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Precision Diagnostics in Myeloid Malignancies : Development and Validation of a National Capture-Based Gene Panel

Gene panel sequencing has become a common diagnostic tool for detecting somatically acquired mutations in myeloid neoplasms. However, many panels have restricted content, provide insufficient sensitivity levels, or lack clinically validated workflows. We here describe the development and validation of the Genomic Medicine Sweden myeloid gene panel (GMS-MGP), a capture-based 191 gene panel includin

Protocolized reduction of non-resuscitation fluids versus usual care in septic shock patients (REDUSE) : a randomized multicentre feasibility trial

BACKGROUND/PURPOSE: Non-resuscitation fluids constitute the majority of fluid administered for septic shock patients in the intensive care unit (ICU). This multicentre, randomized, feasibility trial was conducted to test the hypothesis that a restrictive protocol targeting non-resuscitation fluids reduces the overall volume administered compared with usual care.METHODS: Adults with septic shock in

Standardised and automated assessment of head computed tomography reliably predicts poor functional outcome after cardiac arrest : a prospective multicentre study

Purpose: Application of standardised and automated assessments of head computed tomography (CT) for neuroprognostication after out-of-hospital cardiac arrest. Methods: Prospective, international, multicentre, observational study within the Targeted Hypothermia versus Targeted Normothermia after out-of-hospital cardiac arrest (TTM2) trial. Routine CTs from adult unconscious patients obtained > 48 h

Sedation, temperature and pressure after cardiac arrest and resuscitation—The STEPCARE trial: A statistical analysis plan

Background: Basic management for patients who have suffered a cardiac arrest and are admitted to an intensive care unit (ICU) after resuscitation includes setting targets for blood pressure and managing sedation and temperature. However, optimal targets and management are unknown. Methods: The STEPCARE (Sedation, Temperature and Pressure after Cardiac Arrest and Resuscitation) trial is a multicent

Risk of complications in patients with conservatively managed ovarian tumours (IOTA5) : a 2-year interim analysis of a multicentre, prospective, cohort study

Background: Ovarian tumours are usually surgically removed because of the presumed risk of complications. Few large prospective studies on long-term follow-up of adnexal masses exist. We aimed to estimate the cumulative incidence of cyst complications and malignancy during the first 2 years of follow-up after adnexal masses have been classified as benign by use of ultrasonography. Methods: In the

High Levels of Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Carotid Plaque Inflammation and Increased Risk of Ischemic Stroke

Background When the lectinlike oxidized low-density lipoprotein (ox LDL) receptor-1 ( LOX -1), a scavenger receptor for ox LDL , binds ox LDL , processes leading to endothelial dysfunction and inflammation are promoted. We aimed to study release mechanisms of LOX -1 and how circulating levels of soluble LOX -1 ( sLOX -1) relate to plaque inflammation and future risk for ischemic stroke. Methods an

A clonal expression biomarker associates with lung cancer mortality

An aim of molecular biomarkers is to stratify patients with cancer into disease subtypes predictive of outcome, improving diagnostic precision beyond clinical descriptors such as tumor stage1. Transcriptomic intratumor heterogeneity (RNA-ITH) has been shown to confound existing expression-based biomarkers across multiple cancer types2–6. Here, we analyze multi-region whole-exome and RNA sequencing

Protocolized REDUction of Non-Resuscitation Fluids in SEptic Shock Patients. A Protocol for the REDUSE Randomized Clinical Trial

In septic shock, administration of large fluid volumes is associated with poor outcomes. Recent evidence shows that non-resuscitation fluids are the major modifiable source of fluids for patients with septic shock in intensive care units (ICUs). This clinical trial is designed to test the hypothesis that restrictive administration of non-resuscitation fluids improves outcomes compared to usual car

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Abstracts Castle and Comfort: Everyday Life in Scandinavian Castles 1050 –1660 27 – 29 April 2026, Lund University Gardens for health, leisure and cellarium Anna Andréasson Sjögren, Arkeologerna/SHM A particular range of gardens were important parts of the medieval castle milieu, providing environments for leisure and social interaction as well as areas for making different kinds of produce, neede

https://konferens.ht.lu.se/fileadmin/user_upload/conference/castle_and_comfort/Alla_abstractC_C260407.pdf - 2026-05-23

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Master’s Dissertation Structural Mechanics Report TV SM -5233 BJÖ RN PED ERSEN C O N C EPTU A L D Y N A M IC A N A LY SIS O F A V EH IC LE B O D Y BJÖRN PEDERSEN CONCEPTUAL DYNAMIC ANALYSIS OF A VEHICLE BODY 5233HO.indd 15233HO.indd 1 2018-10-19 15:37:512018-10-19 15:37:51 DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--18/5233--SE (1-103) | ISSN 0281-6679 MA

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5233.pdf - 2026-05-23

Årsberättelse 2023 LTH

Årsberättelse 2023 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET Årsberättelse 2023 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET ·• au I LTH:s förbränningsmotorlabb. Avdelningen för förbränningsmotorer har länge varit en av de internationellt ledande grupperna inom för- bränningskoncept som minskar motorernas bränsleförbrukning och skadliga avgasutsläpp. Foto: Charlotte Carlberg Bärg 3 Ti

https://www.lth.se/fileadmin/lth/omlth/vb/TA_A__rsbera__ttelse2023_LTH.pdf - 2026-05-23

