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Structure-Guided Design of d -Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain

Galectin-8 is a carbohydrate-binding protein that plays a crucial role in tumor progression and metastasis, antibacterial autophagy, modulation of the immune system, and bone remodeling. The design, synthesis, and protein affinity evaluation of a set of C-3 substituted benzimidazole and quinoline d-galactal derivatives identified a d-galactal-benzimidazole hybrid as a selective ligand for the gale

Parallel Worlds in British Fantasy Film

The thesis deals with the representation of fantasy in modern film with special regards to parallel-world stories. In order to demarcate parallel worlds from other types of magical worlds in fantasy stories, the thesis contains an extensive chapter of definitions. Starting out with Todorov’s and Jackson’s well-known theories on fantasy / the fantastic, the thesis turns to other approaches allowing

The "Omnipresent" Consul: George Logie and Swedish entanglement along the Mediterranean maritime frontier in the 18th century

Uppsatsens syfte är att undersöka den tidigare outforskade svenska konsuln i Alger, George Logie (1694-1776), och sammanflätningen av aktörer som var drivande bakom den kommersiella expansionen i Medelhavet efter Stora nordiska krigets slut. Expansionen resulterade i ökad handel med en infrastrukturell etablering av flertalet konsulat, vilket ledde vidare till utökat utbyte mellan Nordeuropa, Mede

Observation of an Associative State in Aqueous Hydroxide

The dynamics of chemical reactions in solution are of paramount importance in fields ranging from biology to materials science. Because the hydrogen-bond network and proton dynamics govern the behavior of aqueous solutions, they have been the subject of numerous studies over the years. Here, we report the observation of a previously unknown associative state in the hydroxide ion that forms when a

A green dry route for antibacterial nanofinishing of textiles

In this paper, an aerosol-based process is proven for imparting antibacterial property to textiles. Nanoparticles of copper and silver are produced by means of glow discharge between two electrodes in nitrogen at atmospheric pressure and passed through fabrics of cotton and polyester which act as filter media. The bactericidal performance of the nanofinished fabrics is assessed against Gram-positi

Active bacterial modification of the host environment through RNA polymerase II inhibition

Unlike pathogens, which attack the host, commensal bacteria create a state of friendly coexistence. Here, we identified a mechanism of bacterial adaptation to the host niche, where they reside. Asymptomatic carrier strains were shown to inhibit RNA polymerase II (Pol II) in host cells by targeting Ser2 phosphorylation, a step required for productive mRNA elongation. Assisted by a rare, spontaneous

Impact of agricultural water management on lake water budget : A case study of Lake Ikeda, Japan

Hydrological assessment of the effect of water utilization on a lake water budget isindispensable for proper water management. A model to estimate lake water level was developed for Lake Ikeda, Japan, and was applied to investigate the lake water budget and to examine the effect of agricultural water management on the lake water level. The calculated lake water levels agreed well with the measured

Increased antibody levels to stage-specific Epstein–Barr virus antigens in systemic autoimmune diseases reveal a common pathology

The immune responses to antigens from different stages of the Epstein–Barr virus (EBV) life cycle were investigated in systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren’s syndrome (SS), and systemic sclerosis (SSc) to gain knowledge of EBV’s involvement in the etiology of systemic autoimmune diseases (SADs) and for an overview of the humoral immune responses against EBV. Inves

Galactic Archeology with 4MOST

4MOST is a new wide-field, high-multiplex spectroscopic survey facility for the VISTA telescope of ESO. Starting in 2022, 4MOST will deploy 2400 fibres in a 4.1 square degree field-of-view using a positioner based on the tilting spine principle. In this contribution we give an outline of the major science goals we wish to achieve with 4MOST in the area of Galactic Archeology. The 4MOST Galactic Ar

Inflammation-profiling reveals activated pathways and biomarkers with predictive potential in oligoarticular juvenile idiopathic arthritis

Background: We set out to profile the immune mechanisms active in treatment-naïve oligoarticular JIA (oJIA) to improve the knowledge of its immunopathogenesis, to identify potential biomarkers that can aid diagnosis, predictions and that correlate with clinical disease parameters. Methods: Using Olink proteomics (inflammation panel measuring 92 markers), we defined and compared the inflammation pr

Human papillomavirus-related squamous cell carcinomas after blood or marrow transplantation - a Blood or Marrow Transplant Survivor Study report

Background Human papillomavirus (HPV) is associated with an increased risk for a variety of squamous cell carcinomas in the general population. The risk for subsequent squamous cell carcinomas in blood or marrow transplantation survivors that are potentially related to HPV (cervical, oropharyngeal, vulvar, vaginal, anal, and penile cancer; HPV-related squamous cell carcinomas) remains unknown. Met

Control strategy to mitigate line voltage flicker of commercial high-power capacitor chargers for pulsed power applications

Modern solid-state klystron modulators generate high-voltage, high-power pulses by discharging energy stored in a capacitor bank. Such modulators require at least one capacitor charging unit supplying the energy released in pulsing. Traditional capacitor charging structures rely on AC/DC front-end units based on passive diode rectifiers in conjunction with high-frequency resonant converters. Howev

HARPS-N, TESS, and CHEOPS∗ discover a transiting sub-Neptune and two outer companions around the bright solar analogue HD 85426

We provide a detailed characterization of the planetary system orbiting HD 85426 (TOI-1774). This bright G-type star (: 0.99;: 1.13; age: 7.4 Gyr; V mag: 8.25) hosts a transiting sub-Neptune, HD 85426 b, with an orbital period of 16.71 d and a blackbody equilibrium temperature of K. By jointly analysing HARPS-N RVs, TESS, and CHEOPS photometric data and using two different stellar activity mitigat

Inledning.indd

Inledning.indd 1 Per Erik Ljung Lunds universitet Per_Erik.Ljung@litt.lu.se Inledning: Mönster och möjligheter i studiet av översättning Det nns inget självklart sätt att skapa överblick över de 133 texter som här publiceras. Visserligen skapades en viss ordning genom de frågor vi gick ut med i vårt Call for papers inför konferensen, men ord- ningen kan som alltid vara rätt bedräglig. Vi frågade e

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/introduction_v5_se.pdf - 2026-05-11

Realkatalogen

Realkatalogen E. M Ä N N I S K A N I. Människans egenskaper. A.Kroppsliga egenskaper. ...................... 1.Individ och folktyp. a.Typ. Jfr fotografier kap. E. b.Utseende och gestalt. Jfr F III:7a; I IX:1q; I VI:Bli; E II:6Cb; I V:1; G V:5b. c.Hållning, uppträdande. d.Prestationsförmåga. Jfr B II:+6. Motståndskraft, härdning. Jfr E II:4d. Arbetsförmåga. Jfr E II:4e,5Bc. Starka. Pottebo here. e.

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/register/real_e.pdf - 2026-05-14

No title

LUNDS UNIVERSITET HT-fakulteterna Forskningsnämnden PROTOKOLL Diarienummer STYR 2025/439 Sammanträdesdatum 2025-02-04, kl. 9.15-11.20 Forskningsnämndens sammanträde 2025-02-04 Ledamöter Närvarande Niclas Burenhult, professor Anamaria Dutceac Segesten, docent, ordförande Harry Juhlin, student Sanne Krogh Groth, docent Freja Lauridsen, doktorand Paul Tenngart, docent Johan Östling, professor Frånvar

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/protokoll/FON/Protokoll_FON_2025.pdf - 2026-05-14