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Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

Patent misuse and ‘sham’ - Development of new principles under EU competition law

This thesis takes its stance in the AstraZeneca judgment from the General Court and the latest developments in EU competition law and compares these with the equivalent standards of US antitrust law. Focus is on similarities and divergences between the EU application of competition law and the more developed doctrines of Walker Process and Noerr-Pennington in the US. The analysis is made in respec

IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course of disease in a mouse model of intragastric E. coli O157:H7 inoculation. Intraperitoneal administrat

Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are bound

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c

Practical Aspects of Reduced Complexity LDPC Decoding using Forced Convergence

This thesis is an extension to the previous work done at Department of EIT in investigating the complexity reduction of LDPC decoding using the stochastic approximation method to improve the energy efficiency of energy-limited applica- tions, such as in mobile phones. The research carried out in this thesis investigates the complexity and conver- gence results of adaptive performance control algorit

Human Rights Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

Human Rights Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Met

https://rwi.lu.se/tag/human-rights/ - 2026-05-30

Astra and Sirius - tour the Solar system

Astra and Sirius - tour the Solar system | Vattenhallen Science Center Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do no

https://www.vattenhallen.lu.se/vattenhallen-english/the-planetarium/shows-in-english/astra-sirius-and-our-solar-system/ - 2026-05-30

Organizing Critical Infrastructure Services

The case of Waste Management This research project approaches waste management as a combination of critical infrastructure and service industry: a critical infrastructure service. The societal purpose is to show that an effective waste management is a value creating process and the research focus is correspondingly on the organizing of waste management as a critical infrastructure service. The res

https://www.ses.lu.se/organisering-av-kritiska-infrastrukturtjanster-0/organizing-critical-infrastructure-services - 2026-05-31

Soch-infoblad-2016-10-28

Prefekten informerar • Ny medarbetare. Karl Eriksson har antagits till forskarutbildningen och börjar sin doktorandanställning jan 2017. Välkommen! • Skyddsombud. Tina Mattsson är vårt nya skyddsombud. Skyddsombudet har en viktig funktion i institutionens systematiska arbetsmiljöarbete och det faktum att vi är inne i en ombyggnadsprocess och ganska snart måste börja planera för en flytt gör funkti

https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/soch-infoblad-2016-10-28.pdf - 2026-06-01

156911CEC 2024 Fullkost Eng

Fullkostnadskalkyl Full cost for application CEC 2024 Amounts in kkr Project Projectleader University Lund University Faculty NAT Department CEC 156911 Avdelning 0 Påläggsbas Direct salaries and operating costs Do you have co-applicants? (name, dept.) Do you need co-financing of phd-students from CEC? (number, amount (ksek) Which call and funder is the application for? Is the application related t

https://www.cec.lu.se/sites/cec.lu.se/files/2024-02/156911CEC%202024%20fullkost%20eng.xlsx - 2026-06-01

Tentaschema VT 2024 Februari - Augusti 2024 Extern Hemsida 2024-02-09

Institutionen för handelsrätt Uppd: 2024-02-09 Tentamensschema februari 2024 - augusti 2024 Datum Kurskod Kursnamn Tid Lokal Tors 1 feb HARG06 Arbetsrätt II, Dugga 8-10 MA9 Ons 7 feb HARN53 Trade, Investment and Sustainability 8-13 EC2:063 HARN54 Intellectual Property and Trade Ons 28 feb HARA71 Kommersiella avtal och köp 8-13 MA8 HARG15 Compliance och risk i affärslivet HARG03 Kommersiell avtalsr

https://www.ehl.lu.se/sites/ehl.lu.se/files/2024-02/Tentaschema%20VT%202024%20%20februari%20-%20augusti%202024%20extern%20hemsida%202024-02-09.pdf - 2026-06-01

Icoswedenworkshopseptember2014 eng

ICOSpub2014_eng ICOS Sweden is an infrastructure for research on greenhouse gases in northerly  ecosystems. The 2014 workshop focuses on how the carbon and water cycle inter‐ acts in these ecosystems.  The carbon and water cycle is strongly interlinked as water is the essential medi‐ um in which biochemical processes takes place. Water is also the medium that  transports the raw material within th

https://www.cec.lu.se/sites/cec.lu.se/files/icoswedenworkshopseptember2014_eng.pdf - 2026-06-01