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Eosinophils—from cradle to grave

Over the past years, eosinophils have become a focus of scientific interest, especially in the context of their recently uncovered functions (e.g. antiviral, anti-inflammatory, regulatory). These versatile cells display both beneficial and detrimental activities under various physiological and pathological conditions. Eosinophils are involved in the pathogenesis of many diseases which can be class

In Situ Detection of Programmed Cell Death Protein 1 and Programmed Death Ligand 1 Interactions as a Functional Predictor for Response to Immune Checkpoint Inhibition in NSCLC

Introduction: Immune checkpoint inhibitors (ICIs) have transformed lung cancer treatment, yet their effectiveness seem restricted to certain patient subsets. Current clinical stratification on the basis of programmed death ligand 1 (PD-L1) expression offers limited predictive value. Given the mechanism of action, directly detecting spatial programmed cell death protein 1 (PD1)–PD-L1 interactions m

How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer

In early breast cancer, a preoperative core-needle biopsy (CNB) is vital to confirm the malignancy of suspected lesions and for assessing the expression of treatment predictive and prognostic biomarkers in the tumor to choose the optimal treatments, emphasizing the importance of obtaining reliable results when biomarker status is assessed on a CNB specimen. This study aims to determine the concord

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

Fusion genes are potent driver mutations in cancer. In this study, we delineate the fusion gene landscape in a consecutive series of 195 paediatric B-cell precursor acute lymphoblastic leukaemia (BCP ALL). Using RNA sequencing, we find in-frame fusion genes in 127 (65%) cases, including 27 novel fusions. We describe a subtype characterized by recurrent IGH-DUX4 or ERG-DUX4 fusions, representing 4%

PHENIX central arm tracking detectors

The PHENIX tracking system consists of Drift Chambers (DC), Pad Chambers (PC) and the Time Expansion Chamber (TEC). PC1/DC and PC2/TEC/PC3 form the inner and outer tracking units, respectively. These units link the track segments that transverse the RICH and extend to the EMCal. The DC measures charged particle trajectories in the r-phi direction to determine P-T of the particles and the invariant

Review of particle physics

This biennial Review summarizes much of Particle Physics Using data from previous editions, plus 2205 new measurements from 667 papers, we list, evaluate, and average measured properties of gauge bosons, leptons, quarks, mesons, and baryons We also summarize searches for hypothetical particles such as Higgs bosons, heavy neutrinos, and supersymmetric particles All the particle properties and searc

GISCOME – Genetics of Ischaemic Stroke Functional Outcome network : A protocol for an international multicentre genetic association study

Introduction: Genome-wide association studies have identified several novel genetic loci associated with stroke risk, but how genetic factors influence stroke outcome is less studied. The Genetics of Ischaemic Stroke Functional outcome network aims at performing genetic studies of stroke outcome. We here describe the study protocol and methods basis of Genetics of Ischaemic Stroke Functional outco

The GALAH survey : A catalogue of carbon-enhanced stars and CEMP candidates

Swan bands-characteristic molecular absorption features of the C2 molecule-are a spectroscopic signature of carbon-enhanced stars. They can also be used to identify carbonenhanced metal-poor (CEMP) stars. The GALAH (GALactic Archaeology with Hermes) is a magnitude-limited survey of stars producing high-resolution, high-signal-to-noise spectra. We used 627 708 GALAH spectra to search for carbon-enh

The centrality of doubting and checking in the network structure of obsessive-compulsive symptom dimensions in youth

Objective. Obsessive-compulsive disorder (OCD) is a heterogeneous condition with well-established symptom dimensions across the lifespan. The objective of the present study was to use network analysis to investigate the internal structure and central features of these dimensions in unselected schoolchildren and in youth with OCD.Method. We estimated the network structure of OCD symptom dimensions

Solvent-Dependent Structural Dynamics in the Ultrafast Photodissociation Reaction of Triiodide Observed with Time-Resolved X-ray Solution Scattering

Resolving the structural dynamics of bond breaking, bond formation, and solvation is required for a deeper understanding of solution-phase chemical reactions. In this work, we investigate the photodissociation of triiodide in four solvents using femtosecond time-resolved X-ray solution scattering following 400 nm photoexcitation. Structural analysis of the scattering data resolves the solvent-depe

Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2)

Aims: The TTM2-trial is a multi-centre randomised clinical trial where targeted temperature management (TTM) at 33 °C will be compared with normothermia and early treatment of fever (≥37.8 °C) after Out-of-Hospital Cardiac Arrest (OHCA). This paper presents the design and rationale of the TTM2-trial follow-up, where information on secondary and exploratory outcomes will be collected. We also prese

Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study

BackgroundThe Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic

High levels of (un)switched memory B cells are associated with better outcome in patients with advanced atherosclerotic disease

Background--Atherosclerosis is an inflammatory lipid disorder and the main underlying pathology of acute ischemic events. Despite a vast amount of data from murine atherosclerosis models, evidence of B-cell involvement in human atherosclerotic disease is limited. We therefore investigated the association of circulating B-cell subtypes with the occurrence of secondary cardiovascular events in advan

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Ovaj članak prezentira teoretski i metodološki model za analizu prepričanih iskustava bivših logoraša koji su kao civili odvedeni u koncentracione logore početkom rata u Bosni i Hercegovini 1990-tih godina. Cilj je analizirati prepričane rituale ratnog nasilja u koncentracionim logorima kao i identifikovati kako se počinioci ratnog nasilja i žrtve simbolično definiraju u pričama. Priče o nasilju u

Effect of Aluminium content on oxidation behavior of arc melted AlxCoCrFeNi (x=0,0.3,0.6,1 mole) high entropy alloys exposed at 1150ºC and comparison with nanocrystalline Al0.6CoCrFeNi high entropy alloy

High entropy alloys (HEA) containing Al and Cr have been observed to manifestimpressive dry air oxidation resistance. But the testing temperature attempted inthe previous works has been restricted up to 1050ºC. In the present work AlxCoCrFeNi HEAs (x=0,0.3,0.6,1 mole) synthesized by arc melting route have beensubjected to rigorous dry air oxidation test up to 1150ºC. The as cast HEAs withx=0 and x

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Populärvetenskaplig sammanfattning av examensarbete i byggnadsmekanik, LTH, Lunds Universitet. Balansering mellan klimatpåverkan och vibroakustik för lätta byggnader Examensarbetare: Philip Carlsson Valet av konstruktionsmaterial i en byggnad har stor betydelse för både vibroakustik (ljud och vibrationer) och miljöpåverkan. Trä ses ofta som ett miljövänligare alternativ gentemot betong som flervån

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/popular_science/Popvet_5253.pdf - 2026-05-28

Bulging of Insulating Glass Units

Bulging of Insulating Glass Units Master’s Dissertation Structural Mechanics MARTIN ANDERSSON and SIMON NILSSON BULGING OF INSULATING GLASS UNITS - Numerical and Experimental Analysis DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--14/5200--SE (1-76) | ISSN 0281-6679 MASTER’S DISSERTATION Supervisor: KENT PERSSON, PhD, Div. of Structural Mechanics, LTH, Lund.

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5200.pdf - 2026-05-28

The social and linguistic construction of time in an Amazonian culture

The social and linguistic construction of time in an Amazonian culture To appear in Luna Filipovič and Kasia M. Jaszczolt (eds.) Space and Time in Languages and Cultures II: Language, Culture, and Cognition. Human Cognitive Processing 37. Amsterdam: John Benjamins. 1 Event-based time intervals in an Amazonian culture. * Vera da Silva Sinha (Federal University of Rondônia) Chris Sinha (Lund Univers

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/SilvaSinha-etal-reprint.pdf - 2026-05-28

Årsberättelse 2022 LTH

Årsberättelse 2022 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET Årsberättelse 2022 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET Årsberättelse 2022 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET FO T O : C A M IL LA L E K E B JE R Förord: Tillsammans utforskar och skapar vi – till nytta för världen 5............................................................................. LTH – åre

https://www.lth.se/fileadmin/lth/omlth/vb/TA-aarsberaettelse2022-LTH.pdf - 2026-05-28

Protokoll HMS-kommitten 2025-06-10

Protokoll HMS-kommitten 2025-06-10 Sida 1 av 3 PROTOKOLL HMS-KOMMITTÉN Diarienummer V2025/1963 Biologicentrum Datum 2025-06-10 Protokoll. Kommittén för Hälsa-, Miljö- och Säkerhet (HMS-K) vid Biologiska institutionen och CEC Närvaro Närvarande ledamöter Jessica Abbott, Prefekt (adjungerad) Henrik Wendel, Ordförande Joakim Nilsson, Administrativ chef, Biologi (adjungerad) Carina Rasmussen Huvudskyd

https://biologi.blogg.lu.se/files/2025/08/HMSProtokoll20250610.pdf - 2026-05-28