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Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest
BACKGROUND: Definition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with severe hypoxia-ischaemia and reperfusion. It may further explore intervention effects for new mechanistic insights, identify candidate prognostic protein biomarkers and potential therapeutic targets. This pilot study aimed to investigate serum proteome p
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"Den passiva majoriteten" – en nyckel till varaktig förändring
Kvinnan från Barum – från äldre stenåldern : En forskningshistorik samt därtill några ställningstaganden och tillrättalägganden, kritiska anmärkningar och slutsatser.
Electrocatalytic proton reduction by thiolate-capped triiron clusters [Fe3(CO)9(μ3-SR)(μ-H)] (R = iPr, tBu)
Jaco Zuijderduijn
Universitetslektor Kontaktinformation E-post: jaco [dot] zuijderduijn [at] ekh [dot] lu [dot] seOrganisation Ekonomisk-historiska institutionen Besöksadress: Scheelevägen 15 B, Lund Rumsnummer: Alfa1:2109 Hämtställe: 10 WebbplatsJaco Zuijderduijns profil i Lunds universitets forskningsportalAndra roller Universitetslektor Finanshistoria, banker och försäkringar Universitetslektor Tillväxt, teknolo
https://www.ehl.lu.se/jaco-zuijderduijn - 2026-05-06
A comparison of different orthogonal techniques for the investigation of the conformational stability of NIST mAb in liquid formulations
Antikroppar har ett brett användningsområde med stor potential men det är svårt att skapa stabila lösningar. Den strukturella stabiliteten är en viktig faktor när man väljer läkemedelskandidater, och i de tidiga utvecklingsstadierna görs prediktiva undersökningar för att ta reda på varje kandidats stabilitet och utvecklings-potential. Därmed är det av största intresse att utvärdera hur antikropparA great challenge during early development of medicinal antibodies is to determine the stability of the candidates. This is required to be able to select the candidates with the greatest developability. The stability of the candidates can be estimated using different orthogonal techniques and the aim of this investigation was thus to use orthogonal techniques for the investigation of conformationa
Effects of chronic citalopram treatment on central and peripheral spontaneous open-field behaviours in rats
The spontaneous open-field behavioural effects of 10 days of chronic treatment with two clinical doses (10 and 20 mg/kg daily) and one high/toxic dose (100 mg/kg daily) of the selective serotonin reuptake inhibitor citalopram (delivered subcutaneously by implanted osmotic pumps) were examined in rats. Central and peripheral arena locomotor and rearing activities were recorded simultaneously, and t
Circular business models in Japan : Analysis of circular business transformation through an institutional approach
The circular economy is becoming a globalised phenomenon, but the regional emergence of circular business models differs significantly. By adopting a circular business institutionalisation perspective which bridges theory on institutional work and “ecologies of business models” we study the emergence of circular business models in Japan, a region with recent circular policy and business commitment
Dissecting Lewis score under the light of fecal calprotectin; an analysis of correlation of score components with calprotectin levels in capsule endoscopy.
Preface
Selection on the joint actions of pairs leads to divergent adaptation and coadaptation of care-giving parents during pre-hatching care
The joint actions of animals in partnerships or social groups evolve under both natural selection from the wider environment and social selection imposed by other members of the pair or group. We used experimental evolution to investigate how jointly expressed actions evolve upon exposure to a new environmental challenge. Our work focused on the evolution of carrion nest preparation by pairs of bu
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Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q
Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i
