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Failure Analysis With a New Tool Geometry, X-Die, in Areas With High Tension/Compression Strains

Sheet-metal forming involves a complex strain distribution over the part. The strains consist of tension, compression, and a mix of both. A geometry has been developed, the X-Die, in order to gain insight into the strain behavior of different materials. The X-Die enables strain paths far into the tension/compression region, thus creating the possibility to extend the experimental base both for def

Relationships between housing and healthy aging in very old age

Purpose: The aim of this work is to examine the relationship between aspects of objective and perceived housing and aspects of healthy aging, defined as independence in daily activities and subjective wellbeing. Furthermore, this research examined the comparability of relationships between housing and healthy aging in the five European countries. Design and Methods: Data were drawn from the ENABLE

The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

Popular Abstract in Swedish Varje år insjuknar mer än 8000 kvinnor i Sverige i bröstcancer, och 5 år efter diagnos är nära 90% fortfarande i livet. Trots att prognosen för majoriteten av patienterna är god, dör 1400 kvinnor årligen av bröstcancer. Till följd av detta pågår mycket forskningsarbete för att finna faktorer som bättre kan förutsäga prognos, prognostiska studier, men även för att finna Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. At the same time, a substantial number of patients will be over-treated, as they would have been cured by surgery and radiotherapy alone. In the meta

Exploring History: a Mobile Inclusive Virtual Tourist Guide

In the present paper we report on the design decisions and the field test results of an inclusive mobile tourist guide app, the Time Machine. The historical information is conveyed by sound and the navigation information by haptics, while the app can be controlled eyes-free by a combination of on-screen and free-form gestures. To emphasize the eyes-free use, 9 of 11 test users recruited had severe

Random Number Generation by Chaotic Double Scroll Oscillator on Chip

Generation of good non-repeatable and non-predictable random number sequences is of increasing importance, both in security applications and in simulations. A novel, compact system is presented in which a secure random number is generated by sampling a chaotic system and using this bitstream as the input to a pseudo-random generator. An optional hash function can be used on the seed in order to de

The Visual Representation of Gender in Illustrated Children’s Books in Iran and Sweden Today : A study of ‘The lover and Sanam’ and ‘That’s what a princess does’

Since culture has been changing over the time in all of the societies, the notions of gender and sex-role stereotypes as two of the constitutive parts of culture have been altering as well; due to the development of contemporary movements such as feminism and gender-related discourses. Nevertheless, because of different social environments and different rituals and values the development pace and

Increased GABA(A) channel subunits expression in CD8(+) but not in CD4(+) T cells in BB rats developing diabetes compared to their congenic littermates

GABA (gamma-aminobutyric acid), the main inhibitory neurotransmitter in the central nervous system is also present in the pancreatic islet beta cells where it may function as a paracrine molecule and perhaps as an immunomodulator of lymphocytes infiltrating the pancreatic islet. We examined CD4(+) and CD8(+) T cells from diabetes prone (DRlyp/lyp) or resistant (DR+/+) congenic biobreeding (BB) rat

Combining apps targeting professionals and senior citizens to improve housing accessibility and influence housing provision policies.

Two separate apps that address the increasingly important issue of accessible housing for senior citizens have been developed in different project settings. One of the apps was developed to facilitate the process for professional raters to assess housing accessibility in the context of individual housing adaptations. The other app was developed for senior citizens to raise their awareness of possi

Early Blood Cell Formation "in sickness and health, ´till death do us part"

Hematopoietic stem cells (HSC), the ancestors of all blood cells, have the ability to give rise to mature effector cells through a series of developmental steps. This is a tightly regulated, though a highly dynamic process: on the one hand, dysregulation in steady-state could lead to under- or overgrowth of certain blood cell lineages, whereas, on the other hand, demands for certain mature blood c

A novel method for direct measurement of complement convertases activity in human serum.

