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A Monte-Carlo simulation package has been developed to model the response of a detector system for ion identification used in conjunction with ion separators following nuclear reactions. The simulation is written predominantly using the GEANT4 framework but utilises the ion transport code MOCADI for accurate separator and reaction modelling. A novel MOCADI-GEANT4 interface has been developed to ut
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During asthma exacerbations, increased airway inflammation may impair the effects of beta(2)-adrenoceptor (beta(2)AR) agonists. It is unclear whether this impairment is prevented by inhaled glucocorticoids (GCs). We have investigated the relaxation of carbachol-contracted mouse tracheal segments to the beta(2)AR agonists formoterol, terbutaline, and salmeterol. The segments were pre-exposed for 4
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The health impact of dietary replacement of carbohydrates with protein for patients with type 2 diabetes is still debated. This study aimed to investigate the association between dietary substitution of carbohydrates with (animal and plant) protein and 5-year weight change, and all-cause and cardiovascular (CVD) mortality risk in patients with type 2 diabetes.
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The adrenal-derived hormones dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are the most abundant circulating hormones and their levels decline substantially with age. Many of the actions of DHEAS are considered to be mediated through metabolism into androgens and estrogens in peripheral target tissues. The predictive value of serum DHEA and DHEAS for the likelihood of falling is unknown. T
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It has been shown that the exposure to airborne particulate matter is one of the most significant environmental risks people face. Since indoor environment is where people spend the majority of time, in order to protect against this risk, the origin of the particles needs to be understood: do they come from indoor, outdoor sources or both? Further, this question needs to be answered separately for
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Purpose : To evaluate the association between the Society for Vascular Surgery/American Association for Vascular Surgery (SVS/AAVS) anatomical severity grading (ASG) score and operative outcomes in fenestrated endovascular repair (f-EVAR) for juxtarenal aortic aneurysm. Methods : A review was conducted of all patients treated at our clinic with commercially available, custom-made f-EVAR devices be
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Background: The FTO gene harbors the strongest known susceptibility locus for obesity. While many individual studies have suggested that physical activity (PA) may attenuate the effect of FTO on obesity risk, other studies have not been able to confirm this interaction. To confirm or refute unambiguously whether PA attenuates the association of FTO with obesity risk, we meta-analyzed data from 45
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Genetically polymorphic species offer the possibility to study maintenance of genetic variation and the potential role for genetic drift in population divergence. Indirect inference of the selection regimes operating on polymorphic traits can be achieved by comparing population divergence in neutral genetic markers with population divergence in trait frequencies. Such an approach could further be
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The aim of the present animal study was to examine the anti-hypertensive capacity of two probiotic products combining blueberries and the tannase producing probiotic bacteria Lactobacillus plantarum DSM 15313 and to investigate if such an effect is linked to a change in the gut microbiota.
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This study uses an intersectional approach to examine and understand how different social and cultural norms impact women’s agency when choosing infant feeding practice. The study wishes to broaden the debate on how women can succeed with breastfeeding or the infant feeding practice of her choice and decrease harmful premature introduction of solids such as Nestum®. Data was collected via group a
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The aim of this study is to offer as detailed analysis as possible of the Compendium Saxonis, a late medieval abridgement of the famous historical work Gesta Danorum, written towards the end of the XII century by Saxo Grammaticus. Books I–IV and XVI have been used for this purpose. The study contains an introduction, two chapters and a conclusion. In the introduction, scarce information known abou
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The aim of this study was to analyse rural tourism as a tool for poverty reduction, by examining the role of the regulatory framework, including the public and the private sector; and how the participation in rural tourism activities shapes people’s livelihood outcomes in San Pedro de Colalao, Argentina. A case study was carried out, which sought to gain an in-depth understanding about people’s li
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Cruise tourism is the fastest growing segment within the global tourism industry, allowing tourists to visit spectacular coastal destinations all over the world. Due to its pristine fjord landscapes, Norway is a popular cruise destination. Over the past decades, cruise tourism has increased in the country, both in terms of cruise calls and passengers. Yet, cruise tourism is a source of local air p
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Digitalisation has had a profound effect on our society. Much of our daily lives revolve around digital errands that, providing we have the appropriate skills, provide us with innumerous conveniences. Unfortunately for those who do not have such competencies, these normal everyday tasks have become unmanageable and as a result of the McDonaldization of society there are very few places to which th
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In today’s global politics, the Arctic is assuming an increasingly important geoeconomic and geopolitical role among Arctic and non-Arctic states, as the retreating ice cover reveals new economic potentials such as the development of natural resources (Käpylä & Mikkola, 2016). China is among the interested non-Arctic states that aim to increase their influence in Arctic affairs and to get in o
