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Seasonal influenza vaccine effectiveness study in older adults during three influenza seasons (2015-2018) in Lithuania

Background: Due to lack of knowledge about seasonal influenza vaccine effectiveness (SIVE) against laboratory-confirmed influenza in patients aged ≥65 years a study to measure SIVE in patients admitted to hospital due to severe acute respiratory infection (SARI) in Lithuania during the 2015-2018 was conducted.Materials/methods: A test-negative case-control study was performed between 2015-2016 and

Mitogenic effect of alpha 1-microglobulin on mouse lymphocytes. Evidence of T- and B-cell cooperation, B-cell proliferation, and a low-affinity receptor on mononuclear cells

Human alpha 1-m microglobulin (alpha 1-m), a low molecular weight plasma protein, was found to exert mitogenic effects on mouse lymphocytes from lymph nodes and spleen. The stimulatory effects appeared to be strain-restricted: alpha 1-m induced a varying degree of proliferation of lymphocytes from three strains, whereas one strain responded poorly. Experiments with lymphocyte subpopulations showed

We can only do it together: Addressing global sustainability challenges through a collaborative paradigm

Urgent structural change is required in higher education, to allow collaboration both within and across universities, so that achieving rapid sustainability transition can become not only the overarching but the main purpose of education, research and work in society. A review of the literature reveals that fragmentation caused by traditional hierarchical faculty and disciplinary organisation is a

Artificial intelligence in women's cancers : innovation and challenges in clinical translation

Artificial intelligence (AI) is set to transform the care of women with cancer. From early detection via digital phenotyping to diagnosis, treatment, and follow-up, innovative AI applications are rapidly emerging across the cancer care continuum. AI-assisted mammographic screening for breast cancer has been clinically translated, and AI-based contouring in radiotherapy is streamlining treatment pl

Farliga förbindelser: Betydelsen av vänskap, status och suveränitet i diskussioner om svensk allianspolitik 1680–1683

The present study examines the discussions about alliance policy in the Swedish council of the realm 1680-1683. Taking issue with earlier research that has portrayed the Swedish foreign policy during this period in realist terms, the study instead uses the concepts of friendship, status and sovereignty to give context to the arguments used by the council when discussing alliance partners. Regardin

Prosecuting the Russian Aggression – Assessing Proposals to Enable the Prosecution of Russian Leaders for the Crime of Aggression

Den ryska invasionen av Ukraina har orsakat ofattbart mänskligt lidande och har destabiliserat den europeiska säkerhetsordningen. I gengäld har världsledare och internationella organisationer krävt att den ryska aggressionen beivras. Den rättsvetenskapliga debatten om lämpliga åtgärder för att säkerställa straffrättsligt ansvar för aggressionsbrottet har emellertid uppvisat stor oenighet bland forThe Russian invasion of Ukraine has brought immense suffering to the Ukrainian people and has destabilised the European security order. In response, world leaders and international organisations have called for the prosecution of the Russian aggression. However, the scholarly debate on the appropriate measures to ensure criminal accountability for the crime of aggression has demonstrated widesprea

Sex, Love and Moral Control: Exploring the effectiveness and limitations of international and regional human rights law relevant to SOGIESC diverse groups in the quest to invalidate Zimbabwe’s “sodomy” law

“Only in the most technical sense is this a case about who may penetrate whom where. At a practical and symbolical level it is about the status, moral citizenship and sense of self-worth of a significant section of the community.” Justice Albie Sachs, National Coalition for Gay and Lesbian Equality and Another v Minister of Justice and Others 1999 (1) SA 6, para. 107 More than 70 years after th

Digital kompetensutveckling: Intention och digital kompetens i folkbibliotekets internutbildning

Digital literacy has become increasingly important. It's often linked to concepts like the information society, which we use to understand the complex changes in ways we socially and economically organize and run society today. The public library is faced with the task of ensuring that the professional skills of their workforce are in line with what is expected – and also interpreting what is

Det pianistiska lärandet på musik- och kulturskolan - Att uppnå balansen mellan musikaliskt uttryck och pianistiskt hantverk

Hur kan man utforma det pianistiska lärandet hos pianoelever på kommunala musik- och kulturskolan? Frågan ligger centralt för denna uppsats med syftet att undersöka pianopedagogers syn på nödvändiga enheter för att uppnå balansen mellan musikaliskt uttryck och pianistiskt hantverk. I undersökningen framkommer pianopedagogernas grundtankar och strategier för ett helhetsutvecklande pianospel hos eleTitle: The pianistic learning at the Swedish Municipal School of Music and Culture – seeking balance between musical expression and piano technique. How is it possible to design the learning of piano to piano students at the Swedish municipal school of music and culture? This question is central for this paper with the purpose to study piano pedagogues’ thoughts on requisite components for achievi

The Unseen War: Rethinking IHL’s Applicability to Mexico’s Armed Conflict with Drug Cartels

This thesis argues that the escalating and protracted violence in Mexico, commonly known as the ‘war on drugs,’ constitutes a non-international armed conflict (NIAC) under international humanitarian law (IHL), calling for a formal application of this legal framework. Despite its devastating humanitarian consequences, the conflict is often mischaracterised within a law enforcement paradigm, contrib

Strain-Distinct α-Synuclein and Tau Cross-Seeding Uncovered by Correlative Approach with Optical Photothermal Infrared Sub-Micron Imaging

The co-occurrence of α-synuclein (αSyn) and Tau in synucleinopathies and tauopathies suggests a complex interplay between these proteins. Their cross-seeding enhances fibrillization, leading to the formation of diverse amyloid-specific structures enriched with β-sheets, which may influence their biological functions. However, existing tools cannot differentiate structural polymorphs directly in ce