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In chlorophyll biosynthesis, insertion of Mg2+ into protoporphyrin IX is catalysed in an ATP-dependent reaction by a three-subunit (BchI, BchD and BchH) enzyme magnesium chelatase. In this work we present the three-dimensional structure of the ATP-binding subunit BchI. The structure has been solved by the multiple wavelength anomalous dispersion method and refined at 2.1 A resolution to the crysta

Popular Abstract in Swedish Hjärtats skrifter är en undersökning av brevet som kommunikationsform under 1700-talet. Brevkulturen i 1700-talets Tyskland betraktas som ett av startskotten för vad som brukar kallas den moderna tiden. I denna studie granskas brevkulturens funktion och betydelse för det epistemiska skifte som äger rum under senare hälften av 1700-talet. Undersökningens utgångspunkt ärThis dissertation examines the correspondence of the 18th-century German authors Anna Louisa Karsch and Johann Wilhelm Ludwig Gleim. The main emphasis of the present study is to demonstrate how readings of Karsch's and Gleim's correspondence shed light on epistolary culture. Particular attention is paid to the notion of epistolary culture as a relatively unrestrained ?experimental setting? for bou

An ability to interact with plasminogen or plasmin could provide micro-organisms with a mechanism for invasion. Thus, group A, C and G streptococci secrete streptokinase which binds and activates plasminogen. Some streptococci also express surface structures which bind plasminogen without causing its activation. Plasminogen-binding surface proteins were extracted from one group C and one group G s

Background: Little is known regarding vitamin D deficiency (VDD) in African populations and in tuberculosis (TB) patients. VDD has been shown to be associated with TB. Objective: We aimed to compare the degree of vitamin D insufficiency (VDI) and VDD in TB patients and healthy adult controls in a West African population. Design: An unmatched case-control study was performed at a Demographic Survei

Context. Manganese is an iron-peak element and although the nucleosynthesis path that leads to its formation is fairly well understood, it remains unclear which objects, SN II and/or SN Ia, that contribute the majority of Mn to the interstellar medium. It also remains unclear to which extent the supernovae Mn yields depend on the metallicity of the progenitor star or not. Aims. By using a well stu

Popular Abstract in Swedish I denna avhandling studeras förändringar i individers religiositet i samband med migration och vad som orsakar sådana förändringar. Det huvudsakliga materialet för studien består av intervjuer med sverige-chilenare boende i Malmö-Lundområdet, vilka berättat om vad som skett med deras religiositet efter ankomsten till Sverige. I arbetet ingår även en brevenkät till sveriThe purpose of this study is to examine changes related to migration in the religiosity of individuals and what lies behind such changes. The study is foremost based on interviews with 23 Swedish-Chileans who have lived in Sweden for an extended period of time and who were adults when they immigrated to Sweden. The interviews are thematic life stories. Each one of the individuals narrates his or h

The Broad-billed Sandpiper Limicola f. falcinellus is a little studied European wader species with unfavourable conservation status. We describe the migration of the Broad-billed Sandpiper at Ottenby, southeast Sweden, from 1950-2000 using data from ringing activities and field observations. Numbers of ringed and observed Broad-billed Sandpipers varied considerably between years. There was no tren

Exempel från 1600-talet på förändringar av mi'kmaqs traditioner visar att mötet med den europeiska kulturen inte var konfliktfritt och mötte motstånd från mi'kmaq. Beskrivningarna om missionens snabba framgång ger inte en helt rättvisande bild. Det var missionärerna som skrev historien och de ville också framstå i en fördelaktig dager inför sina överordnade. För de mi'kmaq som samlades kring missi

Popular Abstract in Swedish Trots att kroppen skyddas av ett hudlager på utsidan och av epitelceller i kroppens inre organ utsätts vi hela tiden för infektioner. När en vävnad blir infekterad börjar cellerna utsöndra inflammatoriska mediatorer som bland annat orsakar svullnad och rodnad. En inflammation kan också orsakas av till exempel slag eller brännskador. De inflammatoriska mediatorerna signaThis thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. Immunohistochemistry revealed that E-selectin was preferentially expressed in ve

This thesis presents development of new analytical methods using antibodies and molecularly imprinted polymers (MIPs) in binding assays: 1) The high specificity of antibodies and the wide variety of efficient labels make immunoassay one of the most popular analytical techniques today. Enzyme-linked immunosorbent assay (ELISA) is most widely used, since the enzyme label can be used as a catalyst t

The subject of this thesis is complement inhibitor C4b-binding protein (C4BP), on which we have performed both structural and functional studies. Complement is part of the innate immune defence and eliminates microbes, solubilises immune complexes and is involved in the clearance of apoptotic cells. The actions of the complement system must be carefully controlled by proteins such as C4BP to avoid

Deterioration of concrete structures is a worldwide problem. Environmental exposure is known to affect concrete strength in structures. While moisture affects rebound values by lowering them, carbonation does the opposite. The aim of the study was to determine the in-situ concrete strength of three bridge elements, namely, pier, abutment and deck and evaluate the environmental conditions such as m

In this thesis, I have focused on five main research areas: 1). A new type of imprinted polymer has been developed, namely the amide MIP. The amide functional monomers showed better hydrogen bonding capabilities in polar organic solvents and the resulting polymers exhibited good enantiomeric recognition properties in organic media. Furthermore, by using the amide monomers instead of the carboxyl m

Medborgardialoger blir en allt vanligare metod för att stärka den representativa demokratin och uppmuntra till aktivt politiskt deltagande. Trots den allt större spridningen av metoden har den kritiserats för att potentiellt kunna öka den politiska ojämlikhet som finns mellan grupper i samhället. Sveriges Kommuner och Landsting har i syfte att utveckla och förbättra arbetet med medborgardialoger t

The construction of Passive Houses is challenging. On one hand, there is a strong pressure to reduce the investment cost and on the other hand optimal energy efficiency should be reached. Hence that it is indispensable for architects, engineers, and constructors to avoid any causes throughout the whole project, that would lead to performance gaps and costs overruns. The purpose of this degree proj

Vehicle to everything (V2x) communication is one of the most researched topics today. The main goal behind this new emerging technology is road safety along with traffic and energy efficiency. Vehicular communications can further be sub-divided into certain types. One such type is vehicle to vehicle (V2V) communication, which is the focus of this thesis. V2V is either Wireless Local Area Network (

I praktiken sker försäljningar av kommersiella fastigheter i stor utsträckning genom aktieförsäljning. Fastigheten paketeras och säljs som ett aktiebolag och utgör i typfallet den enda tillgången i bolaget. De omedelbara beskattningseffekterna som följer av fastighetspaketering är avsevärt mindre än vad en motsvarande fastighetsförsäljning medför. Under 2015 var cirka 90% av värdet av omsättningenCommercial real estate is in practice oftentimes not sold by direct sales, but instead by sales of shares of a limited company. The property is packaged and sold as a limited company and, in a typical case, constitutes the only asset in the company. The immediate tax consequences followed by packaging of real estate are substantially less than what a corresponding real estate sale entails. During