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Generation of molecular recognition sites in electrospun polymer nanofibers via molecular imprinting

A DFT investigation on structural and redox properties of a synthetic Fe6S6 assembly closely related to the [FeFe]-hydrogenases active site

Association of the Collagen Type 1 (COL1A 1) Sp1 Binding Site Polymorphism to Femoral Neck Bone Mineral Density and Wrist Fracture in 1044 Elderly Swedish Women.

Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling

Protein C (PC) is activated to an essential anticoagulant enzyme (activated PC or APC) by thrombin (T) bound to thrombomodulin (TM), a membrane receptor present on the surface of endothelial cells. The understanding of this complex biological system is in part limited due to the lack of integration of experimental and structural data. In the work presented here, we analyze the PC-T-TM pathway in t

Synthesis, Structures and Oxo Transfer Reactivity of bis(Dithiolene) Tungsten(IV,VI) Complexes Related to the Active Sites of Tungstoenzymes

Comparison of PM_2.5 chemical composition and sources at a rural background site in Central Europe between 1993/1994/1995 and 2009/2010 : Effect of legislative regulations and economic transformation on the air quality

A New Process-Based Soil Methane Scheme : Evaluation Over Arctic Field Sites With the ISBA Land Surface Model

Permafrost soils and arctic wetlands methane emissions represent an important challenge for modeling the future climate. Here we present a process-based model designed to correctly represent the main thermal, hydrological, and biogeochemical processes related to these emissions for general land surface modeling. We propose a new multilayer soil carbon and gas module within the Interaction Soil-Bio

Hippocampus and basal ganglia as potential sentinel sites for ischemic pathology after resuscitated cardiac arrest

Aims of the study: Neurological impairment after resuscitated cardiac arrest (CA) remains a significant unmet medical need. Brain ischemia associated with CA and subsequent reperfusion is evident as two fundamentally different types of damage on neuropathological examination: frank necrosis (involving all cell types) and selective eosinophilic neuronal death (SEND). These types of damage are not o

Process design and economics of on-site cellulase production on various carbon sources in a softwood-based ethanol plant.

A preliminary study of telemedicine for patients with hepatic glycogen storage disease and their healthcare providers : from bedside to home site monitoring

Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNP A1) and hnRNP A2 Inhibit Splicing to Human Papillomavirus 16 Splice Site SA409 through a UAG-Containing Sequence in the E7 Coding Region

Protocol for a multi-site study of the effects of overdose prevention education with naloxone distribution program in Skåne County, Sweden

Background: Continuously high rates of overdose deaths in Sweden led to the decision by the Skåne County to initiate the first regional take-home naloxone program in Sweden. The project aims to study the effect of overdose prevention education and naloxone distribution on overdose mortality in Skåne County. Secondary outcome measures include non-fatal overdoses and overdose-related harm in the gen

A novel function for CDK2 activity at meiotic crossover sites

Severe retinal degeneration at an early age in Usher syndrome type 1B associated with homozygous splice site mutations in MYO7A gene

Consensual Approaches to Siting Controversy

Small-Scale Reforming for On-Site Hydrogen Supply

New insights into PKC family affairs: three novel phosphorylation sites in PKCepsilon and at least one is regulated by PKCalpha.

PKCepsilon (protein kinase Cepsilon) is a serine/threonine kinase, and a member of the PKC family of isoforms. The different PKC isoforms regulate many cellular processes of importance for disease. It is therefore desirable to obtain tools to specifically modulate the activity of the individual isoforms and to develop markers of PKC activity. The paper by Durgan et al. in this issue of the Biochem

In situ observations of the isotopic composition of methane at the Cabauw tall tower site

High-precision analyses of the isotopic composition of methane in ambient air can potentially be used to discriminate between different source categories. Due to the complexity of isotope ratio measurements, such analyses have generally been performed in the laboratory on air samples collected in the field. This poses a limitation on the temporal resolution at which the isotopic composition can be

Species and emm-type distribution of group C and G streptococci from different sites of isolation

Upper Pleistocene palaeoenvironmental changes at the Zwierzyniec site, Central Poland