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The Epithelial Science Expert Group convened on 18–19 October 2023, in Naples, Italy, to discuss the current understanding of the fundamental role of the airway epithelium in asthma and other respiratory diseases and to explore the future direction of patient care. This review summarises the key concepts and research questions that were raised. As an introduction to the epithelial era of research,
Recently, work conducted by the European Commission’s Joint Research Centre demonstrated that Ireland had the highest prevalence of loneliness of all European countries. Given the range of adverse physical and psychological consequences associated with loneliness, it is vital to ask why Ireland is experiencing such high prevalence. Here, we discuss potential contributing factors, including: Irelan
The magnetic Laplacian on a planar domain under a strong constant magnetic field has eigenvalues close to the Landau levels. We study the case when the domain is a disc and the spectrum consists of branches of eigenvalues of one dimensional operators. Under Neumann boundary condition and strong magnetic field, we derive asymptotics of the eigenvalues with accurate estimates of exponentially small
One of the main challenges as the market for fully commercial electrified vehicles quickly expands is predicting the electromagnetic interference (EMI) in traction voltage systems (TVSs) in differential mode (DM) and common mode (CM). The number of subsystems connected to vehicle TVSs is increasing, and thus, so are the electromagnetic compatibility (EMC) requirements. These requirements should ma
When flying through narrow spaces, insects control their position by balancing the magnitude of apparent image motion (optic flow) experienced in each eye and their speed by holding this value about a desired set-point. Previously, it has been shown that when bumblebees encounter sudden changes in the proximity to nearby surfaces - as indicated by a change in the magnitude of optic flow on each si
The issue of pharmaceutical pollution has recently gained attention on the international political agenda as several actors have raised concern for its negative impact on ecosystems, human health, and livelihoods in emerging economies where an increasing share of the pharmaceutical production is located due to the cheaper labor and less stringent environmental regulations. In 2019, the OECD publis
In recent years, land acquisition has escalated due to increased global demand for food and fuel driven by population growth, urbanisation, and growing energy demand. Mozambique is ranked as one of the world’s top 10 countries with available land for agriculture, forestry and livestock production. Low labour costs and land taxes may further increase the interest in Mozambican land. In particular,
The fluctuations of the price in the energy market affect the households, firms and the government intuitions. We can perceive the information of the energy market from daily economic news. The entire society is concerned for the events that affect the energy market and the changing prices of the energy resources. It is thus meaningful and interesting to study the risk of the energy market. This p
The purpose of this thesis is to determine how electric vehicle trucks can meet the needs of customers in the urban building and construction sector. This sector contributes significantly to greenhouse gas (GHG) emissions, and also creates noise and other disturbances in urban environments. There are multiple benefits that come with electric trucks, which can address these issues if they are used
Due to the focus of their study program, environmental and sustainability students are vulnerable to experience negative emotional impacts, potentially affecting their mental health. This thesis contributes to increased understanding of emotions and emotional resilience in relation to the climate crisis by examining experienced emotions, studying the power students have over their emotions, and po
As the need to adapt to a changing climate and the political rhetoric in this regard are growing, Berlin’s Senate has issued strategic policies – complemented by an increase of funding. Berlin’s socio-cultural features and place-based factors seem predisposed for so-called “Nature-based Solutions” (NbS) that can support the achievement of adaptation efforts. This encouraging context seems to be co
Climate change is the greatest challenge of our time. Despite efforts to reduce greenhouse gas (GHG), the emissions contribution from global aviation is set to increase. Electric aviation has emerged as an alternative which could form part of the solution. Sweden, which is on the path to carbon neutrality and has a long history in aviation, could contribute to the global efforts in mitigating clim
The general Z2-violating two-Higgs-doublet model (2HDM) is analysed as an explanation for the discrepancy between Standard Model predictions and experimental measurements of the muon anomalous magnetic dipole moment ∆aµ, with the condition that it does not provide an electron electric dipole moment |eEDM| larger than experimental bounds. Several point studies of individual 2HDM parameter space poi
PtdIns-4,5-bisphosphate is a lipid messenger of eukaryotic cells playing critical roles in processes such as cytoskeleton organization, intracellular vesicular trafficking, secretion, cell motility, regulation of ion channels and nuclear signalling pathways. The enzymes responsible for the synthesis of PtdIns(4,5)P(2) are phosphatidylinositol phosphate kinases (PIPKs). The moss Physcomitrella pate
To improve population health, it is important to create environments that support activity, participation and health. One crucial aspect concerns the degree to which the built environment is accessible for all people including those with reduced functional capacity. The overarching objective of this thesis was to explore and further develop methodology for accessibility assessments based on the no
Disasters such as the storms that affected Sweden in 2005 and 2007 showed that citizens initially conducted a large part of the disaster response, such as clearing roads, giving psychosocial support to affected neighbours and repairing power lines in collaboration with power companies. As a result of these storms, an Emergent Citizen Group (ECG) was established in a village which continued to work
Background: Gaucher disease (GD) is the most common inherited lysosomal storage disorder in humans, caused by mutations in the gene encoding the lysosomal enzyme glucocerebrosidase (GBA1). GD is clinically heterogeneous and although the type of GBA1 mutation plays a role in determining the type of GD, it does not explain the clinical variability seen among patients. Cumulative evidence from recent
As the title largely illustrates, this study seeks to investigate, from a diplomatic-history and geostrategic perspective, the key developments in Anglo-Iranian relations during what may best be dubbed their “formative years,” ranging from 1907 to 1953. Having thus provided a glimpse into pre-twentieth-century Persian–British relations, it moves to analyze the division of Persia into two spheres o
This study evaluates whether the use of an acceleration advisor leads to fuel savings, to determine the change in traffic-related emissions and to analyse changes in driving patterns on various routes. The acceleration advisor provides advice to drivers through resistance in the accelerator pedal when they try to accelerate rapidly. In a test carried out in Southern Sweden, the acceleration adviso
