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1. In the rat hepatic artery, the acetylcholine-induced relaxation mediated by endothelium-derived hyperpolarizing factor (EDHF) is abolished by a combination of apamin and charybdotoxin, inhibitors of small (SK(Ca)) and large (BK(Ca)) conductance calcium-sensitive potassium (K)-channels, respectively, but not by each toxin alone. The selective BK(Ca) inhibitor iberiotoxin cannot replace charybdot

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AbstractCardiac resynchronization therapy (CRT) has improved quality of life and survival in select heart faillure patients, however 30-40% of patients do not show objective benefit from the treatment. At the same time there is little evidence about the long term effect of changes in medical treatment in these patients. Several factors have been examined to improve the response rate in the ”non-re

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A growing body of consumer culture theory (CCT) research has pointed to the way that places are increasingly conceptualised and commodified as brands and consumption objects (Lichrou et al., 2008; Giovanardi et al., 2018). Research has explored consumers’ experiences with different kinds of spaces and places, including retail settings (e.g. Penaloza, 1998; Kozinets et al., 2004; Maclaran & Bro

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Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leading to a hemolytic transfusion reaction. Antigenic differences can also cause hemolytic disease of thefetus and newborn (HDFN). Blood group antigens are implicate

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The rise in CDOM (coloured dissloved organic matter) is likely to be relatively more pronounced in remote northern regions. However, there is a lack of monitoring to confirm this. For this reason, there is a strong incentive to develop remote sensing-based methods to map CDOM in lakes across broader geographical scales and to include geograghic contex in such analysis. There is a lack of understan

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This research is a case study of the social activism experiences of Ai Xiaoming, a literature professor, feminist, rights activist, and independent documentary filmmaker. The research addresses the broad struggle for recognition and representation of feminists, activists, independent filmmakers, public intellectuals and scholars in digital China. The analysis of her case has led to the creation of

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Windmill structures must withstand very high horizontal loading giving an extremely large overturning moment on the foundation. These structures have very low stability loads in comparison to the overturning loads. The traditional way to solve the construction problem uses a shallow foundation with a massive concrete volume or a piled foundation to resist the extreme overturning moment. This work

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This dissertation examines the public interventions, rhetoric, and actions of liberal intellectuals in Turkey between the early 1990sand 2012 regarding the rights of Kurdish and Islamic actors and restrictions on discussing the Armenian Genocide of 1915. Theanalysis of diverse texts published by the interconnected intellectuals – newspaper columns, academic articles, policy papers,reports, and man

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Popular Abstract in Swedish Oberoende av vilket bränsle som används ger förbränning upphov till utsläpp av miljöfarliga gaser, såsom kväveoxider, svaveldioxider, kolmonoxid och oförbrända kolväten. Dessa ämnen bidrar till försurning, smog, växthuseffekten och kan skada ozonlagret. Även koldioxid kan anses som en miljöfarlig gas då den bidrar till den globala uppvärmningen. För att få en bättre förIn the work presented in this thesis, different laser-based techniques were employed for measurements in different combustion devices. Laser-based techniques enable non-intrusive and in-situ measurements to be carried out, in which high spatial and temporal resolution can be obtained. Different parameters related to combustion research can be visualized, such as species concentrations, temperature

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Eastern New South Wales (NSW), Australia, is a region prone to frequent and intense droughts. An unprecedented episode of high temperatures and low rainfall in 2017–2019 culminating in the 2019-2020 summer triggered massive canopy dieback of eucalypt forests throughout the region. Subsequent high rainfall in 2020 offered a unique and rare opportunity to study the process of vegetation recovery fol

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The immune system is of central importance to clear-off pathogens in order to keep an organism healthy. In vertebrates, the Major Histocompatibility Complex (MHC) is a genomic region that holds key genes involved in adaptive immunity and in particular in the antigen presenting process. The presentation relies on MHC class I (MHC-I) and MHC class II (MHC-II) molecules that are encoded by MHC-I and

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Objective: Our report describes clinical, genetic, and biochemical features of participants with a molecularly confirmed congenital disorder of glycosylation (CDG) enrolled in the Frontiers in Congenital Disorders of Glycosylation (FCDGC) Natural History cohort at year 5 of the study. Methods: We enrolled individuals with a known or suspected CDG into the FCDGC Natural History Study, a multicenter

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Uncertainty in our calculations of a system reveals the limits of our knowledge. This limitation makes model representations of the Earth system challenging and our predictions less reliable. However, despite appearing chaotic and non-linear, a system always follows a deterministic trajectory, which can often be expressed probabilistically. Building on this concept, this thesis applies data assimi

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Viking Age silver is a useful tool for tracing various aspects of the society. Contact networks, trade organization, society structure, economic variation etc. This paper concentrates on the so-called Permian rings, which appear in Scandinavian silver hoards from Early Viking Age. Their main concentration is, however, in the regions west of the Ural Mountains in Russia. As the rings found in Russi

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Hydrofluorocarbons (HFCs) are used in a range of industrial applications and have largely replaced previously used gases (CFCs and HCFCs). HFCs are not ozone-depleting but have large global warming potentials and are, therefore, reported to the United Nations Framework Convention on Climate Change (UNFCCC). Here, we use four independent inverse models to estimate European emissions of the two HFCs

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Beginning What and Ending Away is Rosa Barba’s first solo exhibition in Korea. On view is a film installation, three kinetic sculptures using celluloid, a wax sculpture and works from her series entitled Weavers, panels of woven film.Rosa Barba’s practice merges films, sculptures, installations, live-performances, text pieces, and publications that are grounded in the material and conceptual quali

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Introduction Parkinson’s disease (PD) is a common neurodegenerative disease, which has extensive pathology that critically includes the loss of midbrain dopaminergic neurons. This loss leads to debilitating motor features such as bradykinesia and rigidity, as well as some non-motor symptoms. Intracerebral dopamine cell transplants have been explored for many years as a new approach to treating PD

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Background: Adverse events induced by intravesical bacillus Calmette-Guérin (BCG) to treat high-grade non–muscle-invasive bladder cancer (NMIBC) often lead to treatment discontinuation. The EAU-RF NIMBUS trial found a reduced number of standard-dose BCG instillations to be inferior with the standard regimen. Nonetheless, it remains important to evaluate whether patients in the reduced BCG treatmen

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The breakup of the L-chondrite parent body (LCPB) in the asteroid belt at 466 Ma ago is the largest asteroid breakup documented in Earth's geological record for the past ca. three billion years. Recovery of abundant macroscopic fossil L chondrites in mid-Ordovician marine sediments as well as reconstructions of the flux of micrometeoritic chrome spinel through the ages have given much new informat