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Sustainable access to effective antibiotics is a main rationale for addressing antimicrobial resistance, for calls to enhance antibiotic supply security and for development support to promote health system capacity in low- and middle-income settings. Standard models for valuing pharmaceuticals fail to capture the full value of sustainable access to effective antibiotics. In effect, assessments of
BACKGROUND: School principals face a demanding work situation that puts them at risk for stress-related poor mental health. Ideally, preventive actions should be based on knowledge about the underlying notions that motivate action. However, knowledge about prevention areas and suitable initiatives for school principals is scarce or lacking, leaving key stakeholders without the overview necessary f
Aim: To audit adherence to the Swedish paediatric guidelines for urinary tract infections (UTIs) in infants. Secondary objectives were to compare findings on imaging performed according to the guidelines with imaging without guideline support and to identify predictors of non-adherence. Methods: A prospective multicentre study of infants <1 year treated at paediatric hospitals for their first UTI.
Screening for type 1 diabetes (T1DM) risk in newborns has little negative emotional impact on mothers. In this study, the impact on the mother and the father was evaluated both in the general population and in families with diabetes. All parents with a newborn in Skåne, Sweden, were invited to a screening for T1DM risk in their children (the Diabetes Prediction in Skåne (DiPiS)). Blood was obtaine
Nanowires are structures with features on the nanoscale, and it is therefore essential to study their properties on that scale. We present optical data from a variety of nanowire-based structures using cathodoluminescence imaging and spectroscopy. One important feature of nanowires is the stacking sequence of the crystal, either zincblede, wurtzite or a mix of the two. We show that this has an imp
After almost two years living in Malmö, I discovered Nyhamnen by reading about the municipality plans for the area in a local newspaper. The mere realization that I was not aware of such a large area, only five minutes walking from the central station was both surprising and challenging. Since then, the aim of this thesis has been to develop an urban proposal that even though it is an academic exe
In other hazardous complex socio-technical systems in society, e.g. nuclear power and aviation, systems-theoretical assumptions are considered a promising way to better understand and manage safety. In this paper, two fundamental approaches to road safety were assessed in the light of a systems theory approach. One approach, is based on a premise where individual road-users are solely responsible
Abstract in UndeterminedThe recent MPEG Reconfigurable Media Coding (RMC) standard aims at defining media processing specifications (e.g. video codecs) in a form that abstracts from the implementation platform, but at the same time is an appropriate starting point for implementation on specific targets. To this end, the RMC framework has standardized both an asynchronous dataflow model of computat
We have developed a method to estimate free energies of reactions in proteins, called QM/MM-PBSA. It estimates the internal energy of the reactive site by quantum mechanical (QM) calculations, whereas bonded, electrostatic, and van der Waals interactions with the surrounding protein are calculated at the molecular mechanics (MM) level. The electrostatic part of the solvation energy of the reactant
Jobbgarantin för ungdomar (UGA) står i linje med en utvecklingstendens på den svenska arbetsmarknadspolitiken som i allt större utsträckning satsar på en intensifierad förmedling, istället för insatser som syftar till att höja ungdomars kompetens. Detta står i kontrast mot samhällvetenskapliga koncept om arbetsmarknadens utveckling, som även kan konstateras i Sverige: en ökad tjänsteorientering oc
One of the main contributors in the immune system are T cells. The exact molecular mechanisms behind T cell activation are not yet fully understood but it starts through the contact between the T cell and an infected cell. In order to study such interaction, supported lipid bilayers (SLBs) are used to mimic cell membranes and to reduce its complexity but still retaining the fundamental property of
The topic of the thesis is re-initialization of multistep methods for the solution of ordinary differential equations, in which there are frequent discontinuities in first or higher derivatives. There are self-starting algorithms to start or restart a multistep method. It is normally started by first using a one-step method and then increasing the order successively until the working order is reac
Under 1990-talet genomfördes flera omdiskuterade humanitära interventioner. De som var kritiska hävdade att interventionerna var en oacceptabel kränkning av suveränitetsprincipen. Förespråkare menade att respekten för mänskliga rättigheter var ett viktigare intresse att skydda. 2001 släpptes en rapport som fick stor betydelse för den globala utvecklingen på området. I rapporten lanserades koncepteDuring the 1990s there were several controversial humanitarian interventions. Critics argued that the interventions were an unacceptable violation of the principle of sovereignty. Proponents argued that the respect for human rights was an interest of more importance. In 2001 a report that was of great importance for the continued global development was released. The report launched the concept of
Empiriskt undersöka principal-agent-teorins relevans i komplexa och kunskapsintensiva ”business to business” relationer. Med en induktiv ansats genomförs en kvalitativ fallstudie. Insamlad data har analyserats med hjälp av ”pattern matching”, med potentiella förklaringsvariabler på förhand identifierade genom en marknadsanalys, omfattande litteraturstudie och en pilotintervju, vilket har mynnat ut
With the increasing portfolio of options when looking for new mobile apps and web tools their is a need to excel. One of the possible solutions is to capture and hold on to the users by introducing gamification that motivates the user and gives them the opportunity to feel more engaged with a product. This master thesis examines a possible gamification design for the software solution KLAR. KLAR c
Recycling has become increasingly relevant to solve environmental problems related to the enormous amount of plastic waste. Recycling plastic has many environmental benefits, but it is challenging to find applications where recycled plastic can provide the same functionality as virgin plastic. This thesis highlights the challenges of using recycled High-density polyethylene (HDPE) in pipe applicat
