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Assisterad befruktning är en möjlighet som erbjuds par och ensamstående för att komma tillrätta med ofrivillig barnlöshet. Assisterad befruktning kan genomföras antingen genom insemination eller genom befruktning utanför kroppen. År 2005 fick samkönade par tillgång till assisterad befruktning inom svensk sjukvård på samma villkor som olikkönade par. Det är dock fortfarande ett alternativ att utförAssisted reproduction is an opportunity that is offered to couples and singles to deal with infertility. Assisted reproduction can be carried out either through insemination or through in vitro fertilization. In 2005, same-sex couples got legal access to assisted reproduction within Swedish healthcare on the same terms as opposite-sex couples. However, it is still an option to get the treatment ou

Objective To compare, in young active adults with an acute anterior cruciate ligament (ACL) tear, the mid-term (five year) patient reported and radiographic outcomes between those treated with rehabilitation plus early ACL reconstruction and those treated with rehabilitation and optional delayed ACL reconstruction. Design Extended follow-up of prospective randomised controlled trial. Setting Ortho

BACKGROUND: Despite marked improvement in therapy and monitoring of patients with insulin-dependent (type 1) diabetes, diabetic nephropathy remains a serious complication, with subsequent end-stage renal disease in about 20% of cases. OBJECTIVE: To investigate in young patients with type 1 diabetes whether urine α-Glutathione S-transferase to creatinine ratio (α-GST:crea) relates to markers of s

BACKGROUND & AIMS: Little is known about recurrence of pancreatitis after an initial episode, and little is known about how the disease progresses or what factors affect progression. We performed a population-based study of patients with acute pancreatitis (AP) to determine their outcomes and associated factors. METHODS: We performed a retrospective study of patients with first-time AP from 20

Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone and estradiol. SHBG has been associated with chronic diseases including type 2 diabetes (T2D) and with hormone-sensitive cancers such as breast and prostate cancer. We performed a genome-wide association study (GWAS) meta-analysis of 21,791 i

Popular Abstract in Swedish Spridningshamstring är en form av matlagring som används av många djur för att t.ex. överleva en lång svår vinter då det finns mycket lite mat i naturen. I Sverige är talltitan en av de i särklass främsta spridningshamstrarna och den brukar lagra tiotusentals frön inför varje vinter. Ett flertal andra mesfåglar, nötskrikor och nötkråkor har samma vanor. Det som skiljer Food hoarding is a widespread behavior among a large number of animals, and it exists in several different varieties, all of them used by the animals as a method of having a steady supply of food during periods of low food abundance such as the winter. This thesis concentrates mainly on two aspects of scatter food hoarding behavior, using small birds as study and model animals. Scatter hoarding is

During the past few years, extensive effort has been devoted to developing quality systems as an integral part of the process in the construction sector. The construction process is complex, involving many different actors with different interests. The demand for quality assurance comes primarily from central authorities via the client, but quality systems should be applied throughout the whole ch

Popular Abstract in Swedish Det övergripande syftet med denna avhandling var att lyfta fram barns kreativitet och barnens egna perspektiv på kreativitet, som en kontrast till studier som undersöker begreppet ur ett vuxenperspektiv och utifrån en akademisk definition. Avhandlingen består av två kvasi-experimentella studier och en intervju studie. I Studie I undersöktes associationer mellan kreativiThe main aim of the present investigation was to highlight middle childhood creativity, and the children’s perspective on creativity, in contrast to many, if not most, studies that investigate creativity from an adult perspective and a scholarly definition. This dissertation consists of two quasi-experimental studies, and one interview study. Study I investigated if, and how, state anxiety, brough

Rapporten redovisar data om hur SI-verksamheten vid fem civilingenjörsprogram vid LTH inverkar på studieresultaten under det första läsåret samt på resultaten i en inledande matematikkurs till vilken SI-verksamheten är knuten. SI står för SamverkansInlärning och är en metod där en äldre student ”coachar” en grupp med nya studenter till att diskutera och lösa problem i ett ämne. Metoden syftar vid

