Filtyp
The molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. The studies in th
Popular Abstract in Swedish INTRODUKTION Aminosyror är en grupp små molekyler som finns i våra celler. Totalt finns det tjugo olika aminosyror, vilka kan binda till varandra i långa kedjor varvid de bildar proteiner (äggviteämnen). Proteiner ansvarar för en lång rad funktioner i organismen och varje cell i en organism måste därför kunna syntetisera ett par tusen olika proteiner för att kroppen ska1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indica
Popular Abstract in Swedish Det mesta av det genetiska materialet i en eukaryot cell finns samlat till kärnan och är organiserat i kromosomer. Varje gång en cell delas kopieras kromosomerna så att de båda resulterande cellerna får ett bibehållet kromosomantal. Den mekanism som styr denna replikeringsprocess förmår dock inte kopiera de yttersta kromosomändarna, vilket resulterar i att dessa blir koTelomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most eukaryotes is composed of tandemly arranged short repeats. Within the budding yeasts these repeats are diverged in length as well as in nucleotide composition. However, they contain a sequence resembling the consensus binding sequence of the major t
In the aftermath of the nuclear weapons testing and as compared with agriculture, the forest industry has received relatively little attention in spite of its large-scale use of radiocesium- contaminated wood and water. After the Chernobyl nuclear power plant accident in 1986, numerous studies of the forest environment have been conducted with respect to radionuclide transfer through the forest ec
Popular Abstract in Swedish Utgångspunkten för den här avhandlingen har varit det stora antalet bilder som motsäger den vanliga trenden i konst att avbilda flickor som oskyldiga, romantiska och sexualiserade. Målet med avhandlingen är att för första gången presentera forskning om den svenska konstnären Lena Cronqvists (född 1938) flickbilder och att skapa kunskap om bilder av flickor i konst i allThe starting point for this PhD, is the large number of girls that opposed the common trend in which girls are represented as innocent, romantic and sexual. The aim of this study has been to provide the first piece of research ever on this body of work by the Swedish artist Lena Cronqvist (b. 1938) and to cast new light on representations of girls in art in general. Cronqvist is one of Sweden's ma
Popular Abstract in Swedish Många växtarter kan inte kolonisera kalkjordar och det är stora skillnader i artsammansättningen mellan kalkjordar och närliggande surare jordar. Detta beteende kallas ofta för kalkskyende och tycks orsakas av en oförmåga hos dessa växtarter att lösa och ta upp fosfat och järn ur kalkjordar. Kalkjordar innehåller mycket låga halter av järn och fosfat löst i marklösninge
The aim of the present study was to analyse quantitatively, on a cat gastrocnemius preparation in vivo, the effects of i.a. or i.v. administered glyceryl trinitrate (GTN), sodium nitroprusside (SNP) or nitric oxide (NO dissolved in saline) on vascular resistance (tone) in the following consecutive vascular sections: Large-bore arterial resistance vessels (> 25 microns), small arterioles (< 25 micr
Popular Abstract in Swedish Protein kinas C (PKC) är en familj serin/treonin kinaser som har en viktig roll i regleringen av olika funktioner i cellen. PKC kan delas in i klassiska (alpha, betaI, betaII and gamma), nya (delta, epsilon, eta and theta) och atypiska (zeta and iota/lambda) isoformer beroende på skillnader i hur de regleras. När PKCalpha är inaktivt bidrar intramolekylära bindningar tiMembers of the protein kinase C (PKC) family of serine/threonine kinases play critical roles in cellular regulation. Depending on differences in regulation, PKCs can be divided into classical (alpha, betaI, betaII and gamma), novel (delta, epsilon, eta and theta) and atypical (zeta and iota/lambda) isoforms. When PKCalpha is inactive it is maintained in a closed conformation by intramolecular inte
Popular Abstract in Swedish Våtmarker är en naturtyp som man finner i övergångszoner mellan land och vatten. Idag talas det mycket om våtmarkers positiva natur- och miljövärden i avrinningsområden i det moderna jordbrukslandskapet. Våtmarker ger omväxling i landskapet och är viktiga biotoper för växter och djur. I våtmarker ansamlas mycket dött växtmaterial och tillsammans med en god tillgång på vIn this thesis, I have studied nitrogen turnover processes in watermeadows. A watermeadow is a wetland where water infiltrates through the soil of a grassland field. It is hypothesized that infiltration of water through the soil matrix promotes nutrient transformations compared to surface flow of water, by increasing the contact between water, nutrients, soil organic matter and bacteria. I have st
The pine sawfly, Diprion jingyuanensis Xiao et Zhang, is a serious pest of Chinese pine (Pinus tabulaeformis Carr.) in the northern parts of China. The general biology of this recently described sawfly species is little known and in the present study we used a synthetic pheromone to monitor its flight period and to evaluate the possibility to use pheromone traps as a tool for estimating and predic
We have previously identified C1 domain-containing phosphatase and TENsin homologue (C1-TEN) as being an intracellular binding partner for Axl receptor tyrosine kinase (RTK). C1-TEN is a tensin-related protein that houses an N-terminal region with predicted structural similarity to PTEN. Here, we report our observations on the effects of ectopic expression of C1-TEN in HEK293 cells, which resulted
Popular Abstract in Swedish Missbrukande kvinnor och mammor har ofta fördömts av samhället och av människor i sin omgivning. De har setts som ansvarslösa kvinnor och olämpliga mammor utifrån en samhällssyn, att barn och missbruk inte går ihop. De livshistoriska intervjuerna med missbrukande kvinnor och mammor, som avhandlingen bygger på visar, att kvinnorna både vill vara respektabla och ta väl haThe aim of the dissertation is to describe the conditions under which substance abusing women live with regard to their families, the substance abuse and treatment. The interaction between the substance abusing women and the institutional expectations is analysed from gender and class perspective. The dissertation is based on interviews with two groups of substance abusing women: 12 mothers, livin
To investigate why human immunodeficiency virus type 2 (HIV-2) is less virulent than HIV-1, the evolution of coreceptor usage, autologous neutralization, envelope sequence and glycosylation was studied in sequentially obtained virus isolates and sera from four HIV-2-infected individuals. Neutralization of primary HIV-2 isolates was tested by a cell line-based assay and IgG purified from patients'
Objectives: To investigate determinants of joint destruction and reduced bone mineral density (BMD) in postmenopausal women with active rheumatoid arthritis (RA) not treated with bisphosphonates or hormone replacement therapy and to evaluate if there are common markers of erosive disease and bone loss. Methods: BMD was measured using dual x ray absorptiometry and joint damage was examined by x ra
Study Design. Biomechanical analysis of the movement of the lumbar spinal nerve roots (NRs). Objectives. The characteristics of the movement of lumbar spinal NRs corresponding to the change of posture were three-dimensionally analyzed in nonsimulated and simulated adhesion conditions using a porcine model. Summary of Background Data. There is a paucity of data on the movement of NRs. Materials and
Colonies of N-2-fixing cyanobacteria are key players in supplying new nitrogen to the ocean, but the biological fate of this fixed nitrogen remains poorly constrained. Here, we report on aerobic and anaerobic microbial nitrogen transformation processes that co-occur within millimetre-sized cyanobacterial aggregates (Nodularia spumigena) collected in aerated surface waters in the Baltic Sea. Microe
