Sökresultat

BACKGROUND: Proper treatment of lymph node-negative breast cancer depends on an accurate prognosis. To improve prognostic models for this disease, we evaluated whether an immunohistochemical marker for proliferating cells, Ki-S2 (a monoclonal antibody that binds to a 100-kd nuclear protein expressed in S, G2, and M phases of the cell cycle), is an accurate indicator of prognosis.METHODS: We studie

BACKGROUND: Pathways for intravenously administered gadolinium-based-contrast-agents (GBCAs) entering cerebrospinal-fluid (CSF) circulation in the human brain are not well-understood. The blood-CSF-barrier (BCSFB) in choroid-plexus (CP) has long been hypothesized to be a main entry-point for intravenous-GBCAs into CSF. Most existing studies on this topic were performed in animals and human patient

Type 1 diabetes (T1D) is an autoimmune disease that targets pancreatic islet beta cells and incorporates genetic and environmental factors1, including complex genetic elements2, patient exposures3 and the gut microbiome4. Viral infections5 and broader gut dysbioses6 have been identified as potential causes or contributing factors; however, human studies have not yet identified microbial compositio

Due to its proximity, the Orion star forming region is often used as a proxy to study processes related to star formation and to observe young stars in the environment they were born in. With the release of Gaia DR2, the distance measurements to the Orion complex are now good enough that the 3D structure of the complex can be explored. Here we test the hypothesis that, due to non-trivial structure

CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. OBJECTIVE: To investigate comorbidities in patients with CD. DESIGN, SETTING, AND PATIENTS: A retrospective, nationwide study of patients with CD identified in the Swedish National Patient Register between 1987 and 2013. Individual medical records were reviewed to ver

The processes that led to the formation of the planetary bodies in the Solar system are still not fully understood. Using the results obtained with the comprehensive suite of instruments onboard the European Space Agency's Rosetta mission, we present evidence that comet 67P/Churyumov-Gerasimenko likely formed through the gentle gravitational collapse of a bound clump of mm-sized dust aggregates ('

In this thesis diet and health of people who lived in southern Sweden 2300-1100 BCE is studied. The study is based on bioarchaeological analyses of human remains from 46 localities in the areas of Uppland, Närke, Östergötland, Västergötland, and Scania. The studies are based on skeletal remains from a minimum number of 310 individuals that have been analysed both osteologically and biochemically.

Background: Cluster analyses have proposed different diabetes phenotypes using age, BMI, glycaemia, homoeostasis model estimates, and islet autoantibodies. We tested whether comprehensive phenotyping validates and further characterises these clusters at diagnosis and whether relevant diabetes-related complications differ among these clusters, during 5-years of follow-up. Methods: Patients with new

Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5+ B cells with low surface immunoglobulins (IG). About 40% of CLL clones utilize quasi-identical B cell receptors, defined as stereotyped BCR. CLL-like stereotyped-IG rearrangements are present in normal B cells as a part of the public IG repertoire. In this study, we collected details on the representation an

BACKGROUND: Capecitabine is an attractive radiosensitizer. In this study acute toxicity and surgical complications were evaluated in patients with locally advanced rectal cancer following total mesorectal excision (TME) after preoperative chemoradiotherapy (CRT) with capecitabine.METHODS: Between 2004 and 2008, consecutive patients with clinical tumour category (cT) 3-4 (with a threatened circumfe

Objective: To determine the diagnostic accuracy of prenatal ultrasound in detecting coarctation of the aorta (CoA). Methods: An individual participant data meta-analysis was performed to report on the strength of association and diagnostic accuracy of different ultrasound signs in detecting CoA prenatally. MEDLINE, EMBASE and CINAHL were searched for studies published between January 2000 and Nove

The Brazilian National Synchrotron Light Laboratory, LNLS, operates a 1.37 GeV electron storage ring with a 120 MeV injector Linac. Commissioning of the storage ring at low energy started on May 1996 and now, an year later, we can store 120 mA at 120 MeV and ramp more than 75 mA to 1.37 GeV. A summary of the latest commissioning results and a description of the present operational performance of t

BACKGROUND: Hormone receptor positivity predicts benefit from endocrine therapy but the knowledge about the long-term survival of patients with different tumor receptor levels is limited. In this study, we describe the 25 years outcome of tamoxifen (TAM) treated patients.PATIENTS AND METHODS: Between 1983 and 1992, a total of 4,610 postmenopausal patients with early-stage breast cancer were random

Background: Mammography screening programmes have been widely implemented across European countries over the past 40 years with the main aim to detect breast cancer earlier and thereby reduce breast cancer mortality. This study aimed to analyse and compare changes over time in breast cancer incidence, by stage at diagnosis, and breast cancer mortality across countries in relation to the timing of

SVENSKANS BESKRIVNING 34 onsdag 22 oktober 2014 09.00 – 12.30 - 13.00 13.00 - 14.00 14.00 - 14.15 14.15 - 14.45 14.45 - 15.15 15.15 - 15.45 15.45 - 16.15 16.15 - 16.45 Ordförande: Björn Melander Ordförande: Ylva Byrman Ordförande: Anna W Gustafsson Ordförande: Andreas Nord Registreringen öppnar utanför Humanisthusets hörsal på Språk- och Litteraturcentrum. Konferensen öppnas av Lynn Åkesson, dekan

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Program231014.pdf - 2026-05-23

bruza C o n c e p t u a l S p a c e s a t W o r k 2 4 - 2 6 M a y 2 0 1 2 h t t p : / / t i n y u r l . c o m / C S a t W o r k - 2 - Conceptual Spaces at Work Lund University, Sweden May 24-26, 2012 http://tinyurl/CSatWork Contents Program p. 3 Abstracts p. 4 Getting to Lund, Food, Cost, etc. p. 11 Map p. 12 Accommodation & Restaurants p. 13 Speakers p. 14 Participants p. 15 Contact p. 16 Sponsor

https://www.fil.lu.se/fileadmin/_migrated/content_uploads/ConceptualSpaceProgram.pdf - 2026-05-23