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Calcium- and integrin-binding protein 1 (CIB1) is a ubiquitous, multifunctional regulatory protein consisting of four helix-loop-helix EF-hand motifs. Neither EF-I nor EF-II binds divalent metal ions; however, EF-III is a mixed Mg2+/Ca2+-binding site, and EF-IV is a higher-affinity Ca2+-specific site. Through the generation of several CIB1 mutant proteins, we have investigated the importance of th
We report on a newly developed diode-laser spectroscopic system for gas detection in scattering media. Two pigtailed diode lasers are used, operating in a wavelength modulation scheme, to simultaneously detect molecular oxygen at 760 nm and water vapour at 935 nm within the tissue optical window (600 nm to 1.3 μm). Different modulation frequencies are used to distinguish between the two wavelength
Objective. To investigate the perinatal adaptive response of the adrenal blood flow/adrenal fractional moving blood volume (AFMBV) and carotid blood flow (CBF), in sheep fetuses subjected to severe acute intrauterine hypoxia/asphyxia induced by total cord occlusion.Methods. Adrenal blood flow velocity, AFMBV and CBF were measured in 13 exteriorized fetal sheep; eight of them underwent total umbili
The functional relation between receptive fields of climbing fibres projecting to the C1, C3 and Y zones and forelimb movements controlled by nucleus interpositus anterior via the rubrospinal tract were studied in cats decerebrated at the pre-collicular level. Microelectrode tracks were made through the caudal half of nucleus interpositus anterior. This part of the nucleus receives its cerebellar
Perfusion magnetic resonance (MR) imaging is a promising new method for detection of perfusion defects in the diagnosis of pulmonary embolism. In the present study we evaluated the first-pass characteristics of perfusion MR imaging in patients with pneumonia or chronic obstructive pulmonary disease (COPD), frequent differential diagnoses to pulmonary embolism. Dynamic contrast-enhanced MR images o
Objective. Two simulation models were developed to analyze the cost-effectiveness of new treatments that affect the progression of rheumatoid arthritis (RA). Methods. We used data from 2 cohorts of. patients with early RA who had been followed up since disease onset (up to 15 years). In the Swedish study, 183 patients were followed up for a mean of 11.3 years. In the UK study, 916 patients were fo
Study objective: The principle of equity aims to guarantee allocation of healthcare resources on the basis of need. Therefore, people with a low income and persons living alone are expected to have higher healthcare expenditures. Besides these individual characteristics healthcare expenditure may be influenced by country of birth. This study therefore aimed to investigate the role of country of bi
Cytochromes of the c type in the gram-positive bacterium Bacillus subtilis are all membrane anchored, with their heme domains exposed on the outer side of the cytoplasmic membrane. They are distinguished from other cytochromes by having heme covalently attached by two thioether bonds. The cysteinyls in the heme-binding site (CXXCH) in apocytochrome c must be reduced in order for the covalent attac
To test the response of arbuscular mycorrhizal (AM) fungi to a difference in soil pH, the extraradical mycelium of Scutellospora calospora or Glomus intraradices, in association with Plantago lanceolata, was exposed to two different pH treatments, while the root substrate pH was left unchanged. Seedlings of P. lanceolata, colonized by one or other of the fungal symbionts, and nonmycorrhizal contro
Song complexity is often regarded as a sexually selected trait that reflects the overall quality of a male. In many passerine species, old males possess larger song repertoires than younger males. This may be either because individual males improve their performance as they get older (longitudinal increase) or because poor singers have reduced viability and, hence, are underrepresented in old age
The Chiffchaff Phylloscopus collybita is represented in Sweden by two different subspecies; the northern well-established abietinus and the southern recently established collybita which has expanded its range northward during the past two decades. At present, an area approximately 500 km wide separates the two subspecies. In order to document differences between the northern and southern populatio
Popular Abstract in Swedish Hydrofob pervaporation är en lovande teknik för återvinning och anrikning av aromer under milda betingelser men kommersiella tillämpningar av denna process är fortfarande outvecklade. Bättre kunskap om masstransportfenomen i kompositmembran avsedda för pervaporation behövs för utveckling av membran medan processimulering är ett viktigt verktyg för att optimera modulutfoHydrophobic pervaporation has gained a lot of attention as an alternative process for mild aroma recovery, but the real commercial applications of this process are still in their infancies. Better understanding of mass transport phenomena in composite pervaporation membranes is essential from the point of view of membrane manufacturing, while process simulation is an important tool for predicting
Colorectal cancers are globally ranked as the third most common cancer form in terms of incidence and mortality. Diet has long been considered as one of the main factors affecting population outcome regarding development of cancer in the colon. Numerous epidemiological studies have found links between consumption of dietary fibres and milk and reduced risk of cancers including colon cancer. To be
Popular Abstract in Swedish Avsikten med avhandlingen är att ge en bild av Hilding Rosenbergs musikverk "Johannes Uppenbarelse" (1940), för stor orkester, kör och recitation (recitativ), genom att belysa verkets tillkomsthistoria och grundläggande litterära och musikaliska struktur. Som en komposition som från början var avsedd att sändas ut över radion, bestämdes form och innehåll i "Johannes UppThe intention of this dissertation is to provide a portrait of Hilding Rosenberg´s musical work "The Revelation of S:t John" (1940), for a large orchestra, chorus and recitation (recitative), through illuminating the work´s history of origin and basic literary and musical structure. As a composition initially intended for broadcast over the radio, the form and content of "The Revelation of S:t Joh
