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A moment problem and a family of integral evaluations

We study the Al-Salam-Chihara polynomials when q > 1. Several solutions of the associated moment problem are found, and the orthogonality relations lead to explicit evaluations of several integrals. The polynomials are shown to have raising and lowering operators and a second order operator equation of Sturm-Liouville type whose eigenvalues are found explicitly. We also derive new measures with re

Governance arrangements for the implementation of transformative innovation policy : insights from a comparative case study

There has been great interest in the rationales for transformative innovation policies (TIP), including those following a mission-oriented logic. However, few studies have investigated how public administration can effectively implement TIP. To study this, we first identify from existing literature four TIP governance tasks (creating legitimacy and leadership, coordination across levels/instrument

Kulturell identitet och integration: En kvalitativ studie om Fathima projektets arbete med invandrarkvinnor i Sverige

Integration is described as fundamental for immigrants in order for them to establish a normal life in a new and unknown country. Mass migration is a current globally discussed problem, described as a social problem due to increased crime, usually blamed on failed attempts at integration. This study discusses the Swedish Fathima project organized by Save the Children’s Youth Association. The Fathi

Focusing on the heroines in the novels Ivanhoe and The White Company: Peripheral but important

It is now well established that there is a reciprocal relationship between the content of literature and societal norms. Within feminist criticism, this has been highlighted as problematic, as women are often not portrayed fairly. In this essay, I will examine the relationship between literature and society by comparing the 19th-century Medieval novels Ivanhoe (1819) by Sir Walter Scott and The Wh

A Novel C3 Mutation Causing Increased Formation of the C3 Convertase in Familial Atypical Hemolytic Uremic Syndrome.

Atypical hemolytic uremic syndrome has been associated with dysregulation of the alternative complement pathway. In this study, a novel heterozygous C3 mutation was identified in a factor B-binding region in exon 41, V1636A (4973 T > C). The mutation was found in three family members affected with late-onset atypical hemolytic uremic syndrome and symptoms of glomerulonephritis. All three patients

Functionally-associated target antigens in cancer. Defined by human antibodies and small interfering RNAs.

Popular Abstract in Swedish Cancer är ett samlingsnamn på sjukdomar som kännetecknas av okontrollerad celltillväxt. I friskt tillstånd växer kroppens celler kontrollerat. Cancertillståndet startar när någon av dessa celler förändras så att tillväxten ökar. När tillväxten ökar så tilltar också celldelningen. Om ingen åtgärd vidtas kommer cancern till slut att slå ut funktionen hos det organ som denCancer is the collective name for diseases that have one thing in common ? uncontrolled cell growth. The increase in cancer cell proliferation eventually results in tumor formation and, in the worst case, metastatic spread to other organs. Common treatment modalities of cancer include chemotherapy and radiation therapy. However, these methods are associated with severe side effects as well as indu

Acoustical detection of venous stenosis in Hemodialysis patients using principal component analysis

In this paper, a feature extraction method based on principal component analysis was developed for classification of the vascular access’s condition in hemodialysis patients. The assessment of the method was carried out by discriminating between before and after angioplasty sound recordings as well as before angioplasty and reference recordings. The results showed that when before and after angiop

The building process as a tool towards an all-inclusive school. A Swedish example focusing on children with defined concentration difficulties such as ADHD, autism and Down’s syndrome

Professionals who take part in the building process have long been concerned with the same environmental factors, e.g. spatial layout, capacity, and function, as well as user demography. Through the knowledge gained on the ways environmental factors affect users of buildings, the need to understand how to handle these factors has grown, due to their influence on the building process. It will be sh

Antibody Evolution and Repertoire Development

Popular Abstract in Swedish Antikroppar är viktiga beståndsdelar av det naturliga immunförsvaret som skyddar oss mot smittämnen, såsom bakterier och virus. Utvecklingen av olika genetiska och biokemiska teknologier har dessutom möjliggjort användningen av antikroppar för en mängd ändmål, bl a för diagnostik och behandling av infektionssjukdomar och cancer. I denna avhandling, som bygger på fem vetAntibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. Despite tremendous advances in all fields

Att se stjärnor på ljusa dagen. Förvandling och försoning i August Strindbergs En blå bok

