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MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

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Michelle et Monique sont deux filles qui aiment de voyager. Elles ont été au Danemark, en Algérie, aux Étatés-Unis, en Angleterre et en Espagne. Mais cette temps elles voulent de visiter une payé éxotique. Michelle et Monique ´ont décidé de voyager en Italie. Michelle: En Italie il fait chaud et on peut bagner et bronzer. Monique: Précisément! Et la norritûre et super. Michelle: J'aime la langue b

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_c/Chlo%C3%A9.txt - 2026-05-25

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Des de principis del segle xxi, una nova fornada d’estudis sobre la història del cooperativisme s’ha interessat per la influència d’aquest moviment d’emancipació en la configuració dels barris populars. Des d’una perspectiva urbana i microhistò- rica, la recerca sobre cooperatives i cooperativistes ha nodrit l’anàlisi de les relacions entre cooperativisme, obrerisme i associacionisme popular

On-Conditionalism : On the verge of a new metaethical theory

This paper explores a novel metaethical theory according to which value judgments express conditional beliefs held by those who make them. Each value judgment expresses the belief that something is the case on condition that something else is the case. The paper aims to reach a better understanding of this view and to highlight some of the challenges that lie ahead. The most pressing of these revo

Victoria Martinez

Researcher Contact details Email: victoria [dot] martinez [at] hist [dot] lu [dot] seOrganisation History Service point: 30 WebpageVictoria Martinez profile in Lund University research portalOther affiliations Profile area member LU Profile Area: Human rights Publications Displaying of publications. Sorted by year, then title. Filter by type AllBook chapterConference paperDissertationEditor for a

https://www.humanrights.lu.se/victoria-martinez - 2026-05-25

Prospective observational study of tofacitinib in ulcerative colitis - analysis of clinical data, fatigue and health-related quality of life during the induction phase

BACKGROUND: Tofacitinib is a Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Prospective real-world data are scarce.OBJECTIVES: To collect data on clinical outcomes, including health-related quality of life (HRQoL) and fatigue during treatment with tofacitinib.DESIGN: This is a prospective observational multicentre study in Sweden. In this analysis, outcomes at weeks 2, 8 and

Vulnerability versus resilience to prenatal stress in male and female rats; Implications from gene expression profiles in the hippocampus and frontal cortex

Adverse life events during pregnancy may impact upon the developing fetus, predisposing prenatally stressed offspring to the development of psychopathology. In the present study, we examined the effects of prenatal restraint stress (PS) on anxiety- and depression-related behavior in both male and female adult Sprague-Dawley rats. In addition, gene expression profiles within the hippocampus and fro

Germline heterozygous variants in genes associated with familial hemophagocytic lymphohistiocytosis as a cause of increased bleeding

Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes UNC13D, STX11 and STXBP2 have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients heterozygou

Coordination Complexes of Molybdenum with 3,6-Di-tert-butylcatechol. Addition Products of DMSO, Pyridine N-oxide, and Triphenylarsine Oxide to the Putative [MoVIO(3,6-DBCat)2] Monomer and Self-Assembly of the Chiral [{MoVIO(3,6-DBCat)2}4] Square

Molybdenum complexes of 3,6-di-tert-butylcatechol have been prepared from the reaction between [Mo(CO)6] and 3,6-di-tert-butyl-1,2-benzoquinone. A putative "[MoO(3,6-DBCat)2]" monomer is assumed to form initially by reaction with trace quantities of oxygen. Condensation of the reaction mixture leads to the formation of oligomeric products, including the [{MoO(3,6-DBCat)2}4] chiral square isolated

Sharing cities sweden - introduction

PowerPoint Presentation Sharing Cities Sweden A national program for the sharing economy in cities Kes McCormick, Program Coordinator Schedule  13.00 – 13.20 – Introduction to Sharing Cities Sweden  13.20 – 14.00 – Keynote from the Sharing Cities Alliance (Harmen van Sprang)  14.00 – 14.40 – Presentation by Gothenburg and Malmö Test-beds  14.40 – 15.10 – Fika  15.10 – 15.50 – Presentation by

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/sharing_cities_sweden_-_introduction.pdf - 2026-05-25