Complement convertases are enzymatic complexes that play a central role in sustaining and amplification of the complement cascade. Impairment of complement function directly or indirectly leads to pathologic conditions including higher infection rate, kidney diseases, autoimmune- or neurodegenerative diseases and ischemia-reperfusion injury. An assay for direct measurement of activity of the conve

Evolution of UV-B regulation and protection in plants

Plants have evolved under the influence of UV-B radiation and have acquired systems for monitoring it and investing appropriate resources for protection against it, i.e., filters, quenchers of radicals and reactive oxygen species, and repair systems. An hypothesis for how plants monitor radiation has been presented.

ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis

Background The diagnosis of atopic dermatitis (AD) is made using evaluated clinical criteria. Management of AD must consider the symptomatic variability of the disease. Methods EADV eczema task force developed its guideline for atopic dermatitis diagnosis and treatment based on literature review and repeated consenting group discussions. Results and Discussion Basic therapy relies on hydrating top

Critical Comparison of Multidimensional Separation Methods for Increasing Protein Expression Coverage

We present a comparison of two-dimensional separation methods and how they affect the degree of coverage of protein expression in complex mixtures. We investigated the relative merits of various protein and peptide separations prior to acidic reversed-phase chromatography directly coupled to an ion trap mass spectrometer. The first dimensions investigated were density gradient organelle fractionat

Adherence to isoniazid preventive therapy in children exposed to tuberculosis: a prospective study from Guinea-Bissau

OBJECTIVE: To assess adherence to isoniazid preventive therapy (IPT) in children exposed to adult pulmonary tuberculosis (TB) at home. METHODS: Children were enrolled on IPT if they were aged <= 5 years or 5-15 years and presented a tuberculin skin test induration of >= 1.0 mm. Children were included from the demographic surveillance system of the Bandim Health Project in Bissau, Guinea-Bissau. Th

Human Papillomavirus Antibody Reference Reagents for Use in Postvaccination Surveillance Serology

Suitably controlled serosurveillance surveys are essential for evaluating human papillomavirus (HPV) immunization programs. A panel of plasma samples from 18-year-old females was assembled, the majority of the samples being from recipients of the bivalent HPV vaccine. Antibody specificities were evaluated by three independent laboratories, and 3 pools that displayed no antibodies to any HPV type t

High levels of immunoglobulin E and a continuous increase in immunoglobulin G and immunoglobulin M by age in children with newly diagnosed type 1 diabetes

The incidence of type 1 diabetes (T1D) is increasing, either because of environmental factors accelerating onset of the disease or because of inducement of autoimmune diabetes in children who previously were at lower risk. High levels of immunoglobulin (Ig), specifically, IgM and IgA, and a low level of IgG were reported in adult patients; however no studies have analyzed the increasing incidence

Image-based localization using hybrid feature correspondences

Where am I and what am I seeing? This is a classical vision problem and this paper presents a solution based on efficient use of a combination of 2D and 3D features. Given a model of a scene, the objective is to find the relative camera location of a new input image. Unlike traditional hypothesize-and-test methods that try to estimate the unknown camera position based on 3D model features only, or

System Identification using LQG-Balanced Model Reduction,

System identification of linear multivariable dy-namic models based on discrete-time data can be performed using a algorithm combining linear regression and LQG-balanced model reduction. The approach is applicable also to unstable system dynamics and it provides balanced models for optimal linear prediction and control.

Solving large scale binary quadratic problems: Spectral methods vs. Semidefinite programming

In this paper we introduce two new methods for solving binary quadratic problems. While spectral relaxation methods have been the workhorse subroutine for a wide variety of computer vision problems - segmentation, clustering, image restoration to name a few - it has recently been challenged by semidefinite programming (SDP) relaxations. In fact, it can be shown that SDP relaxations produce better

Tradition Making and Tradition Breaking : Female students' Perspectives on Education

Female students' traditional and non-traditional choices of education is the subject of this study. Facing difficult choices on different levels of the educational system girls often, statistically, make traditional choices, but they also in different ways break traditional patterns. The study takes its starting-point in the following issues: What is the girls' understanding of the formal liberty