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Understanding the drivers of diversity and change in regional Neolithization trajectories has emerged as a major theme in World Prehistory with new insights appearing in many parts of the globe. In Northeast Asia, research on Neolithic transition over the past two decades has focused primarily on millet and rice domestication and their role in the rise of farming, social complexity, and early Chin
Popular Abstract in SwedishHögre utbildning står inför en rad stora utmaningar under det tjugoförsta århundradet. Personligt, flexibelt och öppet lärande utifrån ett livslångt lärande perspektiv är av största vikt. E-lärandet ses som en av de drivande krafterna för denna utveckling där kvalitet är av avgörande betydelse.Denna kvalitativa studie, fokuserar på benchmarking e-lärande i högre utbildniHigher education is facing a range of major challenges during the twenty-first century. Personalised, flexible and open learning are considered among the driving forces, thus, issues of quality must be urgently addressed.This qualitative, multiple-case-study research with single and cross-case analysis focuses on benchmarking e-learning in higher education. The results of this study include provid
A normal mineral metabolism is integral for skeletal development and preservation of bone integrity. Fibroblast growth factor 23 (FGF-23) is a bone-derived circulating factor that decreases serum concentrations of inorganic phosphorous (P-i) and 1,25-dihydroxyvitamin D-3 [1,25(OH)(2)D-3]. Increased FGF-23 expression is a direct or indirect culprit in several skeletal disorders; however, the relati
In birds the major histocompatibility complex (MHC) organization differs both among and within orders; chickens Gallus gallus of the order Galliformes have a simple arrangement, while many songbirds of the order Passeriformes have a more complex arrangement with larger numbers of MHC class I and II genes. Chicken MHC genes are found at two independent loci, classical MHC-B and non-classical MHC-Y,
Objective: To examine the relationship of knee malalignment with occurrence of incident and enlarging bone marrow lesions (BMLs) and regression of BMLs. Methods: Subjects from the Multicenter Osteoarthritis Study aged 50-79 years with or at high risk of knee osteoarthritis were studied. Full-limb radiographs were taken at baseline and hip-knee-ankle mechanical axis was measured. Baseline and 30-mo
Background Plasma triglyceride levels are heritable and are correlated with the risk of coronary heart disease. Sequencing of the protein-coding regions of the human genome (the exome) has the potential to identify rare mutations that have a large effect on phenotype. Methods We sequenced the protein-coding regions of 18,666 genes in each of 3734 participants of European or African ancestry in the
Popular Abstract in Swedish I Immi Lundins avhandling Att föra det egna till torgs står 1960-, 1970- och 1980-talen i fokus. Tre kvinnliga författares debutromaner, en från varje decennium, undersöks och sätts i relation till de förändrade positionerna i den offentliga kvinno- och litteraturdebatten under trettioårsperioden. Frågan som avhandlingen söker svar på gäller romanernas samspel med tillkThe Swedish debate both on the role of literature and on the social position of women underwent rapid change during the thirty years from 1960 to 1990. In Bringing the Personal to Market: Narrative, Subject-Matter and Contemporary History in the First Novels of Kerstin Strandberg, Enel Melberg and Eva Adolfsson, the debut novels of three female authors’ are close-read from a thematic and narratolo
Background: Total hip joint replacement (THR) is a high volume, effective intervention for hip osteoarthritis (OA). However, indications and determinants of outcome remain unclear. The 'EUROHIP consortium' has undertaken a cohort study to investigate these questions. This paper describes the variations in disease severity in this cohort and the relationships between clinical and radiographic sever
The palynofloral changes around the Cretaceous-Paleogene (K-Pg) mass extinction event reveal the fine details of vegetation response to a global environmental crisis-in this case an asteroid impact in Mexico 65.5 million years ago. Due to the extinction of several plant taxa at the K-Pg boundary, palynostratigraphy is a prime tool for localizing the Cretaceous-Paleogene boundary in non-marine succ
Fracture Liaison Services are the best model to prevent secondary fractures. The International Osteoporosis Foundation developed a Best Practice Framework to provide a quality benchmark. After a year of implementation, we confirmed that a single framework with set criteria is able to benchmark services across healthcare systems worldwide. Introduction Despite evidence for the clinical effectivenes
Popular Abstract in Swedish Under 1900-talet har stora förändringar skett i synen på buddhistisk meditation. Från att ha varit en övning som bara ägt rum på kloster och bland ett fåtal munkar, har både ordinerade lärare och lekmannalärare börjat lära ut meditation till lekfolk. Meditation har kommit att framställas som själva hjärtat i buddhistiska traditioner, och som det element som kan isolerasThe purpose of this study is to investigate how a religious tradition changes when transposed to a new context: how it is received and incorporated in its new context and how individuals in Sweden perceive and make use of this tradition. This is done by highlighting the development of insight meditation, Vipassana, and more specifically, the Burmese practice lineage originating from the Burmese la
This thesis has evaluated the immunological- and epidemiological aspects of human papillomavirus transmission dynamics and its effect on circumcision. Effective prophylactic vaccines are based on type-specific neutralizing antibodies. A major neutralizing epitope is defined by the monoclonal antibody H16.V5. To investigate the importance of this epitope for overall immunogenicity of HPV16, we en
Abstract in UndeterminedUzbekistan, after gaining independence from the Soviet Union in 1991, had publicly declared that it would adhere to democratic governance principles in designing and implementing its public administration policies. As a newly-independent state with democracy claims, Uzbekistan had tried to establish new democratic institutions with an effort to capture international communi
Estimates of relevant source area of pollen (RSAP) and relative pollen productivity (PPE) are critical parameters for quantitative reconstructions of past vegetation and land cover. This study provides estimates for PPE relative to Poaceae for ten taxa, characterizing the cultural landscape of south Estonia and the RSAP for 40 lakes with an average radius of approximately 100 m (22-274 m, average
This thesis aimed to search for epidemiological evidence supporting the associations of type 2 diabetes mellitus (T2DM) with cancer and autoimmune diseases (ADs) by analysing several Swedish national registries. T2DM shares risk factors with cancer, such as obesity, diet, stress, and physical inactivity. However, it is unclear whether the associations with several types of cancers are due to share
1. A new methodological approach for detailed study of the organization of the cerebellar corticonuclear projection was evaluated in barbiturate-anaesthetized cats. Extracellular field potentials were simultaneously recorded in nucleus interpositus anterior and in the forelimb area of the C3 zone, at the cerebellar surface. On electrical and natural stimulation of the forelimb skin, the evoked pos
Background: The Btk (Bruton's tyrosine kinase) gene has been shown to be mutated in the human immunodeficiency disease, XLA (X-linked agammaglobulinemia). Btk is a member of the Tec family of cytosolic protein tyrosine kinases with distinct functional domains PH, TH, SH3, SH2, and kinase. Mutations have been observed in each of the Btk subdomains in XLA. We have analyzed the Btk gene in six XLA pa
I Indien är skillnaderna mellan pojkar och flickor påtagliga. Pojkarna ska försörja familjen när de blir vuxna, medan flickor ska giftas bort, ibland långt innan de har blivit vuxna. Detta märks tydligt på skillnaden i kvantitet skolgång som de får. Pojkars skolgång prioriteras framför flickors och för bara några år sedan skilde det över 20 procentenheter mellan läs- och skrivkunniga kvinnor och m