CURRICULUM VITAE OF THE APPLICANT

CURRICULUM VITAE OF THE APPLICANT Curriculum Vitae (2023) Prof. Erik J. Olsson Born: 1964 Present employment: Full Professor in Theoretical Philosophy, Lund University, Sweden Citizenship: Sweden Career in brief 1984-1992 Studies in Philosophy, Linguistics, Mathematics and Computer Science at Uppsala University, Sweden 1989-1996 Technical market analyst (main customer: Canadian Embassy in Stockhol

https://www.fil.lu.se/media/documents/persons/ErikJOlsson/CV_Erik_J_Olsson_2023.pdf - 2026-05-23

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Climate Mobility and Human Rights : A Monitoring Toolkit for NHRIs 2 Climate Mobility and Human Rights: A Monitoring Toolkit for NHRIs Raoul Wallenberg Institute of Human Rights and Humanitarian Law (RWI) is a research and academic institution committed to human rights education and development across the world. Informed by over 30 years of research and direct engagement experience, our current or

https://rwi.lu.se/wp-content/uploads/2025/06/20250530_Human-Rights-Based-Approach-to-Climate-Change-and-Mobility-Toolkit-for-NHRIs_wo-CH-23_Thun-Design.pdf - 2026-05-24

arkstudier – Sida 7 – STUDIEVÄGLEDARBLOGGEN

arkstudier – Sida 7 – STUDIEVÄGLEDARBLOGGEN Hoppa till huvudinnehåll Hem Studievägledaren vid Institutionen för arkeologi och antikens historia i Lund Lära sig vara student Sök Sök Stäng Meny Meny STUDIEVÄGLEDARBLOGGEN Blandad information för studenter på Institutionen för arkeologi och antikens historia vid Lunds universitet arkstudier Sida 7 / 34 29 januari, 2024 | arkstudier Tredje veckan på te

https://arkstudier.blogg.lu.se/author/arkstudier/page/7/ - 2026-05-24

23MOD_Proceedings-lydia-carling-final

23MOD_Proceedings-lydia-carling-final LTH:s 12:e Pedagogiska Inspirationskonferens, 7 december 2023 Abstract—Hållbar utveckling är ett ord som kommer att prägla alla ingenjörers framtida arbetsliv. För att tillgodose kunskapsbehovet har LTH som examenskrav att civilingenjörer ska genomgå utbildning om hållbar utveckling, ofta genom en enskild kurs. Men i vilken utsträckning påverkar denna kurs vad

https://www.lth.se/fileadmin/cee/genombrottet/konferens2023/B2_Carling.pdf - 2026-05-24

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– en rapport om lågkonjunkturens effekter Över 100 000 arbetslösa akademiker Över 100 000 arbetslösa akademiker - en rapport om lågkonjunkturens effekter Gilbert Fontana © Gilbert Fontana och Saco 2025 www.saco.se http://www.saco.se/ 2 Sammanfattning Sveriges svaga konjunktur märks allt tydligare på arbetsmarknaden. Sedan sommaren 2023 har arbetslösheten gradvis ökat, även bland högutbildade som v

https://www.saco.se/contentassets/a127f8576f9a4598b1ba62279526380b/over-100-000-arbetslosa-akademiker---en-rapport-om-lagkonjunkturens-effekter.pdf - 2026-05-24

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Chefernas inställning till lönesättande samtal vid Lunds universitet Rapportförfattare Adam Brenthel (PhD), ordf. Saco-S-rådets styrelse vid Lunds universitet. Statistiken och figurerna har gjorts av Roger Senden. Malin Nilsson och Helene Castenbrandt har bistått författaren. 2 INLEDNING ...............................................................................................................

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/lunds-universitet/dokument/rapporten-om-chefernas-installning-till-lonesattande-samtal-vid-lunds-universitet.pdf - 2026-05-24

Advanced organoid models for targeting Kras-driven lung adenocarcinoma in drug discovery and combination therapy

BACKGROUND: Lung cancer remains one of the most challenging diseases to treat due to its heterogeneity. Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) mutations are genetic drivers in numerous cancer types including lung adenocarcinoma (LUAD). Despite recent advances in KRAS-targeted therapies, treatment resistance and limited therapeutic options necessitate advanced preclinical models, such as

In vivo dendritic cell reprogramming for cancer immunotherapy

Immunotherapy can lead to long-term survival for some cancer patients, yet generalized success has been hampered by insufficient antigen presentation and exclusion of immunogenic cells from the tumor microenvironment. Here, we developed an approach to reprogram tumor cells in vivo by adenoviral delivery of the transcription factors PU.1, IRF8, and BATF3, which enabled them to present antigens as t

Realkatalogen

Realkatalogen M. DIKTNING I. Sagor. (Grupperna 2-9 av sagorna äro ordnade enligt följande system: a. Typer enligt Aarne-Thomsom Types of the Folk-tale. b. Thompsons komplement. c. Andra typer. 1. Allmänna uppgifter. 2. Djursagor. 3. Undersagor. 4. Legendsagor. Jfr F IV:C3; H2a. 5. Novellsagor. 6. Sagor om dum djävul (jätte). 7. Skämtsagor. 8. Lögnsagor. Jfr B II:+11c; B III:+12,+13. 9. Kedjesagor.

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/register/real_m.pdf - 2026-05-21