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Extraction of vitamin D, including its hydroxylated and esterified metabolites, from soft tissues such as the liver is challenging due to the lipophilic character of matrix and analytes that are expected in very low concentration levels. In this study, we aimed at the optimization of two-step extraction using solid–liquid extraction as the first step, followed by solid-phase extraction. Various so

Fat-soluble vitamin D is an essential bioactive compound important for human health. Insufficient vitamin D levels can result not only in bone disease but also in other disorders, such as cancer, metabolic disorders, and diseases related to poor immune function. The current methods commonly used for vitamin D analysis are often applied to determine the levels of the most abundant metabolite in pla

Flatness of the loss curve around a model at hand has been shown to empirically correlate with its generalization ability. Optimizing for flatness has been proposed as early as 1994 by Hochreiter and Schmidthuber, and was followed by more recent successful sharpness-aware optimization techniques. Their widespread adoption in practice, though, is dubious because of the lack of theoretically grounde

Ultra-f aint dw arf galaxies (UFDs) are commonly found in close proximity to the Milky Way and other massive spiral galaxies. As such, their projected stellar ellipticity and extended light distributions are often thought to owe to tidal forces. In this paper, we study the projected stellar ellipticities and faint stellar outskirts of tidally isolated ultra-faints drawn from the 'Engineering Dwarf

Corded Ware is one of the main archaeological phenomena of the third millennium before the common era (BCE), with a wide geographic spread across much of central and northeastern Europe, from Denmark, the Rhineland, and Switzerland in the west to the Baltic and Western Russia in the east, and broadly restricted to the temperate, continental zones north of the Alps, the Carpathians, and the steppe/

Adipose-derived lipid droplets (LDs) are rich in triacylglycerols (TAGs), which regulate essential cellular processes, such as energy storage. Although TAG accumulation and LD expansion in adipocytes occur during obesity, how LDs dynamically package TAGs in response to excessive nutrients remains elusive. Here, we found that LD lipidomes display a remarkable increase in TAG acyl chain saturation u

Existing datasets for autonomous driving (AD) often lack diversity and long-range capabilities, focusing instead on 360° perception and temporal reasoning. To address this gap, we introduce Zenseact Open Dataset (ZOD), a large- scale and diverse multimodal dataset collected over two years in various European countries, covering an area 9×that of existing datasets. ZOD boasts the highest range and

PURPOSE: Distal ulnar Hounsfield unit (HU) measurements obtained from computed tomography (CT) scans of the wrist can be used to accurately screen for low bone mineral density. It is unknown whether HU measurements can also predict the risk of future fragility fractures. Therefore, the purpose of this study was to determine if the HU values of the distal ulna correlate to fragility fracture risk.M

BACKGROUND: A significant proportion of patients with ST-segment– elevation myocardial infarction (MI) have no standard modifiable cardiovascular risk factors (SMuRFs) and have unexpected worse 30-day outcomes compared with those with SMuRFs. The aim of this article is to examine outcomes of patients with non–ST- segment– elevation MI in the absence of SMuRFs. METHODS AND RESULTS: Presenting featu

CONTEXT: Minipuberty, a period of a transient activation of the hypothalamic-pituitary-gonadal (HPG) axis in both sexes, enables evaluation of gonadal function in infants suspected of hypogonadism. However, female minipuberty remains poorly elucidated. OBJECTIVE: We aimed to establish continuous reference ranges for the most commonly used reproductive hormones and to evaluate the dynamics of the H

Diverse organophosphate hydrolases have convergently evolved the ability to hydrolyse man-made organophosphates. Thus, these enzymes are attractive model systems for studying the factors shaping enzyme functional evolution. Methyl parathion hydrolase (MPH) is an enzyme from the metallo-β-lactamase superfamily, which hydrolyses a wide range of organophosphate, aryl ester and lactone substrates. In

Non-islet cell tumor hypoglycemia (NICTH) is one of the paraneoplastic syndromes manifesting severe hypoglycemia caused by aberrant production of high-molecular-weight insulin-like growth factor 2 (big-IGF2). Two surgical cases of extremely large thoracic solitary fibrous tumors (SFT) with unusual history of NICTH are presented. One case manifested severe hypoglycemia after four years of the first

Clinical mental health researchers may understandably struggle with how to incorporate biological assessments in clinical research. The options are numerous and are described in a vast and complex body of literature. Here we provide guidelines to assist mental health researchers seeking to include biological measures in their studies. Apart from a focus on behavioral outcomes as measured via inter

To generate the required antiproton beam intensity for the FAIR PANDA experiment, a dedicated proton LINAC (pLINAC) for the FAIR accelerator chain is being constructed. Klystron modulators are power converters within the high-power RF system of the pLINAC. Here, seven modulator systems with a nominal pulse power amplitude of 115 kV / 54 A, an effective pulse width of 360 µs and a pulse repetition

Electrostatic energy plays a pivotal role in the minimization of the free energy of self-assembling oppositely charged ions. This is a fundamental principle that guides the formation of aggregates and the separation of phases characterized by a stoichiometric balance between the opposite charges. However, this study unveils the self-assembly of catanionic nanotubes from a mixture of oppositely cha

The discourse on beauty has primarily been focused on the white gaze to prescribe its normative standards. The white gaze conceptualizes the way in which beauty is dwelled on within society: the foisting of Caucasian-looking beauty canons on black women, and the veneration of whiteness as superior. Black bodies are vanguards, either being desired or erased. In literature, the expression “white gaz

PooleHeather_etal_mod The 2nd EuroSoTL conference, June 8-9 2017, Lund, Sweden Disrupting the calendar: Measuring the impacts of a week- long fall break on stress and academic success in undergraduate students H. Poole, University of Ottawa, A. Khan, M. Agnew, I. Ghilic, and A. Smith, McMaster University ABSTRACT: The mental health of post-secondary students has received recent attention as popula

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Poole_etal.pdf - 2026-05-16

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https://www.student.lth.se/kurs-och-programinformation/praktik-i-naeringslivet/praktikkurs-ingenjoersyrkespraktik/ - 2026-05-16

Arab Jurisprudence in the Application of International Human Rights Conventions 1 Table of Contents Abbreviations 5 Preamble 6 1. Introduction 8 1.1. Methodology 10 2. General Theoretical Framework for the Role of the Judiciary in the Application of International Human Rights Instruments 14 2.1. The Concept of Judicial Oversight and its Role in the Protection of Human Rights from the Perspective o

https://rwi.lu.se/app/uploads/2016/09/English-version-Arab-Jurisprudence-in-the-Application-of-International-Human-Rights-Conventions.pdf - 2026-05-16