Filtyp
Mutations in the PINK1 and PRKN genes are the most frequent genetic cause of early-onset Parkinson disease. The pathogenic p.R275W substitution in PRKN is the most frequent substitution observed in patients, and thus far has been characterized mostly through overexpression models that suggest a possible gain of toxic misfunction. However, its effects under endogenous conditions are largely unknown
A series of orthoborate-based ionic materials of bis(glycolato)borate ([BGB]) and bis(ethylene-1,2-dioxy)borate anions ([BEDB]) coupled with tetrabutylphosphonium ([P4444]) and tetrabutylammonium ([N4444]) cations have been synthesized, and their physicochemical properties are characterized. The ionic materials based on the most popular orthoborate anion, bis(oxalato)borate anion ([BOB]), which co
Pseudo-Random Injections (PRIs) have been used in several applications in symmetric-key cryptography, such as in the idealization of Authenticated Encryption with Associated Data (AEAD) schemes, building robust AEAD, and, recently, in converting a committing AEAD scheme into a succinctly committing AEAD scheme. In Crypto 2024, Bellare and Hoang showed that if an AEAD scheme is already committing
A correct design of controllers must necessarily account for the schedule of the controller task over the processor. Existing design techniques are based on the assumption that there is no delay, or the delay is constant over time. However, in practice, almost all controllers have time-varying delay, hence invalidating this assumption. In this paper, we introduce a period design policy, in which t
Joint wheel-slip and vehicle-motion estimation is considered, based on measurements from wheel encoders, an inertial measurement unit, and a global positioning system (GPS). The proposed strategy effectively employs the Rao-Blackwellized particle-filtering framework using a kinematic model. Key vari- ables in active safety systems, such as longitudinal velocity, roll angle, and wheel slip for all
We present a framework for the solution of control and estimation problems under a signal-to-noise (SNR) ratio constraint. The framework can be used to design optimal linear controllers, based on output feedback, with two degrees of freedom: One part of the controller is placed before the communication channel and represents sensing and encoding operations. The other part represents decoding and i
In neuroscience a number of new techniques have been developed by means of which it has become possible to study the activity of the living human brain. By means of these techniques we are beginning to understand the neurophysiology behind environmental attitudes and preferences. In addition to an introduction to cognitive neuroscience, this invited symposium contains a number of presentations, wh
A general framework for the study of robust synchronisation in large-scale networks is provided. Agents are represented as a common nominal linear time-invariant (LTI) single-input-single-output (SISO) system with simple poles on the imaginary axis, subject to LTI SISO stable multiplicative perturbations. The agents exchange information in order to achieve output-synchronisation, namely steer thei
This paper presents a scheme to construct distributed observers for a system consisting of agents interconnected in a graph structure. The scheme is an iterative procedure to improve the observers with respect to global performance. It is modular in the sense that each agent iterates using only local model information. As a consequence, the complexity of the scheme scales linearly with the size of
In production industry today a lot of engineering time is required to develop and maintain control applications. One part of the control applications are the state machines which typically are written in Grafcet/SFC. Several efforts have been made to extend Grafcet/SFC to achieve more effective and convenient development, e.g. by introducing hierarchical structuring, reusable sub-state machines, a