Popular Abstract in Swedish År 2011 är det exakt 20 år sedan lärarkåren kommunaliserades. Reformen ger fortfarande upphov till diskussioner, inte minst från liberalt håll diskuteras idag lärarprofessionens status och vilka konsekvenser kommunaliseringen har medfört. I Professionens problematik analyseras motiven bakom kommunaliseringen. Historikern Johanna Ringarp visar att reformen var ett led i On 8 December 1989, the Swedish Parliament resolved that the state regulation of teaching positions would be terminated beginning on 1 January 1991. The parliament’s decision came on after fierce debates that took place in both teacher staff rooms and in public in 1989. Almost 20 years later, the reform still gives rise to controversy, and current political debates also touch on the possibility of

OBJECTIVE: To study intra-aneurysm sac pressure and subsequent abdominal aortic aneurysm (AAA) diameter changes in patients without endoleaks that remain unchanged in AAA diameter more than 1 year after endovascular aneurysm repair (EVAR). METHODS: A total of 23 patients underwent direct intra-aneurysm sac pressure (DISP) measurements 16 months (IQR: 14-35 months) after EVAR. Tip-pressure sensors

Background: Cardiovascular Magnetic Resonance (CMR) enables non-invasive quantification of cardiac output (CO) and thereby cardiac index (CI, CO indexed to body surface area). The aim of this study was to establish if CI decreases with age and compare the values to CI for athletes and for patients with congestive heart failure (CHF). Methods: CI was measured in 144 healthy volunteers (39 +/- 16 ye

Background: Several attempts to increase the locoregional control in locally advanced lung cancer including concurrent chemotherapy, accelerated fractionation and dose escalation have been made during the last years. As the EGFR directed antibody cetuximab has shown activity concurrent with radiotherapy in squamous cell carcinoma of the head and neck, as well as in stage IV NSCLC combined with che

Background: Ghrelin derives from endocrine cells (A-like cells) in the stomach (mainly the oxyntic mucosa). Its concentration in the circulation increases during fasting and decreases upon re-feeding. This has fostered the notion that the absence of food in the upper gastrointestinal (GI) tract stimulates the secretion of ghrelin. The purpose of the present study was to determine the concentration

BACKGROUND CONTEXT: Several studies report a favorable short-term outcome after nonoperatively treated two-column thoracic or lumbar burst fractures in patients without neurological deficits. Few reports have described the long-term clinical and radiological outcome after these fractures, and none have, to our knowledge, specifically evaluated the long-term outcome of the discs adjacent to the fra

Importance: Although tramadol is increasingly used to manage chronic noncancer pain, few safety studies have compared it with other opioids. Objective: To assess the associations of tramadol, compared with codeine, with mortality and other adverse clinical outcomes as used in outpatient settings. Design, Setting, and Participants: Retrospective, population-based, propensity score-matched cohort st

Importance: Supplementing preterm infants with long-chain polyunsaturated fatty acids (LC-PUFA) has been inconsistent in reducing the severity and incidence of retinopathy of prematurity (ROP). Furthermore, few studies have measured the long-term serum lipid levels after supplementation. Objective: To assess whether ROP severity is associated with serum levels of LC-PUFA, especially docosahexaenoi

Aims: Because evidence regarding risk stratification predicting prognosis of patients with heart failure (HF) decompensation attended in primary care is lacking, we developed and externally validated a model to forecast death/hospitalization during the first 30 days after an episode of decompensation. The predictive model is based on variables easily obtained in primary care settings. Methods and

Background: An anterior cruciate ligament (ACL) rupture results in an increased risk of developing knee osteoarthritis (OA) at an early age. Before clinical signs become apparent, the OA process has already been initiated. Therefore, it is important to look at the cascade of changes, such as the activity of cytokines and proteases, which might be associated with the later development of OA. Purpos