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This chapter is centered on the importance of letting learners take the lead in their lifelong educational journey, meeting the challenges that they encounter. Additionally, the chapter focuses on new modes of learning in the digital era. The role transfers and professional development of managers, leaders, and academics are discussed, as well as the need for the development of digital academic sc

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Sepsis is a systemic immune response responsible for considerable morbidity and mortality. Molecular modeling of host-pathogen interactions in the disease state represents a promising strategy to define molecular events of importance for the transition from superficial to invasive infectious diseases. Here we used the Gram-positive bacterium Streptococcus pyogenes as a model system to establish a

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Aim: The prevalence and severity of urinary incontinence (UI) increase with age and comorbidity. The benefits of pharmacotherapy for UI in the elderly are questionable. The aim of the present study was to systematically review the efficacy of pharmacological treatment for UI in the elderly and frail elderly. Methods: We searched PubMed, EMBASE, Cochrane library and Cinahl databases through October

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Our aim was to identify a cut-off value for self-reported, abnormal cold sensitivity and to identify cold sensitivity predictors after hand injuries. The Cold Intolerance Symptom Severity (CISS) questionnaire and a VAS question concerning discomfort on exposure to cold were investigated in 94 normal people and 88 patients. A CISS score >450 was defined as abnormal cold sensitivity. Multiple injure

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A total of 308,036 women were selected from the European Prospective Investigation into Cancer and Nutrition (EPIC) study to evaluate the association between tobacco smoking and the risk of cervical intraepithelial neoplasia of grade 3 (CIN3)/carcinoma in situ (CIS) and invasive cervical cancer (ICC). At baseline, participants completed a questionnaire and provided blood samples. During a mean fol

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The role of inflammation in atherosclerosis and plaque vulnerability is well recognized. However, it is only during recent years it has become evident that this inflammation is modulated by immune responses against plaque antigens such as oxidized LDL. Interestingly, both protective and pathogenic immune responses exist and experimental data from animal studies suggest that modulation of these imm

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The best valve substitute for aortic valve replacement (AVR) in terms of hemodynamic performance, durability, incidence of complications, and survival remains the subject of much debate. It has been suggested that valve performance is influenced by the potentially modifiable variable prosthesis-patient mismatch (PPM). PPM has been reported to be detrimental for survival and symptom resolution main

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The complex structural behavior of tau-[AgCu](similar to 0.92)V4O10 has been elucidated by single crystal X-ray diffraction and thermal analysis. The tau-phase region is apparently composed of several distinct phases and this study identifies at least three: tau(1rt) tau(2rt) and tau(1t), tau(1rt) and tau(2rt) have slightly different compositions and crystal habits. Both phases transform to Tit at

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Chromosomal translocations of transcription factors generating fusion proteins with aberrant transcriptional activity are common in acute leukemia. In acute promyelocytic leukemia (APL), the promyelocytic leukemia-retinoic-acid receptor alpha (PML-RARA) fusion protein, which emerges as a consequence of the t(15;17) translocation, acts as a transcriptional repressor that blocks neutrophil different

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We have recently reported Monte Carlo simulations for a system of two infinite like-charged plates in a dipolar fluid solvent (Pegado et al 2008 J. Chem. Phys. at press). The pressure as a function of plate separation qualitatively reproduces the ion-ion correlation attraction picture seen in primitive model studies, where the solvent only enters the picture implicitly through its dielectric const

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Due to the involvement of calpains and calpastatin in the pathology of several diseases, it is important to create an analytical tool for their accurate and sensitive measurements. In this work, an amperometric immunoassay (AIA) was developed and optimized for quantification of two key proteins from the calpain proteolytic system. The detection is based on the measurement of a steady-state current

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I denna avhandling har jag kritiserat EPI (Environmental Performance Index) och det sätt ett lands hållbarhetspolicy tenderar att mätas. Jag har granskat tidigare bortsedda aspekter av nationernas miljöpolicy och försökt föra dem fram i hopp om att dessa kommer att användas för framtida miljömätningar. Jag har också tittat på sambandet mellan jämställdhet och statlig miljö och försökt hitta empiri

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This thesis explores the European Commission’s proposal on General Reverse Charge Mechanism. VAT is a final tax on consumption. It is imposed on every transaction in the supply chain with the general aim of being deductible and thus being neutral for businesses with the right to deduct. The initial aim of the VAT system was to operate as if all the transactions occurred in one single country; howe

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The purpose of this study is to explore the opportunities and challenges for self-employed artists who use social media for their business. The research is focused on painters and illustrators who have digitalised and commercialised their own artwork. The method follows a qualitative research framework with a comparative design of multiple cases on the level of individual artists. Seven artists fr

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Purpose: The purpose of this study was two-fold. First, we aimed to develop a framework concerning how to directly and indirectly control discrimination in the workplace using Man- agement Control Systems (MCS). Second, we wanted to examine whether this framework is practically applicable in multinational enterprises (MNE). Methodology: The first part of the purpose was achieved through conduc

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Urbanisation is an inevitable part of globalisation. With the globalised food chain in place to feed the growing number of people living in urban areas. A remedy is often expressed to be urban farming, with local, sustainable production of food. This study presents a preliminary assessment of the dynamics between urban farms and residents in Malmö. Urban farms produce available food for the reside

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The Swedish construction industry is subject to a high rate of occupational injuries, where overload factors are a significant cause. Through Human Activity Recognition, movement data can be collected and analyzed, enabling the identification of harmful movement patterns with the use of machine learning. This study aims to describe the environmental barriers and stakeholder attitudes towards a sma

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This is a qualitative study on the characters of Ronja, the robber’s daughter and how they have been interpreted in Studio Ghibli’s anime version. It focuses on characterization from the perspective of role language and character language and how they reinforce the themes and characters of Ronja. Example sentences have been analyzed and discussed from various major characters. In summary, role lan