-08

The Use of Non-Destructive Energy Dispersive X-Ray Fluorescence (EDXRF) Analysis for Sourcing Flint in Northern Europe: Progress to Date and Prospects for the Future : Progress to Date and Prospects for the Future

The article summarizes the results of work since 2010 to develop non- destructive energy dispersive X-ray fluorescence analysis (EDXRF) as a non-destructive method for determining the provenience of flint in northern Europe. Some 40 localities from Sweden, Denmark, Germany, Poland, and Ukraine have been sampled and analyzed. Trace elements have not proven particularly effective in drawing distinct

Sensory Relearning and the Plastic Brain

The brain has a tremendous capacity to adapt (i.e., plasticity) to environmental changes or injury. This capacity decreases with age but is never lost. The goal of sensory relearning is to improve hand function by using the dynamic capacity of the brain with the use of guided plasticity (i.e., plasticity used for a therapeutic purpose). After a peripheral nerve injury, no nerve signals are sent fr

New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis

Myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease in rats that closely mimics many clinical and histopathological aspects of multiple sclerosis. Non-MHC quantitative trait loci regulating myelin oligodendrocyte glycoprotein-induced EAE have previously been identified in the EAE-permissive strain, DA, on rat chromosomes 4,10,15, a

Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry

Two monoclonal antibodies (mAb) CB268 and CII-C1 to type 11 collagen (CII) react with precisely the same conformational epitope constituted by the residues ARGLT on the three chains of the CII triple helix. The antibodies share structural similarity, with most differences in the complementarity determining region 3 of the heavy chain (HCDR3). The fine reactivity of these mAbs was investigated by s

Collagen type II is recognized by a pathogenic antibody through germline encoded structures

Collagen type II (CII) is a cartilage-specific target of pathologic humoral autoimmune responses in rheumatoid arthritis as well as in the collagen-induced arthritis model. The aim of the present study is to investigate the critical amino acid residues conferring CII epitope specificity of the prototypic arthritogenic murine mAb CIIC1. A homology model of the CIIC1 single-chain antibody fragment (