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BACKGROUND: We measured serum levels of human glandular kallikrein 2 (hK2) in patients treated with radical retropubic prostatectomy (rrP) for clinically localized prostate cancer (PCa) with a total PSA (tPSA)-level below 10 ng/ml to investigate whether hK2 can be applied to preoperatively distinguish organ-confined (pT2a/b) from nonorgan-confined (> or = pT3a)-PCa more accurately than total PSA.

The film of sIgA lining the intestinal epithelium plays a role in the regulation of the commensal microflora and prevention of pathogen invasion. We show that, in the absence of intentional immunization, all sIgA in the gut is produced by B-1a B cells. We also show that B-1a B cells and sIgA derive from lineage-negative precursors found in the fetal liver and located in the spleen after birth. The

Background: Few studies have examined how physicians perceive guidelines, much less their perceptions of an Internet presentation of such guidelines. This study assessed physicians' acceptance ofan Internet-based guideline on the appropriateness of colonoscopy. Methods: Gastroenterologists participating in an international observational study consulted an Internet-based guideline for consecutive p

TCR signaling is mediated by intracellular signaling molecules and nuclear transcription factors, which are tightly regulated by interaction with regulatory proteins such as Grb2 and SLAP. We reported recently that TCR stimulation induces the expression of cytokine-induced SH2 protein (CIS). The expression of CIS promotes TCR-mediated activation. We have now found specific interactions between CIS

The vehicle ingress and egress are important issues for the automotive industry, both for minimizing assembly work load and for maximizing end-users’ comfort. Digital human modeling tools are used for evaluating and visualizing these issues. The assembler and end-user are more or less performing the very same entering task if the vehicles have identical geometrical prerequisites. The major differe

Wild-type (F/B), constitutively active (F/B*), and three kinase-inactive (F/Ba-, F/Bb-, F/Bc-) forms of Akt/protein kinase B (PKB) were permanently overexpressed in FDCP2 cells. In the absence of insulin-like growth factor-1 (IGF-1), activities of PKB, cyclic nucleotide phosphodiesterase 3B (PDE3B), and PDE4 were similar in nontransfected FDCP2 cells, mock-transfected (F/V) cells, and F/B and F/B-

Toll-like receptor-4 activation by lipopolysaccharide (LPS) induces the expression of interferon-P (IFN-beta) in a MyD88-independent manner. Here we report that mice devoid of the JAK protein tyrosine kinase family member, Tyk2, were resistant to shock induced by high doses of LPS. Basal and LPS-induced expression of IFN-beta and IFN-alpha4 mRNA in Tyk2-null macrophages were diminished. However, T

Background Preventive programs for individuals who have high lifetime risks of colorectal cancer may reduce disease morbidity and mortality. Thus, it is important to identify the factors that are associated with hereditary colorectal cancer and to monitor the effects of tailored surveillance. In particular, patients with Lynch syndrome, hereditary nonpolyposis colorectal cancer (HNPCC), have an in

Human neutrophil peptide-1 (HNP-1) is a member of the alpha-defensin family. Defensins are cationic antimicrobial peptides, which play an important role in the antimicrobial response to microorganisms. In addition, recent studies have revealed the involvement of defensins in inflammation, immunity and wound repair. Defensins are present in the azurophilic granules of neutrophils and are released u

Knockout of caspase-8, a cysteine protease that participates in the signaling for cell death by receptors of the TNF/nerve growth factor family, is lethal to mice in utero. To explore tissue-specific roles of this enzyme, we established its conditional knockout using the Cre/loxP recombination system. Consistent with its role in cell death induction, deletion of caspase-8 in hepatocytes protected

After infection with Borrelia burgdorferi, humans and mice under certain conditions develop arthritis. Initiation of inflammation is dependent on the migration of innate immune cells to the site of infection, controlled by interactions of a variety of adhesion molecules. In this study, we used the newly synthesized compound S18407, which is a prodrug of the active drug S16197, to analyze the funct

