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Objective. To compare the effect of intraarticular injections of hyaluronan and placebo (vehicle, saline) in patients with knee pain on exertion and with joint cartilage abnormalities. Methods. Fifty-two patients with arthroscopically verified deep cartilage fissures and villus-like flakes in the symptomatic knee were randomly assigned to receive intraarticular injections of 2.5 ml of either hyalu
The purpose of this work is to present results from an ongoing study on how the presence of surfaces influences the buckling properties of nanowires. This study is performed using molecular statics simulations where the interatomic interaction is modelled using an embedded atom potential (EAM) fitted to gold properties. The considered nanowires have rectangular cross sections with cross sectional
Alkyl glycosides were synthesised from starch and alcohols using Aspergillus oryzae a-amylase as catalyst. In the degradation of starch by a-amylase, the alcohols competed with water as glycosyl acceptors. In the reaction with methanol, methyl maltoside and methyl maltotrioside were the main alcoholysis products. Conversion of 45 g/1 starch in 30% methanol resulted in a product mixture containing
UV-B treatment of thylakoid membranes or fractions derived from them accelerates the first rise (Fo---Fi phase) of variable fluorescence and slows down the second (Fi---Fm) rise. This can be observed for all membrane fractions but to different extents. The grana fraction is affected more by the UV-B treatment than are the intact thylakoids and the stroma lamella fraction. An exogenous electron acc
A control system for pneumatic variable valve actuation has been designed, implemented and tested in a single cylinder test engine with valve actuators provided by Cargine Engineering AB. The design goal for the valve control system was to achieve valve lifts between 2 and 12 mm over an engine speed interval of 300 to 2500 rpm. The control system was developed using LabView and implemented on the
The ATP- and UTP-sensitive P2Y2 receptor which mediates both contractile and mitogenic effects has recently been shown to be upregulated in the synthetic phenotype of the vascular smooth muscle cell (VSMC). Using a competitive RT-PCR we demonstrate that the P2Y2 receptor mRNA is increased by fetal calf serum and other growth factors in a MAPKK-dependent way. This was confirmed at the functional le
A technology was developed to embed nm-sized metallic features in close vicinity to semiconductor heterostructures, which allows a direct integration of resonant tunneling diodes (RTD) inside the channel of permeable base transistor. A AlGaAs/InGaAs based RTD was grown by molecular beam epitaxy (MBE), with peak current density either 70 or 120 kA/cm2. A fundamental oscillation frequency
In this study stool samples from dyspeptic patients and healthy subjects were used for detection of specific Helicobacter pylori antigens and DNA by immunoenzymatic test (PPHpSA) and semi-nested PCR (ureA-PCR), respectively. The H. pylori status was estimated by invasive endoscopy-based rapid urease test and histology or noninvasive urea breath test (UBT), and by serology (ELISA, Western blot). Th
Calculated absorbed dose distributions from tangential irradiation of the breast have been compared with TLD measurements in a anthropomorfic body-shaped phantom which has gone through all phases of the radiation treatment planning cycle, including mapping of electron densities with a CT scanner, simulation of beam set-up and several treatments with an accelerator. The absorbed doses, measured in
Downlink beamforming in Massive MIMO either relies on uplink pilot measurements--exploiting reciprocity and time-division duplexing (TDD) operation, or on the use of a predetermined grid of beams with user equipments reporting their preferred beams, mostly in frequency-division duplexing (FDD) operation. Massive MIMO in its originally conceived form uses the first strategy, with uplink pilots, whe
A search for events containing an isolated electron or muon and missing trans verse momentum produced in e(+/-)p collisions is performed with the H1 and ZEUS detectors at HERA. The data were taken in the period 1994-2007 and correspond to an integrated luminosity of 0.98 fb(-1). The observed event yields are in good overall agreement with the Standard Model prediction, which is dominated by single
The accuracy of auxiliary basis sets derived from Cholesky decomposition of two-electron integrals is assessed for excitation energies calculated at the state-average complete active space self-consistent field (CASSCF) and multiconfigurational second order perturbation theory (CASPT2) levels of theory using segmented as well as generally contracted atomic orbital basis sets. Based on 196 valence
Current research on enzyme based electrochemical biosensors deals essentially with the same target analytes as was at focus in the early days of biosensor research, that is those within the clinical/medical, food/agriculture, and environmental fields [1•–13]. However, there has been substantial progress through the years and progress continues, as resumed in Figure 1A. One of the major differences