Abstract Regnell, Astrid: Att se stjärnor på ljusa dagen. Förvandling och försoning i August Strindbergs En blå bok. Seeing stars in broad daylight. Transformation and Reconciliation in August Strindberg’s Zones of the Spirit. In this thesis a pattern of coherence is explored in August Strindberg’s Zones of the Spirit (En blå bok) – a literary work consisting of a collection of short and quite div

T cells, Cytokines, and Genetic Factors in Autoimmunity Studies of experimental models of arthritis and sialadenitis

Popular Abstract in Swedish Ärftliga orsaker till ledgångsreumatism och Sjögrens syndrom Ett välfungerande immunförsvar är nödvändigt för att kroppen ska kunna mostå angrepp från virus, bakterier och andra mikroorganismer. Vid en autoimmun sjukdom tror man att immunförsvaret av misstag börjar angripa kroppens egna vävnader, vilket leder till att de förstörs. Hur dessa sjukdomar uppkommer känner mTo understand the pathogenesis of autoimmune diseases we have to consider the problem from different angles. Animal models provide a tool to further understand these complex diseases, as the influence of genetic and environmental factors could be limited. Moreover, modern transgenic techniques have made it possible to study the role of certain genes and gene products in the development of diseases

Practical advantages of inverted decoupling

This paper presents a study of the main advantages of inverted decoupling in 2×2 processes. Two simulation examples and an experimental process are used to show these advantages in comparison with simplified decoupling. The study focuses on the following practical advantages: the apparent process is the same as that obtained if one loop changes to manual; bumpless transfer and anti-windup are achi

Determination of Heavy Metals and Fluorine in Airborne Particulate Matter in an Indoor Environment by Simultaneous Use of PIXE and γ-Ray Detection

The current rapid development within work-environment research has created a considerable demand among industrial hygienists for suitable analytical methods. PIXE (particle-induced X-ray emission analysis), which was introduced in Lund in 1970, has been shown to be a feasible method for use in studying the elemental composition of aerosols. However, in some work environments, fluorine, an element

Novel strategies to explore The complex genetics of autoimmune diseases

Popular Abstract in Swedish Autoimmuna sjukdomar såsom reumatoid artrit (RA) och multipel skleros (MS) uppkommer av en felaktig immunrespons mot kroppens egen vävnad. Orsaken är okänd trots enormt mycket forskning om ämnet. Ett sätt att öka kunskapen vore att identifiera de gener som bidrar till sjukdomarna. För sådana relativt vanliga, komplexa sjukdomar finns det inte en gen som ?styr? sjukdomarAutoimmune diseases are dependent on both genetic and environmental factors in complex interplay. They arise from a faulty immune response against self-antigens, and causes great suffering in affected individuals. Despite large efforts and hundreds of thousands of research articles published, the disease etiologies remain largely unknown. Knowledge of which genes are involved and how they interact

Human Factors and Sustainable Development - Some Lessons from Human Factors and Safety Management

Mankind is already spending beyond the capacity of its planet and trends look very scaring. Big changes in human behaviour are urgent. As pointed out by others there are many ways how Ergonomics/Human Factors/ could contribute to such changes. The aim of this paper is to discuss some lessons learnt from safety performance in aviation and trans¬formed to sustainability, especially the concepts sust

Optimization of recombinant in protein production in an E.coli-based process with limited oxygen transfer

E. coli continues to be a popular host organism for production of recombinant proteins. To obtain a high volumetric productivity at the cultivation stage, it is important to achieve a high cell density and a high specific productivity per cell. In many fed-batch processes, the substrate feed rate eventually becomes limited by the oxygen transfer capacity of the bioreactor. While biomass can contin

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.

Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into this question, a panel of mouse monoclonal antibodies was generated against a major triple helical collagen type II (CII) epitope (position 359-369; ARGLTGRPGDA) with or without arginines modified by cit

Solid-to-fluid-like DNA transition in viruses facilitates infection.

Releasing the packaged viral DNA into the host cell is an essential process to initiate viral infection. In many double-stranded DNA bacterial viruses and herpesviruses, the tightly packaged genome is hexagonally ordered and stressed in the protein shell, called the capsid. DNA condensed in this state inside viral capsids has been shown to be trapped in a glassy state, with restricted molecular mo