Filtyp
The dissertation can be divided into two parts, the first of which is a detailed analysis of three excavations concerning Mellanbyn in southern Malmö. In the second part I study the more general development of society, relating Mellanbyn to the surrounding area as well as to the region as a whole during Late Bronze Age and the Early Iron Age. The aim can be summed up as being to study the developm
Popular Abstract in Swedish I dag används cellhämmande medel, cytostatika, ofta i kombination med andra metoder för behandling av vissa typer av cancer. Cytostatika kan bota t.ex. leukemi, testikel- och lymfkörtelcancer, eller lindra symtomen och förlänga livet vid t.ex. småcellig lungcancer. En grupp av cytostatika utgörs av metallkomplex där metallen är platina (Pt). Upptäckten av en sådan förenThe kinetics and mechanism for interactions of the anticancer active platinum(II) complexes cis-[PtCl2(NH3)2)], cis-[PtCl2(NH3)(c-C6H11NH2)], and trans-[PtCl2-(NH3)(quinoline)] with DNA have been studied using a combination of HPLC, circular dichroism (CD), UV/vis spectroscopy, and differential scanning calorimetry (DSC). Reactions of the monoaqua forms (charge = +1) of these complexes with single
Popular Abstract in English All living things somehow communicate with each other. Cell-to-cell communication, or signalling, occurs on the molecular level, regulating the body’s activities and coordinating various cell actions and is thereby valuable for realizing cell as well as system functions. Errors in the cellular transferred information may induce diseases such as cancer and autoimmune disGlypicans are multifunctional cell surface heparan sulphate proteoglycans co-regulating numerous signalling pathways, and are thereby involved in the control of cellular division, differentiation, and morphogenesis. The heparan sulphate (HS) chains are responsible for many of those biological functions; nevertheless recent studies suggest functional roles for the glypican core proteins in mediatin
Chancroid caused by Haemophilus ducreyi, has been described as a significantly predisposing factor of HIV heterosexual transmission in an endemic region of both diseases. Antibiotic resistances are extensively found in H. ducreyi and many of the resistances are due to the presence of resistance plasmids. A high tendency of drug resistances has commonly been found among isolates derived in Thailan
Popular Abstract in Swedish Evolusjon og energikonservering i en katalysator i cellens kraftverk Alle levende organismer må omforme energien i mat eller sollys til en form som cellen kan bruke som energi. Energien brukes både til prosesser som bryter ned og bygger opp komponenter i cellen. Den brukes også til prosesser som muskelsammentrekninger, celledelinger og bevegelser. Uansett hva slags cel
My thesis is part of an overall environmental program evaluating the environmental and human health stress in areas of Nicaragua affected by anthropogenic emission of metals and man-made organic substances. I examine the fluvial transport of mercury contextually associated with the extent of the contamination and the observed human and environmental stress in a gold mining area. Field measurements
Around 70,000 osteoporosis-related fractures occur in Sweden annually and approximately half of the women in western world will sustain a fragility fracture after the age of 50 years. Fracture preventive efforts require the identification of individuals who are at high risk. Biochemical markers of bone turnover (BTMs) have shown some degree of fracture predictability. There is also a correlation b
Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. Since majority of the mitochondrial genes are encoded by the nuclear genome, a tightly regulated and coordinated nuclear-mitochond
This dissertation examines how young people with Kurdish backgrounds form their identity in Sweden with regards to processes of inclusion and exclusion. It also sheds light on the ways these young people deal with ethnic discrimination and racism. Further, the study outlines the importance of these social processes for the discipline of social work and the ways social workers can work with disadva
We have measured the uptake capacity of nitrogen (N) and potassium (K) from different soil depths by injecting N-15 and caesium (Cs; as an analogue to K) at 5 and 50 cm soil depth and analysing the recovery of these markers in foliage and buds. The study was performed in monocultures of 40-year-old pedunculate oak (Quercus robur), European beech (Fagus sylvatica) and Norway spruce (Picea abies (L.
The quinoline-3-carboxamides (Q compounds) are a family of small molecules that ameliorate various types of murine inflammatory autoimmune disease. One such compound has also demonstrated anti-tumor effects in murine tumor models. Several Q compounds have reached clinical trials and one compound, laquinimod, is currently in phase III clinical trial for relapsing-remitting multiple sclerosis. The Q
BACKGROUND: Postmenopausal hormone therapy (HRT) and oral contraceptive (OC) use have in several studies been reported to be associated with a decreased colorectal cancer (CRC) risk. However, data on the association between HRT and OC and risk of different clinicopathological and molecular subsets of CRC are lacking. The aim of this molecular pathological epidemiology study was therefore to evalua
BACKGROUND: Gonadotropin-releasing hormone (GnRH) antagonists have been reported to have beneficial effects on lower urinary tract symptoms in patients with benign prostatic hyperplasia. OBJECTIVE: Our aim was to investigate the effects of ganirelix, a GnRH receptor antagonist, on bladder function and detrusor overactivity (DO) in female rats. DESIGN, SETTING, AND PARTICIPANTS: Female Sprague-Dawl
The objectives of this thesis are to find a common ground for business and environmental interests and to evaluate the potential of Environmental Management Systems (EMSs) as transition tools to lead towards a greener economic paradigm. For these purposes it was assessed, which implications EMSs have for the competitiveness of small and medium sized enterprises (SMEs) within the first three years
Populärvetenskaplig sammanfattning Vi lever idag i ett informationssamhälle och delar av denna information är geografisk. Denna geografiska information kan användas för att skapa kartor efter egna önskemål och för specifika användningsområden. Genom att ansluta till en webbsida som tillhandahåller visningstjänster av kartor kan en användare välja vilken information som ska vara med i en karta och We live in an information intensive society and geographic data are part of this information. These geographic data are used by private persons to plan holiday trips or to find the way to business meetings. Companies utilize geographic data in fields such as forestry, construction work, and tourism. Local municipalities require geographic data for planning purposes, and in the academic world much
En vegetationskarta och en digital höjdmodell har gjorts över ett 54 km2 stort område beläget på Svalbards västkust, vid Isfjorden. Vegetationskartan är baserad på flygbilder och en undersökning gjord i fält under juli månad 1994. Systemet som användes vid klassificeringen av de olika vegetationstyperna är utarbetad av Elven et al. (1990) för en liknande studie i Gipsdalen på Svalbard. Vår vegetatA vegetation map and a Digital Elevation Model has been generated over a 54 km2 area situated at the western coast of Svalbard, at the Isfjorden fiord. The map is based on aerial photographs and a field survey made during the summer of 1994. The classification system used is described by Elven et alia (1990), for a similar study in Gipsdalen in the inner part of Isfjorden. The classification of th
Med den globala uppvärmningen förutspås klimatet i arktiska och subarktiska miljöer förändras påtagligt. Enligt IPCCs senaste rapport kan både temperatur och nederbörd öka dubbelt så mycket som det globala genomsnittet, och störst ökning väntas under vinterhalvåret. Många känsliga ekosystem och miljöer kommer med stor sannolikhet att påverkas redan vid små förändringar. Ett exempel på sådana miljöThe on-going global warming is projected to have large impacts on the arctic and subarctic environment. Especially vulnerable are ecosystems with narrow climatic envelopes and with small possibilities of adaptation. An example of this is the palsa mires, subarctic mire complexes with patches of permafrost. Palsas are peat mounds with a frozen core, formed by the expansion and upheaval of the segre