At the End of the World Newsletter – 15 September 2024 This is the seventh newsletter for the  At the End of the World research program, housed at Lund University. It is the third from our second year of activity. If you’re receiving this email, it’s because you’ve been subscribed to our mailing list. Below, we’ll fill you in on some upcoming events for the fall of 2024, and also what we've been u

https://www.endoftheworld.lu.se/at-the-end-of-the-world-newsletter-15-september-2024/ - 2026-05-04

TVSM-5264 Master’s Dissertation Structural Mechanics ANNIE BOHMAN REDUCTION OF EXPLOSION EFFECTS BY USE OF A SANDWICH WALL DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--23/5264--SE (1-70) | ISSN 0281-6679 MASTER’S DISSERTATION Supervisors: Professor KENT PERSSON, Division of Structural Mechanics, LTH and JESPER AHLQUIST, MSc, Sweco Sverige AB. Assistant Sup

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5264.pdf - 2026-05-07

FTEA12:1: Teoretisk filosofi grundkurs, Filosofihistorisk översiktskurs. Denna sammanfattning baseras på 2 utvärderingar från HT11 och 16 utvärderingar från VT12. Litteratur: Sammanfattat så tyckte de flesta att litteraturen var varierande och bra. Follesdahls bok ansågs dock av många som onödig då den låg för nära en annan kursbok. Undervisning: HT11 hade inga klagomål utan skrev endast bra i sin

https://www.fil.lu.se/fileadmin/_migrated/content_uploads/Utvaerderingar_HT11VT12_01.docx - 2026-05-07

7 ingredienser för en godare pension | Sveriges akademikers centralorganisation Hoppa till huvudinnehåll till startsida Öppna sökruta Öppna Huvudmeny Sök på saco.se Om Saco Kontakt Anställda hos Saco Saco studentråd Sacos styrelse Sacos revisorer Sacos organisation Sacos styrelse Kontaktuppgifter Sacos styrelse Verksamhetsberättelse och årsredovisning Federationen och förbunden Medlemsstatistik Fö

https://www.saco.se/studier/saco-studentrad/opinion-och-fakta-saco-studentrad/vad-tycker-saco-studentrad/en-godare-pension/7-ingredienser-for-en-godare-pension/ - 2026-05-07

A K T U E L LT O M V E T E N S K A P O C H H Ä L S A • N O V E M B E R 2014 1 VETENSKAP & HÄLSA AKTUELLT OM POPULÄRVETENSKAPLIGT OM MEDICINSK FORSKNING FRÅN LUNDS UNIVERSITET OCH REGION SKÅNE | NOVEMBER 2014 NÄR HJÄRTAT STANNAR ... INNEHÅLL Fortsätter idrotta efter hjärtstoppet Fredric Medin var bara 25 år när hans hjärta plötsligt stannade mitt under en innebandymatch. I dag lever han som vanligt

https://www.vetenskaphalsa.se/wp-content/uploads/2014/11/Aktuellt-om-vetenskap-och-h%C3%A4lsa-november-2014.pdf - 2026-05-07

Microsoft Word - Preface_060425.doc Licentiate Dissertation Structural Mechanics TORULF NILSSON Report TV SM -3067 TO RU LF N ILSSO N M IC R O M EC H A N IC A L M O D ELLIN G O F N A TU R A L FIB R ES FO R C O M PO SITE M A TER IA LS MICROMECHANICAL MODELLING OF NATURAL FIBRES FOR COMPOSITE MATERIALS Detta är en tom sida! Copyright © 2006 by Structural Mechanics, LTH, Sweden. Printed by KFS I Lund

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm3000/web3067.pdf - 2026-05-08

Brevmall Vårterminen 2021 Språk- och l i t te raturcent rum Kurslitteratur för: FÖUN02, Översättning till svenska 1 (12 hp) FÖUS01, Översättning till svenska 1 (15 hp) FÖUN05, Översättning till svenska 2 (7,5 hp) FÖUN17, Översättning till svenska 3 (15 hp) FÖUN19, Översättning från ett andra källspråk (15 hp) Fastställd av styrelsen för sektion 1 vid Språk- och litteraturcentrum, den 17 juni 2020.

https://www.sol.lu.se/media/utbildning/dokument/kurser/FOUN05/20211/FOUN_02_05_17_19_inkl_kinesiska.pdf - 2026-05-08